Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and Challenges
出版年份 2015 全文链接
标题
Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and Challenges
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 16, Issue 12, Pages 28614-28634
出版商
MDPI AG
发表日期
2015-12-02
DOI
10.3390/ijms161226119
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Modeling Familial Cancer with Induced Pluripotent Stem Cells
- (2015) Dung-Fang Lee et al. CELL
- Therapeutic genome editing: prospects and challenges
- (2015) David Benjamin Turitz Cox et al. NATURE MEDICINE
- Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency
- (2015) M. J. Ciancanelli et al. SCIENCE
- Modeling Viral Infectious Diseases and Development of Antiviral Therapies Using Human Induced Pluripotent Stem Cell-Derived Systems
- (2015) Marta Trevisan et al. Viruses-Basel
- Reprogramming with Small Molecules instead of Exogenous Transcription Factors
- (2015) Tongxiang Lin et al. Stem Cells International
- Using induced pluripotent stem cells as a tool for modelling carcinogenesis
- (2015) Emma L Curry World Journal of Stem Cells
- The generation of kidney organoids by differentiation of human pluripotent cells to ureteric bud progenitor–like cells
- (2014) Yun Xia et al. Nature Protocols
- Investigating human disease using stem cell models
- (2014) Jared L. Sterneckert et al. NATURE REVIEWS GENETICS
- Patient-Derived Skeletal Dysplasia Induced Pluripotent Stem Cells Display Abnormal Chondrogenic Marker Expression and Regulation by BMP2 and TGFβ1
- (2014) Biagio Saitta et al. STEM CELLS AND DEVELOPMENT
- Homologous recombination in human embryonic stem cells using CRISPR/Cas9 nickase and a long DNA donor template
- (2014) Zhili Rong et al. Protein & Cell
- Novel Insights into Disease Modeling Using Induced Pluripotent Stem Cells
- (2013) Toru Egashira et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- A 3D Alzheimer's disease culture model and the induction of P21-activated kinase mediated sensing in iPSC derived neurons
- (2013) Dawei Zhang et al. BIOMATERIALS
- One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
- (2013) Haoyi Wang et al. CELL
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
- (2013) F. Ann Ran et al. CELL
- Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging
- (2013) Justine D. Miller et al. Cell Stem Cell
- Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome
- (2013) Milena Bellin et al. EMBO JOURNAL
- A Novel Model of Urinary Tract Differentiation, Tissue Regeneration, and Disease: Reprogramming Human Prostate and Bladder Cells into Induced Pluripotent Stem Cells
- (2013) Mohammad Moad et al. EUROPEAN UROLOGY
- Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells
- (2013) Su Mi Choi et al. HEPATOLOGY
- Vascularized and functional human liver from an iPSC-derived organ bud transplant
- (2013) Takanori Takebe et al. NATURE
- Cerebral organoids model human brain development and microcephaly
- (2013) Madeline A. Lancaster et al. NATURE
- CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
- (2013) Prashant Mali et al. NATURE BIOTECHNOLOGY
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
- (2013) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- Efficient Generation of Rat Induced Pluripotent Stem Cells Using a Non-Viral Inducible Vector
- (2013) Claudia Merkl et al. PLoS One
- Generation of systemic lupus erythematosus-specific induced pluripotent stem cells from urine
- (2013) Yuyu Chen et al. RHEUMATOLOGY INTERNATIONAL
- Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds
- (2013) P. Hou et al. SCIENCE
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- An iPSC Line from Human Pancreatic Ductal Adenocarcinoma Undergoes Early to Invasive Stages of Pancreatic Cancer Progression
- (2013) Jungsun Kim et al. Cell Reports
- Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples
- (2012) K. Kumano et al. BLOOD
- Disease characterization using LQTS-specific induced pluripotent stem cells
- (2012) Toru Egashira et al. CARDIOVASCULAR RESEARCH
- Induced pluripotent stem cells as a tool for gaining new insights into Fanconi anemia
- (2012) Lars U.W. Müller et al. CELL CYCLE
- Erosion of Dosage Compensation Impacts Human iPSC Disease Modeling
- (2012) Shila Mekhoubad et al. Cell Stem Cell
- Induced pluripotent stem cells generated from diabetic patients with mitochondrial DNA A3243G mutation
- (2012) J. Fujikura et al. DIABETOLOGIA
- Modeling neurogenesis impairment in down syndrome with induced pluripotent stem cells from Trisomy 21 amniotic fluid cells
- (2012) Huai-En Lu et al. EXPERIMENTAL CELL RESEARCH
- Applications of Patient-Specific Induced Pluripotent Stem Cells; Focused on Disease Modeling, Drug Screening and Therapeutic Potentials for Liver Disease
- (2012) Yong Soon Chun et al. International Journal of Biological Sciences
- Generation of Induced Pluripotent Stem Cells from Human Amniotic Fluid Cells by Reprogramming with Two Factors in Feeder-free Conditions
- (2012) Qing LI et al. JOURNAL OF REPRODUCTION AND DEVELOPMENT
- Modeling of Catecholaminergic Polymorphic Ventricular Tachycardia With Patient-Specific Human-Induced Pluripotent Stem Cells
- (2012) Ilanit Itzhaki et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells
- (2012) Fabien G. Lafaille et al. NATURE
- Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
- (2012) Mason A. Israel et al. NATURE
- FLASH assembly of TALENs for high-throughput genome editing
- (2012) Deepak Reyon et al. NATURE BIOTECHNOLOGY
- Modeling disease mutations by gene targeting in one-cell mouse embryos
- (2012) M. Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- iPSC Disease Modeling
- (2012) F. Soldner et al. SCIENCE
- Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy
- (2012) N. Sun et al. Science Translational Medicine
- Induced Pluripotent Stem Cells from Human Hair Follicle Mesenchymal Stem Cells
- (2012) Yimei Wang et al. Stem Cell Reviews and Reports
- Derivation and Functional Analysis of Patient-Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease
- (2012) Yan Jiang et al. STEM CELLS
- Induced Pluripotency and Oncogenic Transformation Are Related Processes
- (2012) John W. Riggs et al. STEM CELLS AND DEVELOPMENT
- The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis
- (2012) Xiao-Ming Wang et al. Stem Cell Research & Therapy
- Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington’s disease patient cells
- (2012) Tarja A Juopperi et al. Molecular Brain
- Modeling and Rescue of the Vascular Phenotype of Williams-Beuren Syndrome in Patient Induced Pluripotent Stem Cells
- (2012) Caroline Kinnear et al. Stem Cells Translational Medicine
- Generation of Human Induced Pluripotent Stem Cells from Peripheral Blood Using the STEMCCA Lentiviral Vector
- (2012) Andreia Gianotti Sommer et al. Jove-Journal of Visualized Experiments
- Targeting DNA With Fingers and TALENs
- (2012) Daniel F Carlson et al. Molecular Therapy-Nucleic Acids
- The generation of iPS cells using non-viral magnetic nanoparticlebased transfection
- (2011) Chang Hyun Lee et al. BIOMATERIALS
- Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
- (2011) Frank Soldner et al. CELL
- LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
- (2011) Ha Nam Nguyen et al. Cell Stem Cell
- Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture
- (2011) Louise C. Laurent et al. Cell Stem Cell
- Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency
- (2011) Frederick Anokye-Danso et al. Cell Stem Cell
- Meganucleases and Other Tools for Targeted Genome Engineering: Perspectives and Challenges for Gene Therapy
- (2011) George Silva et al. CURRENT GENE THERAPY
- Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells
- (2011) Luis F. Z. Batista et al. NATURE
- Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease
- (2011) Philipp Koch et al. NATURE
- Somatic coding mutations in human induced pluripotent stem cells
- (2011) Athurva Gore et al. NATURE
- Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
- (2011) Masayuki Yazawa et al. NATURE
- Modelling the long QT syndrome with induced pluripotent stem cells
- (2011) Ilanit Itzhaki et al. NATURE
- Self-organizing optic-cup morphogenesis in three-dimensional culture
- (2011) Mototsugu Eiraku et al. NATURE
- Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
- (2011) Yuki Ohi et al. NATURE CELL BIOLOGY
- Cellular Reprogramming: A New Technology Frontier in Pharmaceutical Research
- (2011) Amy Brock et al. PHARMACEUTICAL RESEARCH
- Modeling Retinal Degeneration Using Patient-Specific Induced Pluripotent Stem Cells
- (2011) Zi-Bing Jin et al. PLoS One
- Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome
- (2011) Steven D. Sheridan et al. PLoS One
- Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues
- (2010) Jacob H. Hanna et al. CELL
- Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds
- (2010) Saiyong Zhu et al. Cell Stem Cell
- Friedreich's Ataxia Induced Pluripotent Stem Cells Model Intergenerational GAA⋅TTC Triplet Repeat Instability
- (2010) Sherman Ku et al. Cell Stem Cell
- Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells
- (2010) Miguel Angel Esteban et al. Cell Stem Cell
- Reprogramming of T Cells from Human Peripheral Blood
- (2010) Yuin-Han Loh et al. Cell Stem Cell
- Reprogramming of Human Peripheral Blood Cells to Induced Pluripotent Stem Cells
- (2010) Judith Staerk et al. Cell Stem Cell
- Generation of Induced Pluripotent Stem Cells from Human Terminally Differentiated Circulating T Cells
- (2010) Tomohisa Seki et al. Cell Stem Cell
- Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
- (2010) Luigi Warren et al. Cell Stem Cell
- A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects
- (2010) Jinqiu Zhang et al. Cell Stem Cell
- Targeting DNA Double-Strand Breaks with TAL Effector Nucleases
- (2010) M. Christian et al. GENETICS
