Biochemical Study of the Comparative Inhibition of Hepatitis C Virus RNA Polymerase by VX-222 and Filibuvir

Antiviral activity of the hepatitis C virus polymerase inhibitor filibuvir in genotype 1-infected patients

(2011) Frank Wagner et al.   HEPATOLOGY

Boceprevir for Previously Treated Chronic HCV Genotype 1 Infection

(2011) Bruce R. Bacon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection

(2011) Ira M. Jacobson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of De Novo-Initiated RNA Synthesis in Hepatitis C Virus RNA-Dependent RNA Polymerase by Intermolecular Interactions

(2010) S. Chinnaswamy et al.   JOURNAL OF VIROLOGY

Preclinical Characterization of PF-00868554, a Potent Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase

(2009) S. T. Shi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Recent advances in the development of NS5B polymerase inhibitors for the treatment of hepatitis C virus infection

(2009) Pierre L Beaulieu   EXPERT OPINION ON THERAPEUTIC PATENTS

Discovery of (R)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor

(2009) Hui Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

HCV796: A selective nonstructural protein 5B polymerase inhibitor with potent anti-hepatitis C virus activity In Vitro, in mice with chimeric human livers, and in humans infected with hepatitis C virus

(2008) Norman M. Kneteman et al.   HEPATOLOGY

A Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus Polymerase

(2008) Sreedhar Chinnaswamy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY