Microbial, host and xenobiotic diversity in the cystic fibrosis sputum metabolome

Essential genome ofPseudomonas aeruginosain cystic fibrosis sputum

(2015) Keith H. Turner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction

(2015) Christoph Tabeling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Untargeted Lipidomic Analysis in Chronic Obstructive Pulmonary Disease. Uncovering Sphingolipids

(2014) Eef D. Telenga et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pyrosequencing reveals transient cystic fibrosis lung microbiome changes with intravenous antibiotics

(2014) D. J. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

A Winogradsky-based culture system shows an association between microbial fermentation and cystic fibrosis exacerbation

(2014) Robert A Quinn et al.   ISME Journal

Breath gas metabolites and bacterial metagenomes from cystic fibrosis airways indicate active pH neutral 2,3-butanedione fermentation

(2014) Katrine L Whiteson et al.   ISME Journal

Time between Collection and Storage Significantly Influences Bacterial Sequence Composition in Sputum Samples from Cystic Fibrosis Respiratory Infections

(2014) L. Cuthbertson et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The Pseudomonas Toxin Pyocyanin Inhibits the Dual Oxidase-Based Antimicrobial System as It Imposes Oxidative Stress on Airway Epithelial Cells

(2014) B. Rada et al.   JOURNAL OF IMMUNOLOGY

A metabolic milieu

(2014) Sheilagh Molloy   NATURE REVIEWS MICROBIOLOGY

Biogeochemical Forces Shape the Composition and Physiology of Polymicrobial Communities in the Cystic Fibrosis Lung

(2014) R. A. Quinn et al.   mBio

Characterization and quantification of the fungal microbiome in serial samples from individuals with cystic fibrosis

(2014) Sven D Willger et al.   Microbiome

Integrated Metabolomics Approach Facilitates Discovery of an Unpredicted Natural Product Suite from Streptomyces coelicolor M145

(2013) Ashley M. Sidebottom et al.   ACS Chemical Biology

Ceramide and Cystic Fibrosis Lung Disease

(2013) Malcolm Brodlie et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ceramide mediates lung fibrosis in cystic fibrosis

(2013) Regan Ziobro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clinical Insights from Metagenomic Analysis of Sputum Samples from Patients with Cystic Fibrosis

(2013) Y. W. Lim et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Molecular Networking as a Dereplication Strategy

(2013) Jane Y. Yang et al.   JOURNAL OF NATURAL PRODUCTS

Inflammation and Airway Microbiota during Cystic Fibrosis Pulmonary Exacerbations

(2013) Edith T. Zemanick et al.   PLoS One

Phenotypic Heterogeneity of Pseudomonas aeruginosa Populations in a Cystic Fibrosis Patient

(2013) Matthew L. Workentine et al.   PLoS One

Rapid 16S rRNA Next-Generation Sequencing of Polymicrobial Clinical Samples for Diagnosis of Complex Bacterial Infections

(2013) Stephen J. Salipante et al.   PLoS One

Microbiota and Metabolite Profiling Reveal Specific Alterations in Bacterial Community Structure and Environment in the Cystic Fibrosis Airway during Exacerbation

(2013) Kate B. Twomey et al.   PLoS One

MS/MS networking guided analysis of molecule and gene cluster families

(2013) D. D. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ion mobility and liquid chromatography/mass spectrometry strategies for exhaled breath condensate glucose quantitation in cystic fibrosis studies

(2013) María Eugenia Monge et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Production of α-Galactosylceramide by a Prominent Member of the Human Gut Microbiota

(2013) Laura C. Wieland Brown et al.   PLOS BIOLOGY

Unique microbial communities persist in individual cystic fibrosis patients throughout a clinical exacerbation

(2013) Katherine E Price et al.   Microbiome

Phenazine Content in the Cystic Fibrosis Respiratory Tract Negatively Correlates with Lung Function and Microbial Complexity

(2012) Ryan C. Hunter et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Omics approaches in cystic fibrosis research: a focus on oxylipin profiling in airway secretions

(2012) Jason P. Eiserich et al.   Annals of the New York Academy of Sciences

Metabolic adaptations ofPseudomonas aeruginosaduring cystic fibrosis chronic lung infections

(2012) V. Behrends et al.   ENVIRONMENTAL MICROBIOLOGY

Metabolomic profiling of regulatory lipid mediators in sputum from adult cystic fibrosis patients

(2012) Jun Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Prevalence of Streptococci and Increased Polymicrobial Diversity Associated with Cystic Fibrosis Patient Stability

(2012) L. M. Filkins et al.   JOURNAL OF BACTERIOLOGY

Metagenomics and metatranscriptomics: Windows on CF-associated viral and microbial communities

(2012) Yan Wei Lim et al.   Journal of Cystic Fibrosis

Iron accumulates in the lavage and explanted lungs of cystic fibrosis patients

(2012) Andrew J. Ghio et al.   Journal of Cystic Fibrosis

The SILVA ribosomal RNA gene database project: improved data processing and web-based tools

(2012) Christian Quast et al.   NUCLEIC ACIDS RESEARCH

The Airway Microbiota in Cystic Fibrosis: A Complex Fungal and Bacterial Community—Implications for Therapeutic Management

(2012) Laurence Delhaes et al.   PLoS One

Analysis of the Cystic Fibrosis Lung Microbiota via Serial Illumina Sequencing of Bacterial 16S rRNA Hypervariable Regions

(2012) Heather Maughan et al.   PLoS One

Telomere length in early life predicts lifespan

(2012) B. J. Heidinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct sampling of cystic fibrosis lungs indicates that DNA-based analyses of upper-airway specimens can misrepresent lung microbiota

(2012) A. F. Goddard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interkingdom metabolic transformations captured by microbial imaging mass spectrometry

(2012) W. J. Moree et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decade-long bacterial community dynamics in cystic fibrosis airways

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-level over-expression, purification, and crystallization of a novel phospholipase C/sphingomyelinase from Pseudomonas aeruginosa

(2012) Daphné Truan et al.   PROTEIN EXPRESSION AND PURIFICATION

Quantitative Analysis of the Human Airway Microbial Ecology Reveals a Pervasive Signature for Cystic Fibrosis

(2012) P. C. Blainey et al.   Science Translational Medicine

Modulators of Sphingolipid Metabolism Reduce Lung Inflammation

(2011) Maria Cristina Dechecchi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Spatial distribution of microbial communities in the cystic fibrosis lung

(2011) Dana Willner et al.   ISME Journal

Proteomics of Pseudomonas aeruginosa Australian Epidemic Strain 1 (AES-1) Cultured under Conditions Mimicking the Cystic Fibrosis Lung Reveals Increased Iron Acquisition via the Siderophore Pyochelin

(2011) Nathan J. Hare et al.   JOURNAL OF PROTEOME RESEARCH

NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis

(2011) Paolo Montuschi et al.   THORAX

Metabolism and function of phenazines in bacteria: impacts on the behavior of bacteria in the environment and biotechnological processes

(2010) Leland S. Pierson et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Staphylococcus aureus sigma B-dependent emergence of small-colony variants and biofilm production following exposure to Pseudomonas aeruginosa 4-hydroxy-2-heptylquinoline-N-oxide

(2010) Gabriel Mitchell et al.   BMC MICROBIOLOGY

Adaptation of Pseudomonas aeruginosa during persistence in the cystic fibrosis lung

(2010) Michael Hogardt et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Phylogenetic and metabolic diversity of bacteria associated with cystic fibrosis

(2010) Adam M Guss et al.   ISME Journal

Lactate in cystic fibrosis sputum

(2010) Tobias Bensel et al.   Journal of Cystic Fibrosis

Critical Modifier Role of Membrane-Cystic Fibrosis Transmembrane Conductance Regulator-Dependent Ceramide Signaling in Lung Injury and Emphysema

(2010) M. Bodas et al.   JOURNAL OF IMMUNOLOGY

Gene expression of Pseudomonas aeruginosa in a mucin-containing synthetic growth medium mimicking cystic fibrosis lung sputum

(2010) C. Fung et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Oxygen levels rapidly modulate Pseudomonas aeruginosa social behaviours via substrate limitation of PqsH

(2010) Jeffrey W. Schertzer et al.   MOLECULAR MICROBIOLOGY

Metabolomics of Volatile Organic Compounds in Cystic Fibrosis Patients and Controls

(2010) Charlotte M H H T Robroeks et al.   PEDIATRIC RESEARCH

Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample

(2010) J. G. Caporaso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Introducing mothur: Open-Source, Platform-Independent, Community-Supported Software for Describing and Comparing Microbial Communities

(2009) P. D. Schloss et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolomic analysis of bronchoalveolar lavage fluid from cystic fibrosis patients

(2009) Justyna E. Wolak et al.   BIOMARKERS

Therapeutic Efficacy and Safety of Amitriptyline in Patients with Cystic Fibrosis

(2009) Joachim Riethmüller et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Instantaneous Within-Patient Diversity of Pseudomonas aeruginosa Quorum-Sensing Populations from Cystic Fibrosis Lung Infections

(2009) C. N. Wilder et al.   INFECTION AND IMMUNITY

Exhaled breath condensate pH and ammonia in cystic fibrosis and response to treatment of acute pulmonary exacerbations

(2009) Sharon Newport et al.   PEDIATRIC PULMONOLOGY

Metagenomic Analysis of Respiratory Tract DNA Viral Communities in Cystic Fibrosis and Non-Cystic Fibrosis Individuals

(2009) Dana Willner et al.   PLoS One

Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis

(2008) Paul M Quinton   LANCET

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

(2008) Volker Teichgräber et al.   NATURE MEDICINE

The Pseudomonas Quinolone Signal (PQS) Balances Life and Death in Pseudomonas aeruginosa Populations

(2008) Susanne Häussler et al.   PLoS Pathogens