标题
mTORC1 and the regulation of skeletal muscle anabolism and mass
作者
关键词
-
出版物
Applied Physiology Nutrition and Metabolism
Volume 37, Issue 3, Pages 395-406
出版商
Canadian Science Publishing
发表日期
2012-05-03
DOI
10.1139/h2012-009
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle
- (2014) Cristina Mammucari et al. Autophagy
- Skeletal muscle protein synthesis and the abundance of the mRNA translation initiation repressor PDCD4 are inversely regulated by fasting and refeeding in rats
- (2011) Sana Zargar et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- mTOR binds to the promoters of RNA polymerase I- and III-transcribed genes
- (2011) Chi Kwan Tsang et al. CELL CYCLE
- Amino Acid Signaling to mTOR Mediated by Inositol Polyphosphate Multikinase
- (2011) Seyun Kim et al. Cell Metabolism
- Two faces of drug therapy in cancer: drug-related lean tissue loss and its adverse consequences to survival and toxicity
- (2011) Carla MM Prado et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Rac1 Regulates the Activity of mTORC1 and mTORC2 and Controls Cellular Size
- (2011) Abdelhafid Saci et al. MOLECULAR CELL
- Unknown
- (2011) Abid Kazi et al. MOLECULAR MEDICINE
- Lysosomal positioning coordinates cellular nutrient responses
- (2011) Viktor I. Korolchuk et al. NATURE CELL BIOLOGY
- Transcriptional mechanisms regulating skeletal muscle differentiation, growth and homeostasis
- (2011) Thomas Braun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK
- (2011) L. Shang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling
- (2011) Y. Yu et al. SCIENCE
- The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling
- (2011) P. P. Hsu et al. SCIENCE
- Oxidative stress, apoptosis, and proteolysis in skeletal muscle repair after unloading
- (2010) Tina Andrianjafiniony et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine
- (2010) Charles H. Lang et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Low body mass index and sarcopenia associated with dose-limiting toxicity of sorafenib in patients with renal cell carcinoma
- (2010) S. Antoun et al. ANNALS OF ONCOLOGY
- Muscle Wasting in Cancer Cachexia: Clinical Implications, Diagnosis, and Emerging Treatment Strategies
- (2010) Shontelle Dodson et al. Annual Review of Medicine
- Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo
- (2010) Terry OʼReilly et al. ANTI-CANCER DRUGS
- Little change in markers of protein breakdown and oxidative stress in humans in immobilization-induced skeletal muscle atrophy
- (2010) Elisa I. Glover et al. Applied Physiology Nutrition and Metabolism
- Fasting-related autophagic response in slow- and fast-twitch skeletal muscle
- (2010) Tomonori Ogata et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- DAP1, a Novel Substrate of mTOR, Negatively Regulates Autophagy
- (2010) Itay Koren et al. CURRENT BIOLOGY
- mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide
- (2010) Won Jun Oh et al. EMBO JOURNAL
- Coordinated maintenance of muscle cell size control by AMP-activated protein kinase
- (2010) Louise Lantier et al. FASEB JOURNAL
- mTOR regulation of autophagy
- (2010) Chang Hwa Jung et al. FEBS LETTERS
- Effects of 3 days unloading on molecular regulators of muscle size in humans
- (2010) T. Gustafsson et al. JOURNAL OF APPLIED PHYSIOLOGY
- The abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age
- (2010) Agus Suryawan et al. JOURNAL OF APPLIED PHYSIOLOGY
- Requirement of the mTOR Kinase for the Regulation of Maf1 Phosphorylation and Control of RNA Polymerase III-dependent Transcription in Cancer Cells
- (2010) Boris Shor et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amino Acids Activate Mammalian Target of Rapamycin Complex 2 (mTORC2) via PI3K/Akt Signaling
- (2010) Irantzu Tato et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Control of Translation Initiation through Integration of Signals Generated by Hormones, Nutrients, and Exercise
- (2010) Scot R. Kimball et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)
- (2010) Audrey Carriere et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly
- (2010) Takeshi Kaizuka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis
- (2010) Yuting Sun et al. JOURNAL OF CELL BIOLOGY
- Association of Skeletal Muscle Wasting With Treatment With Sorafenib in Patients With Advanced Renal Cell Carcinoma: Results From a Placebo-Controlled Study
- (2010) Sami Antoun et al. JOURNAL OF CLINICAL ONCOLOGY
- Early Time Course of Akt Phosphorylation after Endurance and Resistance Exercise
- (2010) DONNY M. CAMERA et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Cyclic AMP Controls mTOR through Regulation of the Dynamic Interaction between Rheb and Phosphodiesterase 4D
- (2010) H. W. Kim et al. MOLECULAR AND CELLULAR BIOLOGY
- mTORC1 Directly Phosphorylates and Regulates Human MAF1
- (2010) A. A. Michels et al. MOLECULAR AND CELLULAR BIOLOGY
- A Phosphatidylinositol 3-Kinase/Protein Kinase B-independent Activation of Mammalian Target of Rapamycin Signaling Is Sufficient to Induce Skeletal Muscle Hypertrophy
- (2010) Craig A. Goodman et al. MOLECULAR BIOLOGY OF THE CELL
- PP2AT61ɛ Is an Inhibitor of MAP4K3 in Nutrient Signaling to mTOR
- (2010) Lijun Yan et al. MOLECULAR CELL
- Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
- (2010) Shomit Sengupta et al. MOLECULAR CELL
- Termination of autophagy and reformation of lysosomes regulated by mTOR
- (2010) Li Yu et al. NATURE
- Hypoxia converts the myogenic action of insulin-like growth factors into mitogenic action by differentially regulating multiple signaling pathways
- (2010) H. Ren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1
- (2010) T. Kantidakis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs
- (2010) R. J. O. Dowling et al. SCIENCE
- mTORC1 signaling: what we still don't know
- (2010) X. Wang et al. Journal of Molecular Cell Biology
- Intramyocellular Lipids: Effect of Age, Obesity, and Exercise
- (2010) Ruth M. Franklin et al. PHYSICIAN AND SPORTSMEDICINE
- Resistance exercise and nutrition to counteract muscle wasting
- (2009) Jonathan P. Little et al. Applied Physiology Nutrition and Metabolism
- Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)
- (2009) Juan M. García-Martínez et al. BIOCHEMICAL JOURNAL
- Dissecting the role of mTOR: Lessons from mTOR inhibitors
- (2009) Ryan J.O. Dowling et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity
- (2009) C. M. Chresta et al. CANCER RESEARCH
- Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin
- (2009) K. Yu et al. CANCER RESEARCH
- DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival
- (2009) Timothy R. Peterson et al. CELL
- A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
- (2009) Christopher B. Newgard et al. Cell Metabolism
- Sarcopenia as a Determinant of Chemotherapy Toxicity and Time to Tumor Progression in Metastatic Breast Cancer Patients Receiving Capecitabine Treatment
- (2009) C. M.M. Prado et al. CLINICAL CANCER RESEARCH
- An Emerging Role of mTOR in Lipid Biosynthesis
- (2009) Mathieu Laplante et al. CURRENT BIOLOGY
- Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation
- (2009) Jean-François Tanti et al. CURRENT OPINION IN PHARMACOLOGY
- Diabetes, Muscles, and the Myth of Ulysses' Bow
- (2009) L. Ferrucci et al. DIABETES CARE
- Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes
- (2009) R. A. DeFronzo et al. DIABETES CARE
- Important role for AMPKα1 in limiting skeletal muscle cell hypertrophy
- (2009) Rémi Mounier et al. FASEB JOURNAL
- Mechanisms of Muscle Atrophy Induced by Glucocorticoids
- (2009) O. Schakman et al. HORMONE RESEARCH
- Resistance exercise with whey protein ingestion affects mTOR signaling pathway and myostatin in men
- (2009) Juha J. Hulmi et al. JOURNAL OF APPLIED PHYSIOLOGY
- Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans
- (2009) David L. Mayhew et al. JOURNAL OF APPLIED PHYSIOLOGY
- Alterations of protein turnover underlying disuse atrophy in human skeletal muscle
- (2009) S. M. Phillips et al. JOURNAL OF APPLIED PHYSIOLOGY
- An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
