Article
Food Science & Technology
Leyla Sanhueza, Paula Garcia, Begona Gimenez, Jose Manuel Benito, Maria Matos, Gemma Gutierrez
Summary: The feasibility of encapsulating pomegranate peel extract in double emulsions was evaluated, and double emulsions prepared by direct membrane emulsification showed better stability and encapsulation efficiency.
Review
Ophthalmology
Ying Chen, Victoria R. Kearns, Liangyu Zhou, Teresa Sandinha, Wai Ching Lam, David H. Steel, Yau Kei Chan
Summary: This review provides an overview of the use of silicone oil as a long-term tamponade agent in the treatment of complicated vitreoretinal diseases. It covers the chemical and physical properties of silicone oil, its indications and complications, particularly emulsification, as well as the mechanisms and risk factors for emulsification and strategies for its effective removal. The review also explores new formulations of silicone oil, including research into slow-release pharmacological agents within silicone oil, and alternatives being developed for long-term tamponade.
ACTA OPHTHALMOLOGICA
(2021)
Article
Medicine, General & Internal
Leyi Wang, Xin Wang, Xuepeng Yang, Yuanyuan Si, Jiayin Wu, Yan Cui
Summary: In this study, a theoretical formula for calculating intraocular lens power for silicone oil-dependent eyes was deduced and compared with clinical findings. The results showed no significant difference between the theoretical and clinical refractive powers, indicating a strong correlation between them.
FRONTIERS IN MEDICINE
(2023)
Article
Ophthalmology
Maximilian Hammer, Sonja Schickhardt, Donald J. Munro, Alexander Scheuerle, Christian S. Mayer, Gerd U. Auffarth
Summary: The study showed that prolonged exposure to hydrophilic biological media does not alter the physicochemical parameters of high-viscosity silicone oil, while the addition of high-molecular-weight components may decrease the oil's electrochemical emulsion stability.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2022)
Article
Ophthalmology
Tibor Lohmann, Hendrik Schwarzer, Antonis Koutsonas, Yassin Djalali-Talab, Matthias Fuest, Randolf A. Widder, Peter Walter, Gernot Roessler
Summary: This study found that secondary surgery with heavy silicone oil tamponade is a safe and efficient method for treating persistent full-thickness macular holes. Best-corrected visual acuity and minimum linear diameter before surgery may serve as indicators for anatomical success.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2022)
Article
Chemistry, Physical
Douglas Rodrigues Reis, Guilherme Zin, Elenara Lemos-Senna, Alan Ambrosi, Marco Di Luccio
Summary: A versatile and innovative membrane emulsification system was studied for preparing oil/water emulsions from spearmint essential oil, utilizing a modified premix method known as forced-air premix (FAP). The FAP method, compared to traditional premix method, showed early shearing and detachment of oil droplets influenced by airflow velocity. Operating pressure increase resulted in reduced droplet size and span values, and higher surfactant concentration and forced airflow in FAP method influenced droplet size reduction and emulsion dispersion. Stable emulsions were obtained after 28 days of storage.
SURFACES AND INTERFACES
(2021)
Review
Food Science & Technology
Mayumi Silva, Jayani Chandrapala
Summary: Ultrasound-assisted emulsification is an emerging technology that can be used to prepare stable primary and double emulsions. This review discusses the factors affecting milk protein stabilization under sono-emulsification.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Chemistry, Multidisciplinary
Seon-Ae Hwangbo, Seung-Yul Lee, Bu-An Kim, Chang-Kwon Moon
Summary: This paper presents an efficient method for surfactant-free nano-emulsification and discusses the effects of different operating parameters and particle size on emulsion stability. The focused ultrasonic system showed the best performance, producing stable nano-emulsions with a small particle size distribution.
Article
Chemistry, Applied
Takashi Kuroiwa, Shiho Hamada
Summary: This study investigated the effect of an interfacial polyelectrolyte complex layer on the stability of multiple water-in-oil-in-water (W/O/W) emulsions containing palm oil. The results showed that the formation of a chitosan-sodium caseinate complex layer at the oil-water interface could suppress the aggregation of the multiple droplets, even below the crystallization temperature of palm oil. The presence of the polyelectrolyte complex layer also improved the droplet dispersibility and encapsulation efficiency of the multiple droplets during heating and cooling.
FOOD HYDROCOLLOIDS
(2023)
Review
Food Science & Technology
Lingxi Guo, Liuping Fan, Yuanfa Liu, Jinwei Li
Summary: Functional oil is a beneficial and nutritionally valuable oil, but its bioactive substances, such as polyunsaturated fatty acids, are sensitive to environmental factors and prone to oxidation or decomposition. Emulsion-based oil powder construction is a promising method for improving the stability and solubility of functional oils. However, the low effective loading of oil in powder is currently a major challenge. This manuscript reviews the research progress of emulsion-based functional oil powder construction, summarizes the processing characteristics of high payload emulsion-based oil powder, and discusses strategies for enhancing powder payload through emulsification and drying.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Food Science & Technology
Xin Ying, Jiaxing Gao, Jing Lu, Changlu Ma, Jiaping Lv, Benu Adhikari, Bo Wang
Summary: In this study, soy peptide solution was successfully encapsulated in a W-1/O/W-2 double emulsion using PGPR as an effective inner emulsifier. The droplet size and encapsulation efficiency of the peptide solution depended on various factors including the ratio and concentration of phases. The freeze-dried microcapsule powder showed higher encapsulation efficiency compared to spray-dried one, indicating the potential of this double emulsion as a delivery matrix for hydrophilic ingredients.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Ophthalmology
Hongmei Zhao, Tongjie Cheng, Kaicheng Wu, Jian Yu, Yuan Zong, Qian Chen, Chunhui Jiang, Haohao Zhu, Gezhi Xu
Summary: This study investigated the presence of residual emulsified silicone oil droplets in patients with rhegmatogenous retinal detachment (RRD) and explored their possible risk factors. The results showed that residual silicone oil particles were found in all patients, and the presence of these particles was positively correlated with axial length and ocular hypertension. The findings provide guidance for the treatment of these patients.
Article
Multidisciplinary Sciences
Machiko Shimmura-Tomita, Hiroko Takano, Yoshiaki Tanaka, Rina Takagi, Toshikatsu Kaburaki, Akihiro Kakehashi
Summary: This study investigated the impact of silicone oil presence in the anterior chamber on corneal endothelium damage following pars plana vitrectomy. The results showed a high correlation between the retention period of silicone oil tamponade and the decrease rate of corneal endothelial cell density. However, there was no correlation between the presence of anterior chamber silicone oil, area of silicone oil attachment, lens status, and the decrease rate of corneal endothelial cell density.
SCIENTIFIC REPORTS
(2021)
Article
Energy & Fuels
Clara Delgado-Sanchez, Pedro Partal, Maria Jose Martin-Alfonso, Francisco Javier Navarro
Summary: Non-aqueous phase change emulsions are promising multifunctional fluids composed of phase change materials dispersed in carrier fluids. This paper presents the development of stable emulsions using stearic acid and silicone oil, and evaluates their properties and stability. The results demonstrate that these emulsions have the potential to be used for both latent heat storage and transport under extreme conditions.
SOLAR ENERGY MATERIALS AND SOLAR CELLS
(2022)
Review
Chemistry, Multidisciplinary
Lian Xiaodong, Song Chenhao, Wang Yapei
Summary: Double emulsions have been widely used due to their multiple phases. However, constructing droplets with such a complex structure is not an easy task. Over the past century, scientists have made great efforts in both theory and preparation of double emulsions. This review systematically reveals the current understanding and discusses the state-of-the-art achievements in double emulsions.
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
(2022)
Article
Materials Science, Biomaterials
Lap Tak Hung, Stephanie Hiu Ling Poon, Wing Huen Yan, Rebecca Lace, Liangyu Zhou, Jasper Ka Wai Wong, Rachel L. Williams, Kendrick Co Shih, Ho Cheung Shum, Yau Kei Chan
Summary: A strategy using a biocompatible polymer-based liquid-liquid interface has been developed for the rapid fabrication of scaffold-free corneal tissue constructs. The formed constructs exhibit essential physiological markers, preserved viability and proliferative ability, and can repair corneal epithelial wounds in vitro.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2022)
Article
Multidisciplinary Sciences
Yi Pan, Zhenyu Yang, Chang Li, Sammer Ul Hassan, Ho Cheung Shum
Summary: The healthy functioning of plants' vasculature relies on their ability to respond to environmental changes. Inspired by the way plants respond to environmental stimuli, researchers have developed a transformable microfluidic device that can respond to temperature, humidity, and light irradiance. By incorporating stimuli-responsive materials and a foldable geometry, this device can undergo responsive movements similar to origami transformations. It has been named TransfOrigami microfluidics (TOM) to emphasize its transformation and origami structure. TOM can be used as an environmentally adaptive photomicroreactor, which senses environmental stimuli and utilizes morphological transformation to enhance photosynthetic conversion. This concept of a morphable microsystem has the potential to be applied in various fields that require responsiveness between the environment and devices, such as dynamic artificial vascular networks and shape-adaptive flexible electronics.
Article
Chemistry, Applied
Yijie Wang, Xiufeng Li, Ting Li, Yang Wang, Jie Jiang, Xuhui Zhang, Jing Huang, Bihua Xia, Ho Cheung Shum, Zhenzhong Yang, Weifu Dong
Summary: A chemical approach is used to fabricate particles by combining a water-insoluble plant protein and a hydrophilic polysaccharide, resulting in adjustable interfacial wettability and improved absorption kinetics for emulsions.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Multidisciplinary
Wei Guo, Danyang Ji, Andrew B. Kinghorn, Feipeng Chen, Yi Pan, Xiufeng Li, Qingchuan Li, Wilhelm T. S. Huck, Chun Kit Kwok, Ho Cheung Shum
Summary: RNA encodes interactions to modulate the properties of biomolecular condensates, and rG4s formed by guanine-rich sequences can trigger the formation of these condensates. The mechanisms by which rG4 motifs modulate phase transitions and material properties of condensates are unclear.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Biochemical Research Methods
Fang Wang, Chang Li, Ruotong Zhang, Yuan Liu, Haisong Lin, Lang Nan, Muhammad Ajmal Khan, Yang Xiao, Ho Cheung Shum, Hui Deng
Summary: Cold atmospheric plasma chip enables targeted and multi-dosage treatment of multiple cell lines in a single session. This innovative approach provides a new tool for investigating the mechanisms of plasma-induced anticancer effects and guiding clinical applications.
Article
Chemistry, Multidisciplinary
Shi Yang, Han Yu, Xiuli Xu, Ting Yang, Yue Wei, Rui Zan, Xiaonong Zhang, Qingming Ma, Ho Cheung Shum, Yang Song
Summary: This article presents the synthesis of a peptide-based RNA sensor by connecting aggregation-induced emission luminogen (AIEgen) tetraphenylethylene (TPE) to tandem peptide repeats of (RRASL)n (n = 1, 2, 3). The conjugation of TPE promotes liquid-liquid phase separation of the peptide repeats, with significantly decreased minimum coacervation concentration (MCC) compared to the untagged counterparts. Furthermore, the luminescence of TPE-(RRASL)n is greatly enhanced with increasing RNA concentration, attributed to the constricted rotation of the TPE moiety within the droplet phase formed by peptide/RNA coacervates. In addition, TPE-(RRASL)n can efficiently penetrate human gallbladder carcinoma cells, translocate into the nucleus, and colocalize with intracellular RNA, highlighting its potential as a droplet-based biosensor for intracellular RNA imaging.
Article
Chemistry, Multidisciplinary
Chang Li, Yafeng Yu, Huizeng Li, Haisong Lin, Huanqing Cui, Yi Pan, Ruotong Zhang, Yanlin Song, Ho Cheung Shum
Summary: The heterogeneous self-assembly of a single type of nanoparticle is achieved by quickly evaporating a colloid-poly(ethylene glycol) (PEG) droplet, facilitated by the spatial confinement induced by a skin layer. This approach allows for the formation of face-centered-cubic (FCC) lattices with different plane orientations, generating binary bandgaps and structural colors. The self-assembly of nanoparticles can be regulated by adjusting the PEG concentration, and the method is applicable to various droplet shapes, substrates, and nanoparticle types.
Article
Chemistry, Multidisciplinary
Yanting Shen, Yuan Liu, Janine K. Nunes, Chenmin Wang, Miao Xu, Michael K. T. To, Howard A. Stone, Ho Cheung Shum
Summary: Injectable fibro-gel, a water-filled network of entangled hydrogel microfibers, has shown great potential in tissue engineering and regenerative medicine due to its injectability, tailorable physicochemical properties, and controlled drug release profiles. Preliminary in vivo tests on a mice excision skin model have demonstrated that the fibro-gel promotes faster wound healing and new tissue regeneration compared to a commercial gel. Moreover, the release of distinct drugs at different rates using a two-layer fibro-gel model further enhances wound healing efficiency.
ADVANCED MATERIALS
(2023)
Article
Multidisciplinary Sciences
Zehao Pan, Janine K. Nunes, Camille Duprat, Ho Cheung Shum, Howard A. Stone
Summary: When a suspension of particles passes through a constriction, the particle volume fraction either decreases or remains unchanged. However, an entangled fiber suspension can increase its volume fraction by over 10 times after passing through a constriction. This increase is attributed to the entanglements among the fibers, which allow the network to move faster than the liquid. This finding provides a new strategy to control soft material properties during delivery processes in healthcare, 3D printing, and material repair.
NATURE COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Feipeng Chen, Xiufeng Li, Yafeng Yu, Qingchuan Li, Haisong Lin, Lizhi Xu, Ho Cheung Shum
Summary: The authors present a one-step fabrication method based on aqueous phase separation to construct two-aqueous-phase gels with multiple phases. These gels exhibit enhanced interfacial mechanics and can be conveniently constructed with programmable structures and tunable properties. The versatility of this approach is demonstrated by mimicking various biological architecture features at different length scales.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Yi Pan, Chang Li, Xiaoyu Hou, Zhenyu Yang, Mingzhu Li, Ho Cheung Shum
Summary: The challenge of achieving individually and independently programmable stimuli-responsive color pixels in color-changing soft materials and devices has been addressed by designing a morphable concavity array on a two-dimensional photonic crystal elastomer. By using multichannel microfluidics, the colors of each concavity can be switched controllably, enabling dynamic display for applications such as anti-counterfeiting and encryption.
Article
Chemistry, Multidisciplinary
Bin Li, Weizhong Yang, Rui Shu, Hang Yang, Fan Yang, Wenyu Dai, Wanxi Chen, Yau Kei Chan, Ding Bai, Yi Deng
Summary: A bio-heterojunction platform composed of CuS/MXene and a VEGF-mimicking peptide (VMP) is developed for infectious wound regeneration through an endogenous-exogenous bistimulatory angiogenic strategy. The platform exhibits versatile effects including photothermal, photodynamic, and chemodynamic effects for antibacterial efficacy. Copper ions released from the platform elevate VEGF secretion, which activates VEGF receptors through the endogenous pathway, while VMP promotes endothelial cell multiplication and tube formation through the exogenous pathway. In vivo experiments confirm that this strategy considerably boosts cutaneous regeneration by eliminating pathogens, promoting angiogenesis, and inducing collagen deposition.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Yixuan Huang, Shuai He, Sheng Yu, Hannah M. Johnson, Yau Kei Chan, Zheng Jiao, Shouteng Wang, Zixiang Wu, Yi Deng
Summary: This study presents a decorated nanofibrous membrane that can generate local heat and elevate reactive oxygen species (ROS) levels for effective bacterial eradication through photothermal/photodynamic effects. The membrane loaded with aspirin exhibits good cytocompatibility, enhances cell growth, and suppresses the NF-& kappa;B pathway, showing excellent anti-inflammatory effects. In vivo investigations confirm that the nanofibrous membrane accelerates infectious cutaneous regeneration by killing bacteria, promoting collagen deposition, boosting angiogenesis, and dampening inflammatory reaction through the NF-& kappa;B pathway.
Review
Chemistry, Multidisciplinary
Yan Zhan, Chang Li, Zhigang Che, Ho Cheung Shum, Xiaotian Hu, Huizeng Li
Summary: Benefiting from their superior photophysical properties and low-cost crystalline substances, perovskites have emerged as competitive photoactive semiconductors for optoelectronic devices. Photon management is crucial for perovskites due to their direct band gap and high refractive index. Photonic structures with periodic features offer efficient means to manage light through the interaction between media and photons. This review discusses strategies of photon management in perovskite optoelectronics and summarizes the design and implementation progress of photonic elements for high-index perovskites. Proposals and guidelines for high-performance multifunctional perovskite optoelectronics are also provided.
ENERGY & ENVIRONMENTAL SCIENCE
(2023)
Article
Chemistry, Physical
Niki Abbasi, Janine K. Nunes, Zehao Pan, Tejas Dethe, Ho Cheung Shum, Andrej Kosmrlj, Howard A. Stone
Summary: Liquid-liquid phase separation induced by co-flow of a nonequilibrated aqueous two-phase system within a planar flow-focusing microfluidic device is experimentally demonstrated. Invasion fronts from the outer stream are formed along the top and bottom walls of the microfluidic device, which merge as the system reaches steady-state. The formation and growth of the invasion fronts are driven by Marangoni flow induced by the polymer concentration gradient along the width of the channel during phase separation.