Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

(2012) Christian Beyer et al.   ANNALS OF THE RHEUMATIC DISEASES

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

(2012) Jun Wei et al.   ARTHRITIS AND RHEUMATISM

Small Molecule Antagonists of the Wnt/Beta-Catenin Signaling Pathway Target Breast Tumor-Initiating Cells in a Her2/Neu Mouse Model of Breast Cancer

(2012) Robin M. Hallett et al.   PLoS One

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

Morphogen Pathways in Systemic Sclerosis

(2012) Christian Beyer et al.   Current Rheumatology Reports

Inhibition of glycogen synthase kinase 3  induces dermal fibrosis by activation of the canonical Wnt pathway

(2011) C. Bergmann et al.   ANNALS OF THE RHEUMATIC DISEASES

Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: A novel mouse model for scleroderma?

(2011) Jun Wei et al.   ARTHRITIS AND RHEUMATISM

Platelet-derived serotonin links vascular disease and tissue fibrosis

(2011) Clara Dees et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeted Inhibition of  -Catenin/CBP Signaling Ameliorates Renal Interstitial Fibrosis

(2011) S. Hao et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Animal models of systemic sclerosis: Prospects and limitations

(2010) Christian Beyer et al.   ARTHRITIS AND RHEUMATISM

New avenues to target Wnt/β-catenin signaling

(2010) Folkert Verkaar et al.   DRUG DISCOVERY TODAY

Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis

(2010) W. R. Henderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY