Checkpoints of B cell differentiation: visualizing Ig-centric processes

STAT3-Mediated Up-Regulation of BLIMP1 Is Coordinated with BCL6 Down-Regulation to Control Human Plasma Cell Differentiation

(2014) S. A. Diehl et al.   JOURNAL OF IMMUNOLOGY

The establishment of early B cell tolerance in humans: lessons from primary immunodeficiency diseases

(2012) Eric Meffre   Annals of the New York Academy of Sciences

Regulation of mucosal IgA responses: lessons from primary immunodeficiencies

(2011) Andrea Cerutti et al.   Annals of the New York Academy of Sciences

IL-7R expression and IL-7 signaling confer a distinct phenotype on developing human B-lineage cells

(2011) S. E. Nodland et al.   BLOOD

B-cell replication history and somatic hypermutation status identify distinct pathophysiologic backgrounds in common variable immunodeficiency

(2011) G. J. Driessen et al.   BLOOD

Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

(2011) M. A. Berkowska et al.   BLOOD

The Distal VH Gene Cluster of the Igh Locus Contains Distinct Regulatory Elements with Pax5 Transcription Factor-Dependent Activity in Pro-B Cells

(2011) Anja Ebert et al.   IMMUNITY

Sustained antibody responses depend on CD28 function in bone marrow–resident plasma cells

(2011) Cheryl H. Rozanski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells

(2011) S. C. Degner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment

(2011) F. Notta et al.   SCIENCE

Loss of juxtaposition of RAG-induced immunoglobulin DNA ends is implicated in the precursor B-cell differentiation defect in NBS patients

(2010) M. van der Burg et al.   BLOOD

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

(2010) Y.-C. Wu et al.   BLOOD

Human peripheral blood B-cell compartments: A crossroad in B-cell traffic

(2010) M. Perez-Andres et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Circulating human B and plasma cells. Age-associated changes in counts and detailed characterization of circulating normal CD138- and CD138+ plasma cells

(2010) A. Caraux et al.   HAEMATOLOGICA

Load and lock: the molecular mechanisms of B-lymphocyte commitment

(2010) Sasan Zandi et al.   IMMUNOLOGICAL REVIEWS

The Mouse Immunoglobulin Heavy Chain V-D Intergenic Sequence Contains Insulators That May Regulate Ordered V(D)J Recombination

(2010) Karen Featherstone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency

(2010) Menno C. van Zelm et al.   JOURNAL OF CLINICAL INVESTIGATION

B cell–intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

(2010) Danielle T. Avery et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

(2010) Bing He et al.   NATURE IMMUNOLOGY

The Density of CD10 Corresponds to Commitment and Progression in the Human B Lymphoid Lineage

(2010) Michiko Ichii et al.   PLoS One

Ordering human CD34+CD10-CD19+ pre/pro-B-cell and CD19- common lymphoid progenitor stages in two pro-B-cell development pathways

(2010) E. Sanz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Primary B Cell Immunodeficiencies: Comparisons and Contrasts

(2009) Mary Ellen Conley et al.   Annual Review of Immunology

Human Marginal Zone B Cells

(2009) Jean-Claude Weill et al.   Annual Review of Immunology

Impaired B-cell development at the pre-BII-cell stage in galectin-1-deficient mice due to inefficient pre-BII/stromal cell interactions

(2009) M. Espeli et al.   BLOOD

Chromatin Architecture and the Generation of Antigen Receptor Diversity

(2009) Suchit Jhunjhunwala et al.   CELL

PI3 Kinase Signals BCR-Dependent Mature B Cell Survival

(2009) Lakshmi Srinivasan et al.   CELL

MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

(2009) Beth A. Helmink et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci

(2009) Kristina Beck et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

(2009) Stephen Malin et al.   NATURE IMMUNOLOGY

B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans

(2009) K. Warnatz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights into the regulation of human B-cell differentiation

(2009) Heike Schmidlin et al.   TRENDS IN IMMUNOLOGY

Blood-borne human plasma cells in steady state are derived from mucosal immune responses

(2008) H. E. Mei et al.   BLOOD

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells

(2008) R. Mansson et al.   BLOOD

The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions

(2008) Suchit Jhunjhunwala et al.   CELL

Perivascular clusters of dendritic cells provide critical survival signals to B cells in bone marrow niches

(2008) Anita Sapoznikov et al.   NATURE IMMUNOLOGY

Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease

(2008) Maria Florencia Delgado et al.   NATURE MEDICINE