A Winogradsky-based culture system shows an association between microbial fermentation and cystic fibrosis exacerbation

The Upper Respiratory Tract as a Microbial Source for Pulmonary Infections in Cystic Fibrosis. Parallels from Island Biogeography

(2014) Katrine L. Whiteson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Metabolite transfer with the fermentation product 2,3-butanediol enhances virulence by Pseudomonas aeruginosa

(2014) Arvind Venkataraman et al.   ISME Journal

Breath gas metabolites and bacterial metagenomes from cystic fibrosis airways indicate active pH neutral 2,3-butanedione fermentation

(2014) Katrine L Whiteson et al.   ISME Journal

Biogeochemical Forces Shape the Composition and Physiology of Polymicrobial Communities in the Cystic Fibrosis Lung

(2014) R. A. Quinn et al.   mBio

Cystic Fibrosis Therapy: A Community Ecology Perspective

(2013) Douglas Conrad et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Development of a Dual-Index Sequencing Strategy and Curation Pipeline for Analyzing Amplicon Sequence Data on the MiSeq Illumina Sequencing Platform

(2013) James J. Kozich et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Clinical Insights from Metagenomic Analysis of Sputum Samples from Patients with Cystic Fibrosis

(2013) Y. W. Lim et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Culture-based diagnostic microbiology in cystic fibrosis: Can we simplify the complexity?

(2013) Jane L. Burns et al.   Journal of Cystic Fibrosis

Shallow breathing: bacterial life at low O2

(2013) Rachel L. Morris et al.   NATURE REVIEWS MICROBIOLOGY

Inflammation and Airway Microbiota during Cystic Fibrosis Pulmonary Exacerbations

(2013) Edith T. Zemanick et al.   PLoS One

Mechanistic Model of Rothia mucilaginosa Adaptation toward Persistence in the CF Lung, Based on a Genome Reconstructed from Metagenomic Data

(2013) Yan Wei Lim et al.   PLoS One

Is the Improvement of CF Patients, Hospitalized for Pulmonary Exacerbation, Correlated to a Decrease in Bacterial Load?

(2013) Pieter Deschaght et al.   PLoS One

Microbiota and Metabolite Profiling Reveal Specific Alterations in Bacterial Community Structure and Environment in the Cystic Fibrosis Airway during Exacerbation

(2013) Kate B. Twomey et al.   PLoS One

Visualization of oxygen distribution patterns caused by coral and algae

(2013) Andreas F. Haas et al.   PeerJ

Unique microbial communities persist in individual cystic fibrosis patients throughout a clinical exacerbation

(2013) Katherine E Price et al.   Microbiome

Phenazine Content in the Cystic Fibrosis Respiratory Tract Negatively Correlates with Lung Function and Microbial Complexity

(2012) Ryan C. Hunter et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The cystic fibrosis airway microbiome

(2012) Harvey R. Rabin et al.   CURRENT OPINION IN PULMONARY MEDICINE

Intraclonal diversity of thePseudomonas aeruginosacystic fibrosis airway isolates TBCF10839 and TBCF121838: distinct signatures of transcriptome, proteome, metabolome, adherence and pathogenicity despite an almost identical genome sequence

(2012) Jens Klockgether et al.   ENVIRONMENTAL MICROBIOLOGY

Genomic Variation among Contemporary Pseudomonas aeruginosa Isolates from Chronically Infected Cystic Fibrosis Patients

(2012) Jade C. S. Chung et al.   JOURNAL OF BACTERIOLOGY

Iron accumulates in the lavage and explanted lungs of cystic fibrosis patients

(2012) Andrew J. Ghio et al.   Journal of Cystic Fibrosis

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

(2012) Alejandro A. Pezzulo et al.   NATURE

The SILVA ribosomal RNA gene database project: improved data processing and web-based tools

(2012) Christian Quast et al.   NUCLEIC ACIDS RESEARCH

The Airway Microbiota in Cystic Fibrosis: A Complex Fungal and Bacterial Community—Implications for Therapeutic Management

(2012) Laurence Delhaes et al.   PLoS One

The Adult Cystic Fibrosis Airway Microbiota Is Stable over Time and Infection Type, and Highly Resilient to Antibiotic Treatment of Exacerbations

(2012) Anthony A. Fodor et al.   PLoS One

Direct sampling of cystic fibrosis lungs indicates that DNA-based analyses of upper-airway specimens can misrepresent lung microbiota

(2012) A. F. Goddard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decade-long bacterial community dynamics in cystic fibrosis airways

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quality control and preprocessing of metagenomic datasets

(2011) R. Schmieder et al.   BIOINFORMATICS

The polymicrobial nature of airway infections in cystic fibrosis: Cangene Gold Medal LectureThis article is based on a presentation by Dr. Christopher Sibley at the 60th Annual Meeting of the Canadian Society of Microbiologists in Hamilton, Ontario, on 15 June 2010. Dr. Sibley was the recipient of the 2010 Cangene Gold Medal as the Canadian Graduate Student Microbiologist of the Year, an annual award sponsored by Cangene Corporation intended to recognize excellence in graduate research.

(2011) Christopher D. Sibley et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Clinical Significance of Microbial Infection and Adaptation in Cystic Fibrosis

(2011) A. R. Hauser et al.   CLINICAL MICROBIOLOGY REVIEWS

Microbial ecology and adaptation in cystic fibrosis airways

(2011) Lei Yang et al.   ENVIRONMENTAL MICROBIOLOGY

Spatial distribution of microbial communities in the cystic fibrosis lung

(2011) Dana Willner et al.   ISME Journal

Does bacterial density in cystic fibrosis sputum increase prior to pulmonary exacerbation?

(2011) Franziska A. Stressmann et al.   Journal of Cystic Fibrosis

Proteomics of Pseudomonas aeruginosa Australian Epidemic Strain 1 (AES-1) Cultured under Conditions Mimicking the Cystic Fibrosis Lung Reveals Increased Iron Acquisition via the Siderophore Pyochelin

(2011) Nathan J. Hare et al.   JOURNAL OF PROTEOME RESEARCH

Exacerbation frequency and clinical outcomes in adult patients with cystic fibrosis

(2011) K. de Boer et al.   THORAX

Staphylococcus aureus sigma B-dependent emergence of small-colony variants and biofilm production following exposure to Pseudomonas aeruginosa 4-hydroxy-2-heptylquinoline-N-oxide

(2010) Gabriel Mitchell et al.   BMC MICROBIOLOGY

The exclusion of dead bacterial cells is essential for accurate molecular analysis of clinical samples

(2010) G.B. Rogers et al.   CLINICAL MICROBIOLOGY AND INFECTION

The Changing Microbial Epidemiology in Cystic Fibrosis

(2010) J. J. LiPuma   CLINICAL MICROBIOLOGY REVIEWS

How Pseudomonas aeruginosa adapts to various environments: a metabolomic approach

(2010) Eliane Frimmersdorf et al.   ENVIRONMENTAL MICROBIOLOGY

Anaerobic physiology of Pseudomonas aeruginosa in the cystic fibrosis lung

(2010) Max Schobert et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Adaptation of Pseudomonas aeruginosa during persistence in the cystic fibrosis lung

(2010) Michael Hogardt et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Gene expression of Pseudomonas aeruginosa in a mucin-containing synthetic growth medium mimicking cystic fibrosis lung sputum

(2010) C. Fung et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample

(2010) J. G. Caporaso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibiotic-resistant obligate anaerobes during exacerbations of cystic fibrosis patients

(2009) D. Worlitzsch et al.   CLINICAL MICROBIOLOGY AND INFECTION

Effect of oxygen limitation on the in vitro activity of levofloxacin and other antibiotics administered by the aerosol route against Pseudomonas aeruginosa from cystic fibrosis patients

(2009) Paula King et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Acetaldehyde and hexanaldehyde from cultured white cells

(2009) Hye-Won Shin et al.   Journal of Translational Medicine

Pseudomonas aeruginosabiofilms in the respiratory tract of cystic fibrosis patients

(2009) Thomas Bjarnsholt et al.   PEDIATRIC PULMONOLOGY

Metagenomic Analysis of Respiratory Tract DNA Viral Communities in Cystic Fibrosis and Non-Cystic Fibrosis Individuals

(2009) Dana Willner et al.   PLoS One

Detection of Anaerobic Bacteria in High Numbers in Sputum from Patients with Cystic Fibrosis

(2008) Michael M. Tunney et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A polymicrobial perspective of pulmonary infections exposes an enigmatic pathogen in cystic fibrosis patients

(2008) C. D. Sibley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA