标题
Protein Folding and Mechanisms of Proteostasis
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 16, Issue 8, Pages 17193-17230
出版商
MDPI AG
发表日期
2015-07-28
DOI
10.3390/ijms160817193
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Biology of Proteostasis in Aging and Disease
- (2015) Johnathan Labbadia et al. Annual Review of Biochemistry
- Mechanisms of Autophagy
- (2015) Nobuo N. Noda et al. Annual Review of Biophysics
- SnapShot: Intrinsic Structural Disorder
- (2015) Mainak Guharoy et al. CELL
- Protein Quality Control and Metabolism: Bidirectional Control in the Heart
- (2015) Zhao V. Wang et al. Cell Metabolism
- From local to global changes in proteins: a network view
- (2015) Laurent Vuillon et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Structure of a Single-Chain Fv Bound to the 17 N-Terminal Residues of Huntingtin Provides Insights into Pathogenic Amyloid Formation and Suppression
- (2015) Erwin De Genst et al. JOURNAL OF MOLECULAR BIOLOGY
- Molecular crowding effects on conformation and stability of G-quadruplex DNA structure: Insights from molecular dynamics simulation
- (2015) A. Verdian Doghaei et al. JOURNAL OF THEORETICAL BIOLOGY
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
- (2015) Samuel I A Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Intrinsic disorder of human Yin Yang 1 protein
- (2015) Andrzej Górecki et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
- (2015) Samuel I A Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Noncanonical binding of BiP ATPase domain to Ire1 and Perk is dissociated by unfolded protein CH1 to initiate ER stress signaling
- (2015) Marta Carrara et al. eLife
- Real-Time Dynamics of Emerging Actin Networks in Cell-Mimicking Compartments
- (2015) Siddharth Deshpande et al. PLoS One
- Chaperone-Targeting Cytotoxin and Endoplasmic Reticulum Stress-Inducing Drug Synergize to Kill Cancer Cells
- (2015) Joseph M. Backer et al. NEOPLASIA
- Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 3. Orchestrating the unfolded protein response in oncogenesis: an update
- (2014) Serge N. Manié et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 2. Protein misfolding and ER stress
- (2014) Joseph E. Chambers et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Differential Scales of Protein Quality Control
- (2014) Suzanne Wolff et al. CELL
- Human IAPP amyloidogenic properties and pancreatic β-cell death
- (2014) Marta S. Fernández CELL CALCIUM
- Protein chaperones: a composition of matter review (2008 – 2013)
- (2014) Tony Taldone et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Misfolded Polyglutamine, Polyalanine, and Superoxide Dismutase 1 Aggregate via Distinct Pathways in the Cell
- (2014) Saskia Polling et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The amyloid state and its association with protein misfolding diseases
- (2014) Tuomas P. J. Knowles et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
- (2014) Claudio Hetz et al. NATURE REVIEWS NEUROSCIENCE
- Local slowdown of translation by nonoptimal codons promotes nascent-chain recognition by SRP in vivo
- (2014) Sebastian Pechmann et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A second molecular biology revolution? The energy landscapes of biomolecular function
- (2014) Ruth Nussinov et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Dynamic JUNQ inclusion bodies are asymmetrically inherited in mammalian cell lines through the asymmetric partitioning of vimentin
- (2014) M. Ogrodnik et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Chaperone Functions in Protein Folding and Proteostasis
- (2013) Yujin E. Kim et al. Annual Review of Biochemistry
- Amyloid fibril formation of peptides derived from the C-terminus of CETP modulated by lipids
- (2013) Victor García-González et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- ER stress-induced cell death mechanisms
- (2013) Renata Sano et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Regulation of proteasome activity in health and disease
- (2013) Marion Schmidt et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Allostery in Disease and in Drug Discovery
- (2013) Ruth Nussinov et al. CELL
- The Cotranslational Function of Ribosome-Associated Hsp70 in Eukaryotic Protein Homeostasis
- (2013) Felix Willmund et al. CELL
- Chaperone-mediated autophagy: roles in disease and aging
- (2013) Ana Maria Cuervo et al. CELL RESEARCH
- Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis
- (2013) Andrija Finka et al. CELL STRESS & CHAPERONES