- Induced Pluripotent Stem Cells Can Be Used to Model the Genomic Imprinting Disorder Prader-Willi Syndrome
- (2010) Jiayin Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells
- (2010) S. Tamir Rashid et al. JOURNAL OF CLINICAL INVESTIGATION
- Generation of HIV-1 Resistant and Functional Macrophages From Hematopoietic Stem Cell–derived Induced Pluripotent Stem Cells
- (2010) Amal Kambal et al. MOLECULAR THERAPY
- Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
- (2010) Xonia Carvajal-Vergara et al. NATURE
- Epigenetic memory in induced pluripotent stem cells
- (2010) K. Kim et al. NATURE
- The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
- (2010) Josiane E. Garneau et al. NATURE
- A TALE nuclease architecture for efficient genome editing
- (2010) Jeffrey C Miller et al. NATURE BIOTECHNOLOGY
- Epigenetic modifications in pluripotent and differentiated cells
- (2010) Alexander Meissner NATURE BIOTECHNOLOGY
- Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome
- (2010) Alessandra Moretti et al. NEW ENGLAND JOURNAL OF MEDICINE
- Activation of Pluripotency Genes in Human Fibroblast Cells by a Novel mRNA Based Approach
- (2010) Jordan R. Plews et al. PLoS One
- High-Efficient Generation of Induced Pluripotent Stem Cells from Human Astrocytes
- (2010) Sergio Ruiz et al. PLoS One
- Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader–Willi syndromes
- (2010) Stormy J. Chamberlain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells
- (2010) Arefeh Ghodsizadeh et al. Stem Cell Reviews and Reports
- Generation of Induced Pluripotent Stem Cells from Human Adipose-Derived Stem Cells Without c-MYC
- (2010) Tetsuhiro Aoki et al. TISSUE ENGINEERING PART A
- Mechanisms of Stem Cell Self-Renewal
- (2009) He Shenghui et al. Annual Review of Cell and Developmental Biology
- Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders
- (2009) Z. Ye et al. BLOOD
- Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
- (2009) Frank Soldner et al. CELL
- A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog
- (2009) Justin K. Ichida et al. Cell Stem Cell
- Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins
- (2009) Dohoon Kim et al. Cell Stem Cell
- Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins
- (2009) Hongyan Zhou et al. Cell Stem Cell
- A chemical platform for improved induction of human iPSCs
- (2009) Tongxiang Lin et al. NATURE METHODS
- Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon
- (2009) Kosuke Yusa et al. NATURE METHODS
- Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease
- (2009) Sylvestre Grizot et al. NUCLEIC ACIDS RESEARCH
- Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
- (2009) Noemi FUSAKI et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4
- (2009) C. A. Lyssiotis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
- (2009) J. Yu et al. SCIENCE
- Polycistronic Lentiviral Vector for “Hit and Run” Reprogramming of Adult Skin Fibroblasts to Induced Pluripotent Stem Cells
- (2009) Chia-Wei Chang et al. STEM CELLS
- Adenoviral Gene Delivery Can Reprogram Human Fibroblasts to Induced Pluripotent Stem Cells
- (2009) Wenbo Zhou et al. STEM CELLS
- Context-dependent DNA recognition code for C2H2 zinc-finger transcription factors
- (2008) J. Liu et al. BIOINFORMATICS
- Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency
- (2008) Jacob Hanna et al. CELL
- Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells
- (2008) David J. Wong et al. Cell Stem Cell
- A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells
- (2008) Nimet Maherali et al. Cell Stem Cell
- Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds
- (2008) Yan Shi et al. Cell Stem Cell
- Zinc-finger Nucleases: The Next Generation Emerges
- (2008) Toni Cathomen et al. MOLECULAR THERAPY
- Induced pluripotent stem cells from a spinal muscular atrophy patient
- (2008) Allison D. Ebert et al. NATURE
- Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
- (2008) Trond Aasen et al. NATURE BIOTECHNOLOGY
- Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
- (2008) Elena E Perez et al. NATURE BIOTECHNOLOGY
- Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
- (2008) Danwei Huangfu et al. NATURE BIOTECHNOLOGY
- Marked differences in differentiation propensity among human embryonic stem cell lines
- (2008) Kenji Osafune et al. NATURE BIOTECHNOLOGY
- Unexpected failure rates for modular assembly of engineered zinc fingers
- (2008) Cherie L Ramirez et al. NATURE METHODS
- Induced Pluripotent Stem Cells Generated Without Viral Integration
- (2008) M. Stadtfeld et al. SCIENCE
- Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
- (2008) K. Okita et al. SCIENCE
- Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
- (2008) J. T. Dimos et al. SCIENCE
- Reprogramming of Neural Progenitor Cells into Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 Expression
- (2008) Sarah Eminli et al. STEM CELLS
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