Genetic Analysis of Hypoxia Tolerance and Susceptibility in Drosophila and Humans

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

The yak genome and adaptation to life at high altitude

(2012) Qiang Qiu et al.   NATURE GENETICS

Hypoxia-Adaptation Involves Mitochondrial Metabolic Depression and Decreased ROS Leakage

(2012) Sameh S. Ali et al.   PLoS One

Ultrastructural Modifications in the Mitochondria of Hypoxia-Adapted Drosophila melanogaster

(2012) Guy Perkins et al.   PLoS One

Identification of Genes Underlying Hypoxia Tolerance in Drosophila by a P-element Screen

(2012) Priti Azad et al.   G3-Genes Genomes Genetics

Genetic adaptation to high altitude in the Ethiopian highlands

(2012) Laura B Scheinfeldt et al.   GENOME BIOLOGY

Effects of Oxygen on Growth and Size: Synthesis of Molecular, Organismal, and Evolutionary Studies with Drosophila melanogaster

(2011) Jon F. Harrison et al.   Annual Review of Physiology

High altitude adaptation in Daghestani populations from the Caucasus

(2011) Luca Pagani et al.   HUMAN GENETICS

Molecular Evolution of the Metazoan PHD–HIF Oxygen-Sensing System

(2011) Kalle T. Rytkönen et al.   MOLECULAR BIOLOGY AND EVOLUTION

Oxygen Sensing, Homeostasis, and Disease

(2011) Gregg L. Semenza   NEW ENGLAND JOURNAL OF MEDICINE

Experimental selection of hypoxia-tolerant Drosophila melanogaster

(2011) D. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Variations in Tibetan Populations and High-Altitude Adaptation at the Himalayas

(2010) Y. Peng et al.   MOLECULAR BIOLOGY AND EVOLUTION

Natural selection on EPAS1 (HIF2 ) associated with low hemoglobin concentration in Tibetan highlanders

(2010) C. M. Beall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiological Adaptation of the Cardiovascular System to High Altitude

(2010) Robert Naeije   PROGRESS IN CARDIOVASCULAR DISEASES

Genetic Evidence for High-Altitude Adaptation in Tibet

(2010) T. S. Simonson et al.   SCIENCE

Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude

(2010) X. Yi et al.   SCIENCE

Drosophila Genome-Wide RNAi Screen Identifies Multiple Regulators of HIF–Dependent Transcription in Hypoxia

(2010) Andrés Dekanty et al.   PLoS Genetics

Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data

(2010) Abigail Bigham et al.   PLoS Genetics

Distinct Mechanisms Underlying Tolerance to Intermittent and Constant Hypoxia in Drosophila melanogaster

(2009) Priti Azad et al.   PLoS One

An RNA Interference Screen Identifies a Novel Regulator of Target of Rapamycin That Mediates Hypoxia Suppression of Translation in Drosophila S2 Cells

(2008) Soo-Jung Lee et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanisms Underlying Hypoxia Tolerance in Drosophila melanogaster: hairy as a Metabolic Switch

(2008) Dan Zhou et al.   PLoS Genetics

Gene expression in mouse brain following chronic hypoxia: role of sarcospan in glial cell death

(2007) Dan Zhou et al.   PHYSIOLOGICAL GENOMICS