The Role of Cysteine Oxidation in DJ-1 Function and Dysfunction

DJ-1: A novel independent prognostic marker for survival in glottic squamous cell carcinoma

(2010) Xiao-Lin Zhu et al.   CANCER SCIENCE

Keap1-Nrf2 activation in the presence and absence of DJ-1

(2010) Li Gan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Parkinson disease protein DJ-1 converts from a zymogen to a protease by carboxyl-terminal cleavage

(2010) Jue Chen et al.   HUMAN MOLECULAR GENETICS

DJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human  -syn toxicity

(2010) C. P. Ramsey et al.   HUMAN MOLECULAR GENETICS

Protein Aggregation in a Mutant Deficient in YajL, the Bacterial Homolog of the Parkinsonism-associated Protein DJ-1

(2010) Fatoum Kthiri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity

(2010) Sebastian Deeg et al.   JOURNAL OF CELL BIOLOGY

DJ-1, PINK1, and their effects on mitochondrial pathways

(2010) Mark R. Cookson   MOVEMENT DISORDERS

DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex

(2010) Joo-Young Im et al.   NEUROSCIENCE RESEARCH

Reduced Basal Autophagy and Impaired Mitochondrial Dynamics Due to Loss of Parkinson's Disease-Associated Protein DJ-1

(2010) Guido Krebiehl et al.   PLoS One

Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches

(2009) Candice E. Paulsen et al.   ACS Chemical Biology

Regulation of astrocyte inflammatory responses by the Parkinson’s disease-associated gene DJ-1

(2009) Jens Waak et al.   FASEB JOURNAL

Oxidizable Residues Mediating Protein Stability and Cytoprotective Interaction of DJ-1 with Apoptosis Signal-regulating Kinase 1

(2009) Jens Waak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1

(2009) Jeff Blackinton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease

(2009) Jeff Blackinton et al.   NEUROSCIENCE LETTERS

DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses

(2009) S. Vasseur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1

(2008) Deepti Malhotra et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Structure of the Stress Response Protein DR1199 fromDeinococcus radiodurans: A Member of the DJ-1 Superfamily

(2008) Emanuela Fioravanti et al.   BIOCHEMISTRY

Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1†,‡

(2008) Mahadevan Lakshminarasimhan et al.   BIOCHEMISTRY

Cysteine pKaDepression by a Protonated Glutamic Acid in Human DJ-1†‡

(2008) Anna C. Witt et al.   BIOCHEMISTRY

Proteomic analysis identifies MMP-9, DJ-1 and A1BG as overexpressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients

(2008) Mei Tian et al.   BMC CANCER

DJ-1 Could Predict Worse Prognosis in Esophageal Squamous Cell Carcinoma

(2008) H.-F. Yuen et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Aggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations

(2008) S Zucchelli et al.   CELL DEATH AND DIFFERENTIATION

Sumoylation is critical for DJ-1 to repress p53 transcriptional activity

(2008) Jun Fan et al.   FEBS LETTERS

Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1α: regulation by SUMOylation and oxidation

(2008) Nan Zhong et al.   HUMAN MOLECULAR GENETICS

DJ-1 Changes in G93A-SOD1 Transgenic Mice: Implications for Oxidative Stress in ALS

(2008) Nirit Lev et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson’s disease

(2008) Fang Liu et al.   JOURNAL OF NEUROCHEMISTRY

DJ-1-binding compounds prevent oxidative stress-induced cell death and movement defect in Parkinson’s disease model rats

(2008) Shin Miyazaki et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial localization of DJ-1 leads to enhanced neuroprotection

(2008) Eunsung Junn et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Proteomic Analysis of Oxidative Stress-Responsive Proteins in Human Pneumocytes: Insight into the Regulation of DJ-1 Expression

(2008) Xunbao Duan et al.   JOURNAL OF PROTEOME RESEARCH

DJ-1 knock-down in astrocytes impairs astrocyte-mediated neuroprotection against rotenone

(2008) Steven J. Mullett et al.   NEUROBIOLOGY OF DISEASE

Oxidative insults induce DJ-1 upregulation and redistribution: Implications for neuroprotection

(2008) Nirit Lev et al.   NEUROTOXICOLOGY

DJ-1 Modulates α-Synuclein Aggregation State in a Cellular Model of Oxidative Stress: Relevance for Parkinson's Disease and Involvement of HSP70

(2008) Sara Batelli et al.   PLoS One

RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways

(2008) M. P. van der Brug et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural effects of Parkinson's disease linked DJ-1 mutations

(2008) Gaetano Malgieri et al.   PROTEIN SCIENCE

Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes

(2008) Amanda K. Ashley et al.   TOXICOLOGY LETTERS

Expression and clinical role of DJ-1, a negative regulator of PTEN, in ovarian carcinoma

(2007) Ben Davidson et al.   HUMAN PATHOLOGY

Identification of prostate cancer antigens by automated high-throughput filter immunoscreening

(2007) Lene Alsøe et al.   JOURNAL OF IMMUNOLOGICAL METHODS