Differential Effects of β3 - versus β2 -Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3-Derived α/β-Peptides
出版年份 2018 全文链接
标题
Differential Effects of β3
- versus β2
-Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3-Derived α/β-Peptides
作者
关键词
-
出版物
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2018-08-31
DOI
10.1002/anie.201806909
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Thermodynamic Scale of β-Amino Acid Residue Propensities for an α-Helix-like Conformation
- (2018) Brian F. Fisher et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Right-Handed Helical Foldamers Consisting of De Novo d-AApeptides
- (2017) Peng Teng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors
- (2017) Avi Ashkenazi et al. NATURE REVIEWS DRUG DISCOVERY
- An α-Helix-Mimicking 12,13-Helix: Designed α/β/γ-Foldamers as Selective Inhibitors of Protein-Protein Interactions
- (2016) Claire M. Grison et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Comparison of design strategies for α-helix backbone modification in a protein tertiary fold
- (2016) Nathan A. Tavenor et al. CHEMICAL COMMUNICATIONS
- Therapeutic Potential of Foldamers: From Chemical Biology Tools To Drug Candidates?
- (2016) Ranganath Gopalakrishnan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Small molecules, big targets: drug discovery faces the protein–protein interaction challenge
- (2016) Duncan E. Scott et al. NATURE REVIEWS DRUG DISCOVERY
- Systematic Targeting of Protein–Protein Interactions
- (2016) Ashley E. Modell et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics
- (2015) Kimberly J. Peterson-Kaufman et al. ACS Chemical Biology
- Hydrocarbon Stapled Peptides as Modulators of Biological Function
- (2015) Philipp M. Cromm et al. ACS Chemical Biology
- α-Peptide-Oligourea Chimeras: Stabilization of Short α-Helices by Non-Peptide Helical Foldamers
- (2015) Juliette Fremaux et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes
- (2015) Marta Pelay-Gimeno et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Interaction of β3/β2-Peptides, Consisting of Val-Ala-Leu Segments, with POPC Giant Unilamellar Vesicles (GUVs) and White Blood Cancer Cells (U937) - A New Type of Cell-Penetrating Peptides, and a Surprising Chain-Length Dependence of Their Vesicle- and Ce
- (2015) Beata Kolesinska et al. CHEMISTRY & BIODIVERSITY
- Synthesis and screening of small-molecule α-helix mimetic libraries targeting protein–protein interactions
- (2015) Heejo Moon et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- α/β-Peptide Foldamers Targeting Intracellular Protein–Protein Interactions with Activity in Living Cells
- (2015) James W. Checco et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Stereocontrolled protein surface recognition using chiral oligoamide proteomimetic foldamers
- (2015) Valeria Azzarito et al. Chemical Science
- Structure of Class B GPCRs: new horizons for drug discovery
- (2014) Andrea Bortolato et al. BRITISH JOURNAL OF PHARMACOLOGY
- Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality
- (2014) Michelle R. Arkin et al. CHEMISTRY & BIOLOGY
- α-Helix mimetics: Outwards and upwards
- (2013) Madura K.P. Jayatunga et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Structure-Guided Rational Design of α/β-Peptide Foldamers with High Affinity for BCL-2 Family Prosurvival Proteins
- (2013) Brian J. Smith et al. CHEMBIOCHEM
- Pharmacokinetics and Pharmacokinetic–Pharmacodynamic Correlations of Therapeutic Peptides
- (2013) Lei Diao et al. CLINICAL PHARMACOKINETICS
- Inhibition of α-helix-mediated protein–protein interactions using designed molecules
- (2013) Valeria Azzarito et al. Nature Chemistry
- ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
- (2013) Andrew J Souers et al. NATURE MEDICINE
- Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
- (2013) Peter E. Czabotar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structural Basis of Bcl-xL Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design
- (2011) Erinna F. Lee et al. CHEMBIOCHEM
- Synthetic foldamers
- (2011) Gilles Guichard et al. CHEMICAL COMMUNICATIONS
- Assessing Helical Protein Interfaces for Inhibitor Design
- (2011) Brooke N. Bullock et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Evaluation of Diverse α/β-Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain
- (2011) Melissa D. Boersma et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structural Mimicry of the α-Helix in Aqueous Solution with an Isoatomic α/β/γ-Peptide Backbone
- (2011) Tomohisa Sawada et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The BH3 α-Helical Mimic BH3-M6 Disrupts Bcl-XL, Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent Manner
- (2010) Aslamuzzaman Kazi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-alkylated oligoamide α-helical proteomimetics
- (2010) Frederick Campbell et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Oligooxopiperazines as Nonpeptidic α-Helix Mimetics
- (2010) Petra Tošovská et al. ORGANIC LETTERS
- High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xL
- (2009) Erinna F. Lee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structural and biological mimicry of protein surface recognition by / -peptide foldamers
- (2009) W. S. Horne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Hydrogen Bond Surrogate Approach for Stabilization of Short Peptide Sequences in α-Helical Conformation
- (2008) Anupam Patgiri et al. ACCOUNTS OF CHEMICAL RESEARCH
- New Open-Chain and Cyclic Tetrapeptides, Consisting ofα-,β2-, andβ3-Amino-Acid Residues, as Somatostatin Mimics - A Survey
- (2008) Dieter Seebach et al. HELVETICA CHIMICA ACTA
- A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation
- (2008) Erinna F. Lee et al. JOURNAL OF CELL BIOLOGY
- Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: Application to the Bim BH3 domain
- (2008) Melissa D. Boersma et al. PROTEIN SCIENCE
- Enantioselective Preparation of β²-Amino Acid Derivatives for β-Peptide Synthesis
- (2008) Dieter Seebach et al. SYNTHESIS-STUTTGART
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