- (2009) Carson C. Thoreen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy
- (2009) Valérie Risson et al. JOURNAL OF CELL BIOLOGY
- During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation
- (2009) Shenhav Cohen et al. JOURNAL OF CELL BIOLOGY
- mTOR signaling at a glance
- (2009) M. Laplante et al. JOURNAL OF CELL SCIENCE
- The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions
- (2009) T. K. O’Neil et al. JOURNAL OF PHYSIOLOGY-LONDON
- Human Muscle Gene Expression following Resistance Exercise and Blood Flow Restriction
- (2009) MICAH J. DRUMMOND et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1
- (2009) C. C. Dibble et al. MOLECULAR AND CELLULAR BIOLOGY
- Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats
- (2009) Nobuhide Agata et al. MUSCLE & NERVE
- Involvement of PI3K/Akt/TOR pathway in stretch-induced hypertrophy of myotubes
- (2009) Nobuaki Sasai et al. MUSCLE & NERVE
- Molecular mechanisms of mTOR-mediated translational control
- (2009) Xiaoju Max Ma et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Pharmacology of mTOR Inhibition
- (2009) D. A. Guertin et al. Science Signaling
- Rheumatoid cachexia: a complication of rheumatoid arthritis moves into the 21st century
- (2009) Ronenn Roubenoff ARTHRITIS RESEARCH & THERAPY
- Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
- (2009) Morris E Feldman et al. PLOS BIOLOGY
- The ubiquitin-proteasome and the mitochondria-associated apoptotic pathways are sequentially downregulated during recovery after immobilization-induced muscle atrophy
- (2008) Emilie Vazeille et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Attenuation of depression of muscle protein synthesis induced by lipopolysaccharide, tumor necrosis factor, and angiotensin II by β-hydroxy-β-methylbutyrate
- (2008) Helen L. Eley et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Resistance exercise decreases eIF2Bε phosphorylation and potentiates the feeding-induced stimulation of p70S6K1 and rpS6 in young men
- (2008) Elisa I. Glover et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Branched-chain amino acids and arginine suppress MaFbx/atrogin-1 mRNA expression via mTOR pathway in C2C12 cell line
- (2008) Elizabeth Henny Herningtyas et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy
- (2008) C. Florian Bentzinger et al. Cell Metabolism
- Amino Acids Activate mTOR Complex 1 via Ca2+/CaM Signaling to hVps34
- (2008) Pawan Gulati et al. Cell Metabolism
- Signal transduction pathways that regulate muscle growth
- (2008) Henning Wackerhage et al. Essays in Biochemistry
- Skeletal muscle proteolysis in response to short-term unloading in humans
- (2008) Per A. Tesch et al. JOURNAL OF APPLIED PHYSIOLOGY
- Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging
- (2008) Micah J. Drummond et al. JOURNAL OF APPLIED PHYSIOLOGY
- Maximal lengthening contractions induce different signaling responses in the type I and type II fibers of human skeletal muscle
- (2008) Jörgen Tannerstedt et al. JOURNAL OF APPLIED PHYSIOLOGY
- RalA Functions as an Indispensable Signal Mediator for the Nutrient-sensing System
- (2008) Tomohiko Maehama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle
- (2008) Sarah B. Wilkinson et al. JOURNAL OF PHYSIOLOGY-LONDON
- Intermittent Reloading Attenuates Muscle Atrophy through Modulating Akt/mTOR Pathway
- (2008) MITSUNORI MIYAZAKI et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Resistance Exercise Increases Postprandial Muscle Protein Synthesis in Humans
- (2008) OLIVER C. WITARD et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Body mass index, muscle and fat in chronic kidney disease: questions about survival
- (2008) D. Mafra et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle
- (2007) Hans C. Dreyer et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- A functional insulin-like growth factor receptor is not necessary for load-induced skeletal muscle hypertrophy
- (2007) Espen E. Spangenburg et al. JOURNAL OF PHYSIOLOGY-LONDON
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started