Mild and Rapid Pd-Catalyzed Cross-Coupling with Hydrazine in Continuous Flow: Application to the Synthesis of Functionalized Heterocycles

Flow Chemistry - A Key Enabling Technology for (Multistep) Organic Synthesis

(2012) Jens Wegner et al.   ADVANCED SYNTHESIS & CATALYSIS

In Situ Generated Iron Oxide Nanocrystals as Efficient and Selective Catalysts for the Reduction of Nitroarenes using a Continuous Flow Method

(2012) David Cantillo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of nickel nanoparticles by hydrazine reduction: mechanistic study and continuous flow synthesis

(2012) Ravi Eluri et al.   JOURNAL OF NANOPARTICLE RESEARCH

Assembly of N,N-Disubstituted Hydrazines and 1-Aryl-1H-indazoles via Copper-Catalyzed Coupling Reactions

(2012) Xiaodong Xiong et al.   ORGANIC LETTERS

Using Continuous Processes to Increase Production

(2012) Neal G. Anderson   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Design and preparation of new palladium precatalysts for C–C and C–N cross-coupling reactions

(2012) Nicholas C. Bruno et al.   Chemical Science

Development of Preformed Pd Catalysts for Cross-Coupling Reactions, Beyond the 2010 Nobel Prize

(2012) Hongbo Li et al.   ACS Catalysis

Safe and Efficient Tetrazole Synthesis in a Continuous-Flow Microreactor

(2011) Prakash B. Palde et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis

(2011) Ryan L. Hartman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Continuous gas/liquid–liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination

(2011) Jessica R Breen et al.   Beilstein Journal of Organic Chemistry

From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

(2011) Santos Fustero et al.   CHEMICAL REVIEWS

Cross-coupling in flow

(2011) Timothy Noël et al.   CHEMICAL SOCIETY REVIEWS

Microwave-Assisted and Continuous Flow Multistep Synthesis of 4-(Pyrazol-1-yl)carboxanilides

(2011) David Obermayer et al.   JOURNAL OF ORGANIC CHEMISTRY

Piecing together the puzzle: understanding a mild, metal free reduction method for the large scale synthesis of hydrazines

(2011) Duncan L. Browne et al.   TETRAHEDRON

Indole synthesis: a review and proposed classification

(2011) Douglass F. Taber et al.   TETRAHEDRON

Palladium-Catalyzed Cross-Coupling of Aryl Chlorides and Tosylates with Hydrazine

(2010) Rylan J. Lundgren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two-Step Synthesis of Substituted 3-Aminoindazoles from 2-Bromobenzonitriles

(2010) Valerie Lefebvre et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Chemoselective Monoarylation of Hydrazides for the Synthesis of [1,2,4]Triazolo[4,3-a]pyridines

(2010) Andreas Reichelt et al.   ORGANIC LETTERS

Overcoming the Challenges of Solid Bridging and Constriction during Pd-Catalyzed C−N Bond Formation in Microreactors

(2010) Ryan L. Hartman et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous flow multi-step organic synthesis

(2010) Damien Webb et al.   Chemical Science

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

(2010) Timothy Noël et al.   Chemical Science

Dialkylbiaryl phosphines in Pd-catalyzed amination: a user's guide

(2010) David S. Surry et al.   Chemical Science

Energetic characteristics of transition metal complexes

(2009) Andrzej Wojewódka et al.   JOURNAL OF HAZARDOUS MATERIALS

CuI/4-Hydro-l-proline as a More Effective Catalytic System for Coupling of Aryl Bromides withN-Boc Hydrazine and Aqueous Ammonia

(2009) Liqin Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides

(2008) John F. Hartwig   ACCOUNTS OF CHEMICAL RESEARCH

Well-Defined N-Heterocyclic Carbenes−Palladium(II) Precatalysts for Cross-Coupling Reactions

(2008) Nicolas Marion et al.   ACCOUNTS OF CHEMICAL RESEARCH

Biaryl Phosphane Ligands in Palladium-Catalyzed Amination

(2008) David S. Surry et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Improved Regioselectivity in Pyrazole Formation through the Use of Fluorinated Alcohols as Solvents: Synthesis and Biological Activity of Fluorinated Tebufenpyrad Analogs

(2008) Santos Fustero et al.   JOURNAL OF ORGANIC CHEMISTRY

A Highly Active Catalyst for Pd-Catalyzed Amination Reactions: Cross-Coupling Reactions Using Aryl Mesylates and the Highly Selective Monoarylation of Primary Amines Using Aryl Chlorides

(2008) Brett P. Fors et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Benzo[4,5]imidazo[2,1-a]phthalazines: I. substituted o-nitrophenylhydrazines in the synthesis of phthalazin-1(2H)-ones

(2008) V. A. Kuznetsov et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY