A Regio- and Stereoselective ω-Transaminase/Monoamine Oxidase Cascade for the Synthesis of Chiral 2,5-Disubstituted Pyrrolidines

Biocatalysis in Organic Chemistry and Biotechnology: Past, Present, and Future

(2013) Manfred T. Reetz   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering an Enantioselective Amine Oxidase for the Synthesis of Pharmaceutical Building Blocks and Alkaloid Natural Products

(2013) Diego Ghislieri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocatalytic retrosynthesis

(2013) Nicholas J Turner et al.   Nature Chemical Biology

Use of ω-Transaminase Enzyme Chemistry in the Synthesis of a JAK2 Kinase Inhibitor

(2013) Lianne Frodsham et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Monoamine Oxidase (MAO-N) Catalyzed Deracemization of Tetrahydro-β-carbolines: Substrate Dependent Switch in Enantioselectivity

(2013) Diego Ghislieri et al.   ACS Catalysis

Redox Self-Sufficient Biocatalyst Network for the Amination of Primary Alcohols

(2012) Johann H. Sattler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regio- and Stereoselective Monoamination of Diketones without Protecting Groups

(2012) Robert C. Simon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directed Evolution of the Enzyme Monoamine Oxidase (MAO-N): Highly Efficient Chemo-enzymatic Deracemisation of the Alkaloid (±)-Crispine A

(2012) Ian Rowles et al.   ChemCatChem

Draft Genome Sequence of the Anaerobic, Nitrate-Dependent, Fe(II)-Oxidizing Bacterium Pseudogulbenkiania ferrooxidans Strain 2002

(2012) K. G. Byrne-Bailey et al.   JOURNAL OF BACTERIOLOGY

Efficient, Chemoenzymatic Process for Manufacture of the Boceprevir Bicyclic [3.1.0]Proline Intermediate Based on Amine Oxidase-Catalyzed Desymmetrization

(2012) Tao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

ω-Transaminases for the Production of Optically Pure Amines and Unnatural Amino Acids

(2012) Sam Mathew et al.   ACS Catalysis

Multi-Enzymatic Cascade Reactions: Overview and Perspectives

(2011) Emanuele Ricca et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Synthesis of (S)-2-Indolinecarboxylic Acid by Combining Biocatalysis and Homogeneous Catalysis

(2011) Ben de Lange et al.   ChemCatChem

A highly efficient synthesis of telaprevir by strategic use of biocatalysis and multicomponent reactions

(2010) Anass Znabet et al.   CHEMICAL COMMUNICATIONS

Recent biocatalytic oxidation–reduction cascades

(2010) Joerg H Schrittwieser et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Pd-Catalyzed Carboamination of Oxazolidin-2-ones: A Stereoselective Route totrans-2,5-Disubstituted Pyrrolidines

(2010) Georgia S. Lemen et al.   ORGANIC LETTERS

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

(2010) C. K. Savile et al.   SCIENCE

ω-Transaminases for the synthesis of non-racemic α-chiral primary amines

(2010) Dominik Koszelewski et al.   TRENDS IN BIOTECHNOLOGY

Biocatalytic Routes to Optically Active Amines

(2009) Matthias Höhne et al.   ChemCatChem

Sequential Mannich-Aza-Michael Reactions for the Stereodivergent Synthesis of Highly Substituted Pyrrolidines

(2009) Charlotte Enkisch et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Directed evolution drives the next generation of biocatalysts

(2009) Nicholas J Turner   Nature Chemical Biology

Asymmetric Synthesis ofcis- andtrans-2,5-Disubstituted Pyrrolidines from 3-Oxo Pyrrolidine 2-Phosphonates:  Synthesis of (+)-Preussin and Analogs

(2008) Franklin A. Davis et al.   ORGANIC LETTERS