Chiral Amine Synthesis Using ω-Transaminases: An Amine Donor that Displaces Equilibria and Enables High-Throughput Screening

Phenylalanine Ammonia Lyase Catalyzed Synthesis of Amino Acids by an MIO-Cofactor Independent Pathway

(2014) Sarah L. Lovelock et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Regio- and Stereoselective ω-Transaminase/Monoamine Oxidase Cascade for the Synthesis of Chiral 2,5-Disubstituted Pyrrolidines

(2014) Elaine O'Reilly et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Monoamine Oxidase-ω-Transaminase Cascade for the Deracemisation and Dealkylation of Amines

(2014) Elaine O'Reilly et al.   ChemCatChem

High throughput screening methods for ω-transaminases

(2013) Sam Mathew et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Asymmetric Reduction of Cyclic Imines Catalyzed by a Whole-Cell Biocatalyst Containing an (S)-Imine Reductase

(2013) Friedemann Leipold et al.   ChemCatChem

Priming ammonia lyases and aminomutases for industrial and therapeutic applications

(2013) Matthew M Heberling et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Engineering an Enantioselective Amine Oxidase for the Synthesis of Pharmaceutical Building Blocks and Alkaloid Natural Products

(2013) Diego Ghislieri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Monoamine Oxidase (MAO-N) Catalyzed Deracemization of Tetrahydro-β-carbolines: Substrate Dependent Switch in Enantioselectivity

(2013) Diego Ghislieri et al.   ACS Catalysis

Development of an Amine Dehydrogenase for Synthesis of Chiral Amines

(2012) Michael J. Abrahamson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase

(2012) Bo Wang et al.   CHEMICAL COMMUNICATIONS

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Efficient, Chemoenzymatic Process for Manufacture of the Boceprevir Bicyclic [3.1.0]Proline Intermediate Based on Amine Oxidase-Catalyzed Desymmetrization

(2012) Tao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

ω-Transaminases for the Production of Optically Pure Amines and Unnatural Amino Acids

(2012) Sam Mathew et al.   ACS Catalysis

Asymmetric Synthesis of (S)-2-Indolinecarboxylic Acid by Combining Biocatalysis and Homogeneous Catalysis

(2011) Ben de Lange et al.   ChemCatChem

Practical chiral alcohol manufacture using ketoreductases

(2010) Gjalt W Huisman et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Privileged scaffolds for library design and drug discovery

(2010) Matthew E Welsch et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

ω-Transaminases for the synthesis of non-racemic α-chiral primary amines

(2010) Dominik Koszelewski et al.   TRENDS IN BIOTECHNOLOGY

Biocatalytic Routes to Optically Active Amines

(2009) Matthias Höhne et al.   ChemCatChem

Directed evolution drives the next generation of biocatalysts

(2009) Nicholas J Turner   Nature Chemical Biology

Formal Asymmetric Biocatalytic Reductive Amination

(2008) Dominik Koszelewski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directed Evolution of Galactose Oxidase: Generation of Enantioselective Secondary Alcohol Oxidases

(2008) Franck Escalettes et al.   CHEMBIOCHEM

Rapid screening and scale-up of transaminase catalysed reactions

(2008) Matthew D. Truppo et al.   ORGANIC & BIOMOLECULAR CHEMISTRY