- Regulatory crosstalk within the mammalian unfolded protein response
- (2013) Joseph W. Brewer CELLULAR AND MOLECULAR LIFE SCIENCES
- Multisteric Regulation by Structural Disorder in Modular Signaling Proteins: An Extension of the Concept of Allostery
- (2013) Peter Tompa CHEMICAL REVIEWS
- Targeting endoplasmic reticulum stress in metabolic disease
- (2013) Stewart Siyan Cao et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Autophagic Processes in Yeast: Mechanism, Machinery and Regulation
- (2013) F. Reggiori et al. GENETICS
- Unfolded Protein Response Signaling and Metabolic Diseases
- (2013) Jaemin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Allosteric Effects in the Regulation of 26S Proteasome Activities
- (2013) Paweł Śledź et al. JOURNAL OF MOLECULAR BIOLOGY
- Single Molecule Characterization of the Interactions between Amyloid-β Peptides and the Membranes of Hippocampal Cells
- (2013) Priyanka Narayan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Cotranslational Ubiquitination Pathway for Quality Control of Misfolded Proteins
- (2013) Feng Wang et al. MOLECULAR CELL
- The Ribosome as a Hub for Protein Quality Control
- (2013) Sebastian Pechmann et al. MOLECULAR CELL
- Principles of Cotranslational Ubiquitination and Quality Control at the Ribosome
- (2013) Stefanie Duttler et al. MOLECULAR CELL
- Modulation of allostery by protein intrinsic disorder
- (2013) Allan Chris M. Ferreon et al. NATURE
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress
- (2013) Stéphanie Escusa-Toret et al. NATURE CELL BIOLOGY
- Targeting the unfolded protein response in disease
- (2013) Claudio Hetz et al. NATURE REVIEWS DRUG DISCOVERY
- Misfolded proteins join the Q
- (2013) Katharine H. Wrighton NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Autophagy in Human Health and Disease
- (2013) Augustine M.K. Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2
- (2013) L.-Q. Xu et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- The spatial structure of cell signaling systems
- (2013) Ruth Nussinov PHYSICAL BIOLOGY
- Chaperone activation by unfolding
- (2013) L. Foit et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Atomic structure and hierarchical assembly of a cross- amyloid fibril
- (2013) A. W. P. Fitzpatrick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- From Sequence and Forces to Structure, Function, and Evolution of Intrinsically Disordered Proteins
- (2013) Julie D. Forman-Kay et al. STRUCTURE
- Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins
- (2013) Prajwal Ciryam et al. Cell Reports
- Structural Basis of the Unfolded Protein Response
- (2012) Alexei Korennykh et al. Annual Review of Cell and Developmental Biology
- Diverse functional manifestations of intrinsic structural disorder in molecular chaperones
- (2012) Denes Kovacs et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Order out of Disorder: Working Cycle of an Intrinsically Unfolded Chaperone
- (2012) Dana Reichmann et al. CELL
- The Amyloid State of Proteins in Human Diseases
- (2012) David Eisenberg et al. CELL
- Aggregation of islet amyloid polypeptide: from physical chemistry to cell biology
- (2012) Ping Cao et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Small Molecules That Target Protein Misfolding
- (2012) Lori Krim Gavrin et al. JOURNAL OF MEDICINAL CHEMISTRY
- On the Possible Amyloid Origin of Protein Folds
- (2012) Jason Greenwald et al. JOURNAL OF MOLECULAR BIOLOGY
- Molecular Model of the Human 26S Proteasome
- (2012) Paula C.A. da Fonseca et al. MOLECULAR CELL
- The unfolded protein response: controlling cell fate decisions under ER stress and beyond
- (2012) Claudio Hetz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding
- (2012) Cecilia Andresen et al. NUCLEIC ACIDS RESEARCH
- Regular Patterns for Proteome-Wide Distribution of Protein Abundance across Species
- (2012) Fan Zhong et al. PLoS One
- Compartmentalization of superoxide dismutase 1 (SOD1G93A) aggregates determines their toxicity
- (2012) S. J. Weisberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective destruction of abnormal proteins by ubiquitin-mediated protein quality control degradation
- (2012) Eric K. Fredrickson et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Conditional disorder in chaperone action
- (2012) James C.A. Bardwell et al. TRENDS IN BIOCHEMICAL SCIENCES
- DnaK Functions as a Central Hub in the E. coli Chaperone Network
- (2012) Giulia Calloni et al. Cell Reports
- Unfolded Protein Responses With or Without Unfolded Proteins?
