Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
出版年份 2016 全文链接
标题
Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
作者
关键词
-
出版物
NATURE
Volume 533, Issue 7601, Pages 95-99
出版商
Springer Nature
发表日期
2016-04-20
DOI
10.1038/nature17939
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Integrative analysis of haplotype-resolved epigenomes across human tissues
- (2015) Danny Leung et al. NATURE
- minimac2: faster genotype imputation
- (2014) Christian Fuchsberger et al. BIOINFORMATICS
- Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
- (2014) Mike A Nalls et al. NATURE GENETICS
- Large-Scale Identification of Coregulated Enhancer Networks in the Adult Human Brain
- (2014) Marit W. Vermunt et al. Cell Reports
- One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
- (2013) Haoyi Wang et al. CELL
- Super-Enhancers in the Control of Cell Identity and Disease
- (2013) Denes Hnisz et al. CELL
- Mapping Human Epigenomes
- (2013) Chloe M. Rivera et al. CELL
- Single-Cell Analysis Reveals that Expression of Nanog Is Biallelic and Equally Variable as that of Other Pluripotency Factors in Mouse ESCs
- (2013) Dina A. Faddah et al. Cell Stem Cell
- The genetics of Parkinson's disease: Progress and therapeutic implications
- (2013) Andrew B. Singleton et al. MOVEMENT DISORDERS
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Neuropathologic substrates of Parkinson disease dementia
- (2012) David J. Irwin et al. ANNALS OF NEUROLOGY
- Increased Expression of Alpha-Synuclein by SNCA Duplication is Associated with Resistance to Toxic Stimuli
- (2012) Han-Joon Kim et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Neuronal vulnerability, pathogenesis, and Parkinson's disease
- (2012) David Sulzer et al. MOVEMENT DISORDERS
- DNase I sensitivity QTLs are a major determinant of human expression variation
- (2012) Jacob F. Degner et al. NATURE
- An anatomically comprehensive atlas of the adult human brain transcriptome
- (2012) Michael J. Hawrylycz et al. NATURE
- Interpreting noncoding genetic variation in complex traits and human disease
- (2012) Lucas D Ward et al. NATURE BIOTECHNOLOGY
- Chromatin marks identify critical cell types for fine mapping complex trait variants
- (2012) Gosia Trynka et al. NATURE GENETICS
- Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
- (2012) Bryan Howie et al. NATURE GENETICS
- Emx2 is a dose-dependent negative regulator of Sox2 telencephalic enhancers
- (2012) J. Mariani et al. NUCLEIC ACIDS RESEARCH
- iPSC Disease Modeling
- (2012) F. Soldner et al. SCIENCE
- Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
- (2012) M. T. Maurano et al. SCIENCE
- Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database
- (2012) Christina M. Lill et al. PLoS Genetics
- Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2
- (2011) Nathan Pankratz et al. ANNALS OF NEUROLOGY
- Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
- (2011) Frank Soldner et al. CELL
- Cyclin-G-associated kinase modifies -synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study
- (2011) A. Dumitriu et al. HUMAN MOLECULAR GENETICS
- Parkinson's disease and α-synuclein expression
- (2011) Michael J. Devine et al. MOVEMENT DISORDERS
- Mapping and analysis of chromatin state dynamics in nine human cell types
- (2011) Jason Ernst et al. NATURE
- Direct reprogramming of mouse fibroblasts to neural progenitors
- (2011) J. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- METAL: fast and efficient meta-analysis of genomewide association scans
- (2010) C. J. Willer et al. BIOINFORMATICS
- Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations
- (2010) Christopher J. Lengner et al. CELL
- Genetic Heterogeneity in Human Disease
- (2010) Jon McClellan et al. CELL
- Nkx6 Transcription Factors and Ptf1a Function as Antagonistic Lineage Determinants in Multipotent Pancreatic Progenitors
- (2010) Ashleigh E. Schaffer et al. DEVELOPMENTAL CELL
- Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome
- (2010) R. C. DeKelver et al. GENOME RESEARCH
- Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease
- (2010) Isidre Ferrer et al. JOURNAL OF NEURAL TRANSMISSION
- Variability in gene expression underlies incomplete penetrance
- (2010) Arjun Raj et al. NATURE
- A unique chromatin signature uncovers early developmental enhancers in humans
- (2010) Alvaro Rada-Iglesias et al. NATURE
- Histone H3K27ac separates active from poised enhancers and predicts developmental state
- (2010) M. P. Creyghton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
- (2009) Frank Soldner et al. CELL
- Expansion of the Parkinson disease-associated SNCA- Rep1 allele upregulates human α-synuclein in transgenic mouse brain
- (2009) Kenneth D. Cronin et al. HUMAN MOLECULAR GENETICS
- Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
- (2009) Dirk Hockemeyer et al. NATURE BIOTECHNOLOGY
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
- (2009) Ben Langmead et al. GENOME BIOLOGY
- Sequential Expression of Pluripotency Markers during Direct Reprogramming of Mouse Somatic Cells
- (2008) Tobias Brambrink et al. Cell Stem Cell
- Imaging individual mRNA molecules using multiple singly labeled probes
- (2008) Arjun Raj et al. NATURE METHODS
- Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
- (2008) Da Wei Huang et al. NUCLEIC ACIDS RESEARCH
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
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