Molecular Controls of the Oxygenation and Redox Reactions of Hemoglobin

N-acetylcysteine reduces oxidative stress in sickle cell patients

(2012) Erfan Nur et al.   ANNALS OF HEMATOLOGY

Haptoglobin Binding Stabilizes Hemoglobin Ferryl Iron and the Globin Radical on Tyrosine β145

(2012) Chris E. Cooper et al.   ANTIOXIDANTS & REDOX SIGNALING

Haptoglobin alters oxygenation and oxidation of hemoglobin and decreases propagation of peroxide-induced oxidative reactions

(2012) Sambuddha Banerjee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy

(2012) Jin Hyen Baek et al.   JOURNAL OF CLINICAL INVESTIGATION

A “Sliding Scale Rule” for Selectivity among NO, CO, and O2 by Heme Protein Sensors

(2011) Ah-Lim Tsai et al.   BIOCHEMISTRY

Steric factors moderate conformational fluidity and contribute to the high proton sensitivity of Root effect hemoglobins

(2011) Celia Bonaventura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Sickle Hemoglobin Confers Tolerance to Plasmodium Infection

(2011) Ana Ferreira et al.   CELL

Hemoglobins S and C Interfere with Actin Remodeling in Plasmodium falciparum-Infected Erythrocytes

(2011) M. Cyrklaff et al.   SCIENCE

Reconstructing sickle cell disease: A data-based analysis of the “hyperhemolysis paradigm” for pulmonary hypertension from the perspective of evidence-based medicine

(2010) Robert P. Hebbel   AMERICAN JOURNAL OF HEMATOLOGY

Mechanisms of Cell Protection by Heme Oxygenase-1

(2010) Raffaella Gozzelino et al.   Annual Review of Pharmacology and Toxicology

The Redox Activity of Hemoglobins: From Physiologic Functions to Pathologic Mechanisms

(2010) Brandon J. Reeder   ANTIOXIDANTS & REDOX SIGNALING

Blood Aging, Safety, and Transfusion: Capturing the “Radical” Menace

(2010) Paul W. Buehler et al.   ANTIOXIDANTS & REDOX SIGNALING

Red Cells, Hemoglobin, Heme, Iron, and Atherogenesis

(2010) Emőke Nagy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Structure and Properties of a Bis-Histidyl Ligated Globin fromCaenorhabditis elegans,

(2010) Jungjoo Yoon et al.   BIOCHEMISTRY

Extreme differences between Hemoglobins I and II of the Clam Lucina pectinalis in their reactions with nitrite

(2010) Celia Bonaventura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Pulmonary hypertension and nitric oxide depletion in sickle cell disease

(2010) H. F. Bunn et al.   BLOOD

Haptoglobin: Old protein with new functions

(2010) Abdu I. Alayash   CLINICA CHIMICA ACTA

Setbacks in Blood Substitutes Research and Development: A Biochemical Perspective

(2010) Abdu I. Alayash   CLINICS IN LABORATORY MEDICINE

Peroxynitrite stress is exacerbated by flavohaemoglobin-derived oxidative stress in Salmonella Typhimurium and is relieved by nitric oxide

(2010) S. McLean et al.   MICROBIOLOGY-SGM

Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglobin from peroxidative modification

(2009) P. W. Buehler et al.   BLOOD

Bacterial nitric oxide detoxification prevents host cell S-nitrosothiol formation: a novel mechanism of bacterial pathogenesis

(2009) Jay R. Laver et al.   FASEB JOURNAL

Intrinsic non-symbiotic and truncated haemoglobins and heterologous Vitreoscilla haemoglobin expression in plants

(2009) S. Jokipii-Lukkari et al.   JOURNAL OF EXPERIMENTAL BOTANY

Heme oxygenase-1 affords protection against noncerebral forms of severe malaria

(2009) E. Seixas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nitrite reductase activity of hemoglobin as a systemic nitric oxide generator mechanism to detoxify plasma hemoglobin produced during hemolysis

(2008) Peter C. Minneci et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

All hemoglobin-based oxygen carriers are not created equally

(2008) Paul W. Buehler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss

(2008) Roman Aranda et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS