Parenteral Ascorbate As a Cancer Therapeutic: A Reassessment Based on Pharmacokinetics
出版年份 2013 全文链接
标题
Parenteral Ascorbate As a Cancer Therapeutic: A Reassessment Based on Pharmacokinetics
作者
关键词
-
出版物
ANTIOXIDANTS & REDOX SIGNALING
Volume 19, Issue 17, Pages 2141-2156
出版商
Mary Ann Liebert Inc
发表日期
2013-04-29
DOI
10.1089/ars.2013.5372
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial
- (2013) J. L. Welsh et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Vitamin C in mouse and human red blood cells: An HPLC assay
- (2012) Hongyan Li et al. ANALYTICAL BIOCHEMISTRY
- Natural resistance to ascorbic acid induced oxidative stress is mainly mediated by catalase activity in human cancer cells and catalase-silencing sensitizes to oxidative stress
- (2012) Christoph Klingelhoeffer et al. BMC Complementary and Alternative Medicine
- Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment
- (2012) Lin Li et al. FREE RADICAL BIOLOGY AND MEDICINE
- Pharmacological concentrations of ascorbate radiosensitize glioblastoma multiforme primary cells by increasing oxidative DNA damage and inhibiting G2/M arrest
- (2012) Patries M. Herst et al. FREE RADICAL BIOLOGY AND MEDICINE
- Enhanced antitumor activity of vitamin C via p53 in Cancer cells
- (2012) Jinsun Kim et al. FREE RADICAL BIOLOGY AND MEDICINE
- Iron Overload in Human Disease
- (2012) Robert E. Fleming et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer
- (2012) Daniel A. Monti et al. PLoS One
- Pharmacological ascorbate induces cytotoxicity in prostate cancer cells through ATP depletion and induction of autophagy
- (2011) Ping Chen et al. ANTI-CANCER DRUGS
- Anti-cancer effect of pharmacologic ascorbate and its interaction with supplementary parenteral glutathione in preclinical cancer models
- (2011) Ping Chen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer
- (2011) Michael Graham Espey et al. FREE RADICAL BIOLOGY AND MEDICINE
- Ascorbic Acid Enhances Radiation-induced Apoptosis in an HL60 Human Leukemia Cell Line
- (2011) Koji SHINOZAKI et al. JOURNAL OF RADIATION RESEARCH
- Inhibitory Effect of Vitamin C in Combination With Vitamin K3 on Tumor Growth and Metastasis of Lewis Lung Carcinoma Xenografted in C57BL/6 Mice
- (2011) Ming-Feng Chen et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Pharmacologic Doses of Ascorbic Acid Repress Specificity Protein (Sp) Transcription Factors and Sp-Regulated Genes in Colon Cancer Cells
- (2011) Satya S. Pathi et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- In vitro screening of synergistic ascorbate–drug combinations for the treatment of malignant mesothelioma
- (2011) Simona Martinotti et al. TOXICOLOGY IN VITRO
- TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ9-tetrahydrocannabiorcol
- (2011) David A Andersson et al. Nature Communications
- Selective Ascorbate Toxicity in Malignant Mesothelioma
- (2010) Elia Ranzato et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- High dose of ascorbic acid induces cell death in mesothelioma cells
- (2010) Yukitoshi Takemura et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer
- (2010) M. F. Ullah et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs
- (2010) Anja Frömberg et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- H2O2-mediated Cytotoxicity of Pharmacologic Ascorbate Concentrations to Neuroblastoma Cells: Potential Role of Lactate and Ferritin
- (2010) Beate Deubzer et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer
- (2010) J. Du et al. CLINICAL CANCER RESEARCH
- Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice
- (2010) Christopher P. Corpe et al. JOURNAL OF CLINICAL INVESTIGATION
- Vitamin C: Intravenous Use by Complementary and Alternative Medicine Practitioners and Adverse Effects
- (2010) Sebastian J. Padayatty et al. PLoS One
- Pharmacologic concentrations of ascorbic acid cause diverse influence on differential expressions of angiogenic chemokine genes in different hepatocellular carcinoma cell lines
- (2009) Zu-Yau Lin et al. BIOMEDICINE & PHARMACOTHERAPY
- Comment re: Vitamin C Antagonizes the Cytotoxic Effects of Chemotherapy
- (2009) M. G. Espey et al. CANCER RESEARCH
- Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects
- (2009) Julien Verrax et al. FREE RADICAL BIOLOGY AND MEDICINE
- Proteomic analysis reveals upregulation of RKIP in S-180 implanted BALB/C mouse after treatment with ascorbic acid
- (2009) Seyeon Park et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis
- (2009) Chang-Hwan Yeom et al. Journal of Translational Medicine
- Ascorbic acid inhibits antitumor activity of bortezomib in vivo
- (2009) G Perrone et al. LEUKEMIA
- Antiproliferative Effect of Ascorbic Acid Is Associated with the Inhibition of Genes Necessary to Cell Cycle Progression
- (2009) Sophie Belin et al. PLoS One
- Phase I clinical trial of i.v. ascorbic acid in advanced malignancy
- (2008) L. J. Hoffer et al. ANNALS OF ONCOLOGY
- Vitamin C Antagonizes the Cytotoxic Effects of Antineoplastic Drugs
- (2008) M. L. Heaney et al. CANCER RESEARCH
- Vitamin C suppresses proliferation of the human melanoma cell SK-MEL-2 through the inhibition of cyclooxygenase-2 (COX-2) expression and the modulation of insulin-like growth factor II (IGF-II) production
- (2008) Seung Koo Lee et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Anti-angiogenic effect of high doses of ascorbic acid
- (2008) Nina A Mikirova et al. Journal of Translational Medicine
- Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
- (2008) Q. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now