Role of PGC-1α signaling in skeletal muscle health and disease

PGC-1α: a master gene that is hard to master

(2012) Dan Lindholm et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Rescue of Dystrophic Skeletal Muscle by PGC-1α Involves a Fast to Slow Fiber Type Shift in the mdx Mouse

(2012) Joshua T. Selsby et al.   PLoS One

The p65 subunit of NF-κB binds to PGC-1α, linking inflammation and metabolic disturbances in cardiac cells

(2010) David Álvarez-Guardia et al.   CARDIOVASCULAR RESEARCH

Role of nuclear factor κB in cardiovascular health and disease

(2010) Kim van der Heiden et al.   CLINICAL SCIENCE

PGC-1α is required for training-induced prevention of age-associated decline in mitochondrial enzymes in mouse skeletal muscle

(2010) Lotte Leick et al.   EXPERIMENTAL GERONTOLOGY

PGC-1α and Myokines in the Aging Muscle – A Mini-Review

(2010) Anne-Sophie Arnold et al.   GERONTOLOGY

Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor γ coactivator 1α

(2010) Christoph Handschin   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

(2010) Xingxing Kong et al.   PLoS One

PGC-1α plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle

(2009) Tuoyu Geng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Peroxisome proliferator-activated receptor-γ coactivator-1α in muscle links metabolism to inflammation

(2009) Christoph Handschin   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Exercise activation of muscle peroxisome proliferator-activated receptor-γ coactivator-1α signaling is redox sensitive

(2009) Chounghun Kang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanical ventilation induces diaphragmatic mitochondrial dysfunction and increased oxidant production

(2009) Andreas N. Kavazis et al.   FREE RADICAL BIOLOGY AND MEDICINE

PGC-1α and PGC-1β Regulate Mitochondrial Density in Neurons

(2009) Przemyslaw Wareski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exercise Training Attenuates Aging-associated Reduction In Mitochondrial Biogenesis In Rat Skeletal Muscle

(2009) Choung-Hun Kang et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of exercise and PGC1α in inflammation and chronic disease

(2008) Christoph Handschin et al.   NATURE

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

Modulation of skeletal muscle antioxidant defense by exercise: Role of redox signaling

(2007) Li Li Ji   FREE RADICAL BIOLOGY AND MEDICINE