Cell-Death-Associated Molecular Patterns As Determinants of Cancer Immunogenicity

Cancer-Associated Fibroblasts and Their Putative Role in Potentiating the Initiation and Development of Epithelial Ovarian Cancer

(2015) Isaiah G. Schauer et al.   NEOPLASIA

Maturing Dendritic Cells Depend on RAGE for In Vivo Homing to Lymph Nodes

(2014) A. A. Manfredi et al.   JOURNAL OF IMMUNOLOGY

Pharmacological targeting of endoplasmic reticulum stress signaling in cancer

(2012) Axel H. Schönthal   BIOCHEMICAL PHARMACOLOGY

p53/HMGB1 Complexes Regulate Autophagy and Apoptosis

(2012) K. M. Livesey et al.   CANCER RESEARCH

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells

(2012) Susan Ahrens et al.   IMMUNITY

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

(2012) Emilie Venereau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Overexpression of CD73 in epithelial ovarian carcinoma is associated with better prognosis, lower stage, better differentiation and lower regulatory T cell infiltration

(2012) Hoon Kyu Oh et al.   Journal of Gynecologic Oncology

High expression of CD73 as a poor prognostic biomarker in human colorectal cancer

(2012) Xian-Rui Wu et al.   JOURNAL OF SURGICAL ONCOLOGY

Inflammasomes in carcinogenesis and anticancer immune responses

(2012) Laurence Zitvogel et al.   NATURE IMMUNOLOGY

Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

(2012) Shigeki Chiba et al.   NATURE IMMUNOLOGY

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

ENTPD1/CD39 is a promising therapeutic target in oncology

(2012) J Bastid et al.   ONCOGENE

Combination of glycolysis inhibition with chemotherapy results in an antitumor immune response

(2012) M. Beneteau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death

(2012) L. Menger et al.   Science Translational Medicine

Can the exome and the immunome converge on the design of efficient cancer vaccines?

(2012) Guido Kroemer et al.   OncoImmunology

CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death

(2011) S. Serra et al.   BLOOD

Novel Toll-like receptor-4 deficiency attenuates trastuzumab (Herceptin) induced cardiac injury in mice

(2011) Nasser Ghaly Yousif et al.   BMC Cardiovascular Disorders

Effective antibody therapy induces host-protective antitumor immunity that is augmented by TLR4 agonist treatment

(2011) Shangzi Wang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity

(2011) Sebastian F. M. Häusler et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Pivotal Role of Innate and Adaptive Immunity in Anthracycline Chemotherapy of Established Tumors

(2011) S. R. Mattarollo et al.   CANCER RESEARCH

Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response

(2011) J. Fucikova et al.   CANCER RESEARCH

IL-18 Induces PD-1-Dependent Immunosuppression in Cancer

(2011) M. Terme et al.   CANCER RESEARCH

CD73-Deficient Mice Have Increased Antitumor Immunity and Are Resistant to Experimental Metastasis

(2011) J. Stagg et al.   CANCER RESEARCH

Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy

(2011) N. Halama et al.   CANCER RESEARCH

CD39 Expression on T Lymphocytes Correlates With Severity of Disease in Patients With Chronic Lymphocytic Leukemia

(2011) Dianne Pulte et al.   Clinical Lymphoma Myeloma & Leukemia

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

(2011) Yuting Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival

(2011) Sylvain Ladoire et al.   JOURNAL OF PATHOLOGY

CD73 (5′-nucleotidase) expression has no prognostic value in children with acute lymphoblastic leukemia

(2011) E Wieten et al.   LEUKEMIA

Constitutive Aberrant Endogenous Interleukin-1 Facilitates Inflammation and Growth in Human Melanoma

(2011) Y. Qin et al.   MOLECULAR CANCER RESEARCH

Leukocyte composition of human breast cancer

(2011) B. Ruffell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of CD39 and purinergic signalling on the growth and metastasis of colorectal cancer

(2011) Beat M. Künzli et al.   Purinergic Signalling

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

(2011) David G. DeNardo et al.   Cancer Discovery

The Therapeutic Effect of Anti-HER2/neu Antibody Depends on Both Innate and Adaptive Immunity

(2010) SaeGwang Park et al.   CANCER CELL

The Inflammasome Component Nlrp3 Impairs Antitumor Vaccine by Enhancing the Accumulation of Tumor-Associated Myeloid-Derived Suppressor Cells

(2010) H. W. van Deventer et al.   CANCER RESEARCH

Improved Clinical Outcome in Indolent B-Cell Lymphoma Patients Vaccinated with Autologous Tumor Cells Experiencing Immunogenic Death

(2010) R. Zappasodi et al.   CANCER RESEARCH

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Decoding Cell Death Signals in Inflammation and Immunity

(2010) Laurence Zitvogel et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Chemotherapy induces ATP release from tumor cells

(2010) Isabelle Martins et al.   CELL CYCLE

Immune Regulation of Cancer

(2010) Mary L. Disis   JOURNAL OF CLINICAL ONCOLOGY

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages

(2010) Fabio Martinon et al.   NATURE IMMUNOLOGY

Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress

(2010) I Martins et al.   ONCOGENE

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

(2010) M. P. Chao et al.   Science Translational Medicine

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Lymphopenia as a Prognostic Factor for Overall Survival in Advanced Carcinomas, Sarcomas, and Lymphomas

(2009) Isabelle Ray-Coquard et al.   CANCER RESEARCH

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

(2009) Theocharis Panaretakis et al.   EMBO JOURNAL

Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β

(2009) Miyako Okamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor-Associated Lymphocytes As an Independent Predictor of Response to Neoadjuvant Chemotherapy in Breast Cancer

(2009) Carsten Denkert et al.   JOURNAL OF CLINICAL ONCOLOGY

Induction of a Chronic Disease State in Patients With Smoldering or Indolent Multiple Myeloma by Targeting Interleukin 1β-Induced Interleukin 6 Production and the Myeloma Proliferative Component

(2009) John A. Lust et al.   MAYO CLINIC PROCEEDINGS

Metastasis-related Plasma Membrane Proteins of Human Breast Cancer Cells Identified by Comparative Quantitative Mass Spectrometry

(2009) Rikke Leth-Larsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

(2009) David Sancho et al.   NATURE

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Immunogenic death of colon cancer cells treated with oxaliplatin

(2009) A Tesniere et al.   ONCOGENE

Immune infiltration in human tumors: a prognostic factor that should not be ignored

(2009) F Pagès et al.   ONCOGENE

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of Interleukin-1β Induces Gastric Inflammation and Cancer and Mobilizes Myeloid-Derived Suppressor Cells in Mice

(2008) Shuiping Tu et al.   CANCER CELL

The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death

(2008) T Panaretakis et al.   CELL DEATH AND DIFFERENTIATION

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

E-selectin regulates gene expression in metastatic colorectal carcinoma cells and enhances HMGB1 release

(2008) Tegest Aychek et al.   INTERNATIONAL JOURNAL OF CANCER

The anticancer immune response: indispensable for therapeutic success?

(2008) Laurence Zitvogel et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

(2008) David Sancho et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of Chemoradiation on Tumor-Host Interactions: The Immunologic Side

(2008) Silvia C. Formenti et al.   JOURNAL OF CLINICAL ONCOLOGY

Cancer as an overhealing wound: an old hypothesis revisited

(2008) Matthias Schäfer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cancer Immunology

(2008) Olivera J. Finn   NEW ENGLAND JOURNAL OF MEDICINE