- (2012) Erik Snapp Cells
- Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Disorders
- (2011) Lale Ozcan et al. Annual Review of Medicine
- Structural analysis of the Sil1–Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor
- (2011) Ming Yan et al. BIOCHEMICAL JOURNAL
- Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1
- (2011) Alexei V Korennykh et al. BMC BIOLOGY
- Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions
- (2011) Heidi Olzscha et al. CELL
- Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy
- (2011) Yanfen Liu et al. CELL RESEARCH
- Sodium Phenylbutyrate, a Drug With Known Capacity to Reduce Endoplasmic Reticulum Stress, Partially Alleviates Lipid-Induced Insulin Resistance and β-Cell Dysfunction in Humans
- (2011) Changting Xiao et al. DIABETES
- Amyloidogenic Properties of a D/N Mutated 12 Amino Acid Fragment of the C-Terminal Domain of the Cholesteryl-Ester Transfer Protein (CETP)
- (2011) Victor García-González et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Unfolded protein response in cancer: the Physician's perspective
- (2011) Xuemei Li et al. Journal of Hematology & Oncology
- Intrinsic disorder in cell signaling and gene transcription
- (2011) Agnes Tantos et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways
- (2011) Thanyarat Promlek et al. MOLECULAR BIOLOGY OF THE CELL
- Disorder Targets Misorder in Nuclear Quality Control Degradation: A Disordered Ubiquitin Ligase Directly Recognizes Its Misfolded Substrates
- (2011) Joel C. Rosenbaum et al. MOLECULAR CELL
- Molecular chaperones in protein folding and proteostasis
- (2011) F. Ulrich Hartl et al. NATURE
- Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum
- (2011) M. H. Smith et al. SCIENCE
- Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis
- (2011) P. Tsaytler et al. SCIENCE
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- InterfERing with endoplasmic reticulum stress
- (2011) Honorata Kraskiewicz et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Protein Solubility and Protein Homeostasis: A Generic View of Protein Misfolding Disorders
- (2011) M. Vendruscolo et al. Cold Spring Harbor Perspectives in Biology
- Chemical and Biological Approaches for Adapting Proteostasis to Ameliorate Protein Misfolding and Aggregation Diseases-Progress and Prognosis
- (2011) S. L. Lindquist et al. Cold Spring Harbor Perspectives in Biology
- Understanding protein non-folding
- (2010) Vladimir N. Uversky et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
- (2010) Gökhan S. Hotamisligil CELL
- The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis
- (2010) Ira Tabas CIRCULATION RESEARCH
- Protein folding in the cell: challenges and progress
- (2010) Anne Gershenson et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women
- (2010) Marleen Kars et al. DIABETES
- -Cell Dysfunctional ERAD/Ubiquitin/Proteasome System in Type 2 Diabetes Mediated by Islet Amyloid Polypeptide-Induced UCH-L1 Deficiency
- (2010) S. Costes et al. DIABETES
- Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization
- (2010) Victor S. Van Laar et al. HUMAN MOLECULAR GENETICS
- A Small Molecule Inhibitor of Endoplasmic Reticulum Oxidation 1 (ERO1) with Selectively Reversible Thiol Reactivity
- (2010) Jaime D. Blais et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of basal cellular physiology by the homeostatic unfolded protein response
- (2010) D. Thomas Rutkowski et al. JOURNAL OF CELL BIOLOGY
- Gymnastics of Molecular Chaperones
- (2010) Matthias P. Mayer MOLECULAR CELL
- Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1
- (2010) R. Luke Wiseman et al. MOLECULAR CELL
- Autophagy and the Integrated Stress Response
- (2010) Guido Kroemer et al. MOLECULAR CELL
- A causative link between the structure of aberrant protein oligomers and their toxicity
- (2010) Silvia Campioni et al. Nature Chemical Biology
- Spatial organization and signal transduction at intercellular junctions
- (2010) Boryana N. Manz et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cellular strategies for controlling protein aggregation
- (2010) Jens Tyedmers et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Chaperone networks: Tipping the balance in protein folding diseases
- (2010) Cindy Voisine et al. NEUROBIOLOGY OF DISEASE
- Molecular chaperones antagonize proteotoxicity by differentially modulating protein aggregation pathways
- (2010) Peter M. Douglas et al. Prion
- Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering
- (2010) H. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Co- and post-translational modifications of the 26S proteasome in yeast
- (2010) Julia Kikuchi et al. PROTEOMICS
- Protein Folding in the Cytoplasm and the Heat Shock Response
- (2010) R. M. Vabulas et al. Cold Spring Harbor Perspectives in Biology
- Regulation Mechanisms and Signaling Pathways of Autophagy
- (2009) Congcong He et al. Annual Review of Genetics
- Variably modulated gating of the 26S proteasome by ATP and polyubiquitin
- (2009) Xiaohua Li et al. BIOCHEMICAL JOURNAL
- Close encounters of the third kind: disordered domains and the interactions of proteins
- (2009) Peter Tompa et al. BIOESSAYS
- Chemical Genomics Identifies the Unfolded Protein Response as a Target for Selective Cancer Cell Killing during Glucose Deprivation
- (2009) S. Saito et al. CANCER RESEARCH
- Imaging the Unfolded Protein Response in Primary Tumors Reveals Microenvironments with Metabolic Variations that Predict Tumor Growth
- (2009) M. T. Spiotto et al. CANCER RESEARCH
- IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates
- (2009) Dan Han et al. CELL
- Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance
- (2009) Lale Ozcan et al. Cell Metabolism
- Mammalian autophagy: core molecular machinery and signaling regulation
- (2009) Zhifen Yang et al. CURRENT OPINION IN CELL BIOLOGY
- Finding order within disorder: elucidating the structure of proteins associated with neurodegenerative disease
- (2009) Austin Huang et al. Future Medicinal Chemistry
- The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
- (2009) Kasper M.A. Rouschop et al. JOURNAL OF CLINICAL INVESTIGATION
- The Molecular Organization of the Fungal Prion HET-s in Its Amyloid Form
- (2009) Christian Wasmer et al. JOURNAL OF MOLECULAR BIOLOGY
- Disorder-to-order conformational transitions in protein structure and its relationship to disease
- (2009) Paola Mendoza-Espinosa et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Chaperonin overexpression promotes genetic variation and enzyme evolution
- (2009) Nobuhiko Tokuriki et al. NATURE
- Molecular mechanisms of proteasome assembly
- (2009) Shigeo Murata et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ELM: the status of the 2010 eukaryotic linear motif resource
- (2009) Cathryn M. Gould et al. NUCLEIC ACIDS RESEARCH
- The proteasome: Overview of structure and functions
- (2009) Keiji TANAKA PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles
- (2009) A. J. Schindler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chaperonin-mediated protein folding: using a central cavity to kinetically assist polypeptide chain folding
- (2009) Arthur L. Horwich et al. QUARTERLY REVIEWS OF BIOPHYSICS
- Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1
- (2009) S. D. Westerheide et al. SCIENCE
- TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
- (2009) M. Olivier et al. Cold Spring Harbor Perspectives in Biology
- An update on lipotoxic endoplasmic reticulum stress in pancreatic β-cells
- (2008) Miriam Cnop et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners
- (2008) Christopher J Oldfield et al. BMC GENOMICS
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- Chaperone machines in action
- (2008) Helen R Saibil CURRENT OPINION IN STRUCTURAL BIOLOGY
- Function and structure of inherently disordered proteins
- (2008) A Keith Dunker et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The Hsp90 Chaperone Machinery
- (2008) Sebastian Karl Wandinger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Misfolded proteins partition between two distinct quality control compartments
- (2008) Daniel Kaganovich et al. NATURE
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- The central unit within the 19S regulatory particle of the proteasome
- (2008) Rina Rosenzweig et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A multimeric assembly factor controls the formation of alternative 20S proteasomes
- (2008) Andrew R Kusmierczyk et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Contextual Specificity in Peptide-Mediated Protein Interactions
- (2008) Amelie Stein et al. PLoS One
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started