Metabolism of Oxo-Bile Acids and Characterization of Recombinant 12α-Hydroxysteroid Dehydrogenases from Bile Acid 7α-Dehydroxylating Human Gut Bacteria

Identification of a gene encoding a flavoprotein involved in bile acid metabolism by the human gut bacterium Clostridium scindens ATCC 35704

(2018) Spencer C. Harris et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Microbial modulation of cardiovascular disease

(2018) J. Mark Brown et al.   NATURE REVIEWS MICROBIOLOGY

Targeted Synthesis and Characterization of a Gene Cluster Encoding NAD(P)H-Dependent 3α-, 3β-, and 12α-Hydroxysteroid Dehydrogenases from Eggerthella CAG:298, a Gut Metagenomic Sequence

(2018) Sean M. Mythen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Comprehensive evaluation of the bactericidal activities of free bile acids in the large intestine of humans and rodents

(2017) Masamichi Watanabe et al.   JOURNAL OF LIPID RESEARCH

Ursodeoxycholic Acid in the Prevention of Gallstone Formation After Bariatric Surgery: an Updated Systematic Review and Meta-analysis

(2017) Dimitrios E. Magouliotis et al.   OBESITY SURGERY

Ursodeoxycholic acid inhibits the proliferation of colon cancer cells by regulating oxidative stress and cancer stem-like cell growth

(2017) Eun-Kyung Kim et al.   PLoS One

Rapid analysis of bile acids in different biological matrices using LC-ESI-MS/MS for the investigation of bile acid transformation by mammalian gut bacteria

(2016) Katrin Wegner et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Bile acids and their oxo derivatives: Potential inhibitors of carbonic anhydrase I and II, androgen receptor antagonists and CYP3A4 substrates

(2016) Jovana Trifunović et al.   BIOMEDICAL CHROMATOGRAPHY

Structure and functional characterization of a bile acid 7α dehydratase BaiE in secondary bile acid synthesis

(2016) Shiva Bhowmik et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A biosynthetic pathway for a prominent class of microbiota-derived bile acids

(2015) A Sloan Devlin et al.   Nature Chemical Biology

In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids

(2014) Sui Peng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Correlation Between Intraluminal Oxygen Gradient and Radial Partitioning of Intestinal Microbiota

(2014) Lindsey Albenberg et al.   GASTROENTEROLOGY

Intestinal transport and metabolism of bile acids

(2014) Paul A. Dawson et al.   JOURNAL OF LIPID RESEARCH

A simple and accurate HPLC method for fecal bile acid profile in healthy and cirrhotic subjects: validation by GC-MS and LC-MS

(2014) Genta Kakiyama et al.   JOURNAL OF LIPID RESEARCH

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Structural and functional characterization of BaiA, an enzyme involved in secondary bile acid synthesis in human gut microbe

(2013) Shiva Bhowmik et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Dendroscope 3: An Interactive Tool for Rooted Phylogenetic Trees and Networks

(2012) Daniel H. Huson et al.   SYSTEMATIC BIOLOGY

Carcinogenicity of deoxycholate, a secondary bile acid

(2011) Carol Bernstein et al.   ARCHIVES OF TOXICOLOGY

Identification and characterization of two bile acid coenzyme A transferases fromClostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium

(2011) Jason M. Ridlon et al.   JOURNAL OF LIPID RESEARCH

Hydroxysteroid dehydrogenases (HSDs) in bacteria – A bioinformatic perspective

(2011) Michael Kisiela et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

(2010) Morgan N. Price et al.   PLoS One

Isolation and characterization of a bile acid inducible 7α-dehydroxylating operon in Clostridium hylemonae TN271

(2009) Jason M. Ridlon et al.   ANAEROBE

Deoxycholic acid induces the overexpression of intestinal mucin, MUC2, via NF-kB signaling pathway in human esophageal adenocarcinoma cells

(2008) JianTao Wu et al.   BMC CANCER

Faecal steroid excretion in humans is affected by calcium supplementation and shows gender-specific differences

(2008) Bianka Ditscheid et al.   EUROPEAN JOURNAL OF NUTRITION

Adlercreutzia equolifaciens gen. nov., sp. nov., an equol-producing bacterium isolated from human faeces, and emended description of the genus Eggerthella

(2008) T. Maruo et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome

(2008) B. V. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA