标题
Deorphaning Pyrrolopyrazines as Potent Multi-Target Antimalarial Agents
作者
关键词
-
出版物
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 53, Issue 27, Pages 7079-7084
出版商
Wiley
发表日期
2014-06-04
DOI
10.1002/anie.201311162
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Identifying the macromolecular targets of de novo-designed chemical entities through self-organizing map consensus
- (2014) D. Reker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chemically Advanced Template Search (CATS) for Scaffold-Hopping and Prospective Target Prediction for ‘Orphan’ Molecules
- (2013) Michael Reutlinger et al. Molecular Informatics
- Targeting Plasmodium PI(4)K to eliminate malaria
- (2013) Case W. McNamara et al. NATURE
- Common non-epigenetic drugs as epigenetic modulators
- (2013) Jörn Lötsch et al. TRENDS IN MOLECULAR MEDICINE
- New antibiotics for bad bugs: where are we?
- (2013) Matteo Bassetti et al. Annals of Clinical Microbiology and Antimicrobials
- Prediction of the P. falciparum Target Space Relevant to Malaria Drug Discovery
- (2013) Andreas Spitzmüller et al. PLoS Computational Biology
- Global malaria mortality between 1980 and 2010: a systematic analysis
- (2012) Christopher JL Murray et al. LANCET
- Mapping the genome of Plasmodium falciparum on the drug-like chemical space reveals novel anti-malarial targets and potential drug leads
- (2012) Kasper Jensen et al. Molecular BioSystems
- Finding the sweet spot: the role of nature and nurture in medicinal chemistry
- (2012) Michael M. Hann et al. NATURE REVIEWS DRUG DISCOVERY
- Agrochemicals against Malaria, Sleeping Sickness, Leishmaniasis and Chagas Disease
- (2012) Matthias Witschel et al. PLoS Neglected Tropical Diseases
- Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum
- (2011) Lev Solyakov et al. Nature Communications
- Architectural Repertoire of Ligand-Binding Pockets on Protein Surfaces
- (2010) Martin Weisel et al. CHEMBIOCHEM
- Self-organizing molecular fingerprints: a ligand-based view on drug-like chemical space and off-target prediction
- (2010) Gisbert Schneider et al. Future Medicinal Chemistry
- When is Chemical Similarity Significant? The Statistical Distribution of Chemical Similarity Scores and Its Extreme Values
- (2010) Pierre Baldi et al. Journal of Chemical Information and Modeling
- Self-Organizing Fuzzy Graphs for Structure-Based Comparison of Protein Pockets
- (2010) Felix Reisen et al. JOURNAL OF PROTEOME RESEARCH
- Target Profile Prediction: Cross-Activation of Peroxisome Proliferator-Activated Receptor (PPAR) and Farnesoid X Receptor (FXR)
- (2010) Ramona Steri et al. Molecular Informatics
- Thousands of chemical starting points for antimalarial lead identification
- (2010) Francisco-Javier Gamo et al. NATURE
- The influence of lead discovery strategies on the properties of drug candidates
- (2009) György M. Keserü et al. NATURE REVIEWS DRUG DISCOVERY
- Self-Organizing Maps in Drug Discovery: Compound Library Design, Scaffold-Hopping, Repurposing
- (2008) P. Schneider et al. CURRENT MEDICINAL CHEMISTRY
- In silicoactivity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen
- (2008) David Plouffe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protein kinases of malaria parasites: an update
- (2008) Christian Doerig et al. TRENDS IN PARASITOLOGY
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