A comprehensive analysis of SNCA -related genetic risk in sporadic parkinson disease

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

(2018) Rita Guerreiro et al.   LANCET NEUROLOGY

Genetic risk factors for cognitive decline in Parkinson's disease: a review of the literature

(2017) E. S. Fagan et al.   EUROPEAN JOURNAL OF NEUROLOGY

Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci

(2017) John F Fullard et al.   HUMAN MOLECULAR GENETICS

Targeting α-Synuclein as a therapy for Parkinson's disease: The battle begins

(2017) C. Warren Olanow et al.   MOVEMENT DISORDERS

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

(2017) Diana Chang et al.   NATURE GENETICS

Fast, scalable prediction of deleterious noncoding variants from functional and population genomic data

(2017) Yi-Fei Huang et al.   NATURE GENETICS

β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s disease

(2017) Shuchi Mittal et al.   SCIENCE

Interpreting Gene Expression Effects of Disease-Associated Variants: A Lesson from SNCA rs356168

(2017) Omolara-Chinue Glenn et al.   Frontiers in Genetics

A cumulative genetic risk score predicts progression in Parkinson's disease

(2016) Lasse Pihlstrøm et al.   MOVEMENT DISORDERS

Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression

(2016) Frank Soldner et al.   NATURE

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Genome-wide assessment of Parkinson's disease in a Southern Spanish population

(2016) Sara Bandrés-Ciga et al.   NEUROBIOLOGY OF AGING

Comprehensive promoter level expression quantitative trait loci analysis of the human frontal lobe

(2016) Cornelis Blauwendraat et al.   Genome Medicine

Polygenic risk of Parkinson disease is correlated with disease age at onset

(2015) Valentina Escott-Price et al.   ANNALS OF NEUROLOGY

The Prion Hypothesis of Parkinson’s Disease

(2015) Yaping Chu et al.   Current Neurology and Neuroscience Reports

Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI)

(2015) Mike A. Nalls et al.   MOVEMENT DISORDERS

The NINDS Parkinson's disease biomarkers program

(2015) Liana S. Rosenthal et al.   MOVEMENT DISORDERS

Structure of the toxic core of α-synuclein from invisible crystals

(2015) Jose A. Rodriguez et al.   NATURE

NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases

(2015) Mike A. Nalls et al.   NEUROBIOLOGY OF AGING

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

A promoter-level mammalian expression atlas

(2014)   NATURE

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

(2014) Mike A Nalls et al.   NATURE GENETICS

Genetic variability in the regulation of gene expression in ten regions of the human brain

(2014) Adaikalavan Ramasamy et al.   NATURE NEUROSCIENCE

Large-Scale Identification of Coregulated Enhancer Networks in the Adult Human Brain

(2014) Marit W. Vermunt et al.   Cell Reports

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

(2012) Oliver Stegle et al.   Nature Protocols

Supportive evidence for 11 loci from genome-wide association studies in Parkinson's disease

(2012) Lasse Pihlstrøm et al.   NEUROBIOLOGY OF AGING

Genome Wide Assessment of Young Onset Parkinson’s Disease from Finland

(2012) Dena G. Hernandez et al.   PLoS One

Alternative α-synuclein transcript usage as a convergent mechanism in Parkinson's disease pathology

(2012) Herve Rhinn et al.   Nature Communications

Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2

(2011) Nathan Pankratz et al.   ANNALS OF NEUROLOGY

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

(2011) Brit Mollenhauer et al.   LANCET NEUROLOGY

Web-Based Genome-Wide Association Study Identifies Two Novel Loci and a Substantial Genetic Component for Parkinson's Disease

(2011) Chuong B. Do et al.   PLoS Genetics

A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease

(2011) et al.   PLoS Genetics

Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21

(2010) et al.   HUMAN MOLECULAR GENETICS

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

(2010) Taye H Hamza et al.   NATURE GENETICS

The effect of SNCA 3′ region on the levels of SNCA-112 splicing variant

(2010) Jeanette J. McCarthy et al.   NEUROGENETICS

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

(2009) Wataru Satake et al.   NATURE GENETICS

Genome-wide association study reveals genetic risk underlying Parkinson's disease

(2009) Javier Simón-Sánchez et al.   NATURE GENETICS

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

(2009) E. Sidransky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomewide association study for susceptibility genes contributing to familial Parkinson disease

(2008) Nathan Pankratz et al.   HUMAN GENETICS