Review
Chemistry, Multidisciplinary
Vittorio Scardaci
Summary: This paper reviews the synthesis of anisotropic silver nanoparticles, focusing on the factors influencing the process and the role of key molecules like citrate. The different synthesis pathways lead to distinct reaction processes, with proposed applications for the nanoparticles obtained by these methods.
Article
Polymer Science
Panagiotis G. Georgiou, Collette S. Guy, Muhammad Hasan, Ashfaq Ahmad, Sarah-Jane Richards, Alexander N. Baker, Neer Thakkar, Marc Walker, Sarojini Pandey, Neil R. Anderson, Dimitris Grammatopoulos, Matthew Gibson
Summary: The COVID-19 pandemic has emphasized the importance of innovative biosensing, diagnostic, and surveillance platforms. This study demonstrates that glycosylated, polymer-stabilized, gold nanorods can bind to the SARS-CoV-2 spike protein and correlate with the presence of the virus in COVID-19 clinical samples. The use of polymer tethering of glycans shows promise for plasmonic biosensors in infection detection.
Article
Chemistry, Multidisciplinary
Jinlong Shao, Yating Cui, Ye Liang, Hong Liu, Baojin Ma, Shaohua Ge
Summary: The study aimed to reduce the cytotoxicity of silver (Ag) while maintaining its antibacterial properties through a two-layered membrane structure. Adjusting the thickness ratio achieved high cytocompatibility on the silk fibroin (SF) side while maintaining strong antibacterial properties.
Article
Materials Science, Multidisciplinary
Efren Gonzalez-Aguinaga, Pablo Eduardo Cardoso-Avila, Rita Patakfalvi, Fernando Pedro-Garcia
Summary: Anisotropic silver nanoparticles (AgNPs) were synthesized by phototransformation of spherical seed nanoparticles using LEDs of five different wavelengths. The catalytic activity of these AgNPs was compared to evaluate the effect of size and morphology, while keeping the surface chemistry constant. Characterization techniques such as UV-vis spectroscopy, SEM, DLS, and Z-potential were used, and the AgNPs were tested in the catalytic reduction of methylene blue. The results showed that the sample phototransformed with 500 nm LEDs exhibited the best catalytic performance, as determined by pseudo-first order kinetics.
Article
Chemistry, Physical
Ami Yoo, Mengshi Lin, Azlin Mustapha
Summary: The study found that ZnO and Ag NPs have mild inhibitory effects on intestinal bacteria, affecting cell numbers and morphology during incubation, but with minimal leakage of cellular content and more cells observed to be alive after exposure to the NPs.
Article
Pharmacology & Pharmacy
Tahmina Monowar, Md. Sayedur Rahman, Subhash J. Bhore, Kathiresan V. Sathasivam
Summary: This study synthesized silver nanoparticles (AgNPs) using an endophytic bacterial strain and evaluated their antimicrobial potential against pathogenic and multidrug-resistant microbes. The results demonstrated that the AgNPs showed promising antimicrobial activity against a range of pathogens and MDR bacteria.
Article
Spectroscopy
Ashkan Bahadoran, Mahmoud Khoshnoudi Jabarabadi, Zaid Hameed Mahmood, Dmitry Bokov, Baadal Jushi Janani, Ali Fakhri
Summary: In this project, poly (citric acid) functionalized nano Ag/Cu was synthesized for rapid detection of cysteine and Streptococcus pneumoniae. The prepared nano probe exhibited high sensitivity and detection limit, showcasing its significance for food safety and human health.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Biotechnology & Applied Microbiology
Abdulkader Masri, Sumayah Abdelnasir, Ayaz Anwar, Javed Iqbal, Arshid Numan, Priyanka Jagadish, Syed Shahabuddin, Mohammad Khalid
Summary: This study demonstrated the strong antimicrobial effects of a ternary nanocomposite containing conducting polymer polypyrrole, cobalt oxide, and silver nanoparticles against drug-resistant bacteria and a protist, while showing minimal cytotoxicity against human cells. These results suggest the potential of PPy-Co3O4-AgNPs in developing novel antimicrobial nanomaterials for biomedical applications.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Mantas Sriubas, Kristina Bockute, Paulius Palevicius, Marius Kaminskas, Zilvinas Rinkevicius, Minvydas Ragulskis, Sandrita Simonyte, Modestas Ruzauskas, Giedrius Laukaitis
Summary: Metal-based nanoparticles decorated TiO2 thin films show promising antibacterial activity against bacteria associated with oral diseases. The size and spacing of nanoparticles play a crucial role in determining the antibacterial efficacy. In addition, the presence of bacteria can be observed and identified using deep learning techniques.
Article
Veterinary Sciences
Saengrawee Thammawithan, Pawinee Siritongsuk, Sawinee Nasompag, Sakda Daduang, Sompong Klaynongsruang, Nuvee Prapasarakul, Rina Patramanon
Summary: This study demonstrates that anisotropic silver nanoparticles exhibit effective antibacterial activity against bacterial pathogens with low cytotoxicity to skin cells, and can be formulated into a gel for treating wound infections. The anisotropic AgNPs show long-term antibacterial protection compared to povidone iodine, suggesting their potential as an alternative antimicrobial agent for treating bacterial skin infections and promoting wound healing.
VETERINARY SCIENCES
(2021)
Article
Engineering, Environmental
La Phan Phuong Ha, Tran Hoang The Vinh, Nguyen Thi Be Thuy, Cao Minh Thi, Pham Van Viet
Summary: The combination of noble metals and semiconductors can create an efficient photocatalyst for degrading organic pollutants with visible light activation. In this study, Ag/ZnO nanorods were synthesized and showed superior photocatalytic activity compared to bare ZnO nanorods, thanks to the enhanced separation of electron-hole pairs and the localized surface plasmon resonance effect derived from silver nanoparticles.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Analytical
Marwa Ahmed El-Naka, A. El-Dissouky, G. Y. Ali, Shaker Ebrahim, Azza Shokry
Summary: A fluorescent biosensor based on garlic capped Ag nanoparticles has been synthesized for cholesterol detection. The sensor showed good performance with high selectivity and accuracy in detecting cholesterol in complex samples.
Article
Chemistry, Multidisciplinary
Duaa R. Ibraheem, Nehia N. Hussein, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Riaz A. Khan, Osamah Al Rugaie
Summary: In this study, silver nanoparticles (AgNPs) with antibacterial properties were successfully synthesized using the chemical reduction method, and the antibiotic ciprofloxacin (CIP) was loaded onto the AgNPs to enhance its antibacterial activity. The new nanocomposite, AgNPs-PEG-CIP, showed higher antibacterial, antibiofilm, and antioxidant activity against the tested pathogenic bacteria compared to CIP alone, indicating its potential as an antibacterial agent.
Article
Biophysics
Sandra Montalvo-Quiros, Sergio Gomez-Grana, Maria Vallet-Regi, Rafael C. Prados-Rosales, Blanca Gonzalez, Jose L. Luque-Garcia
Summary: Tuberculosis remains a major public health issue with a lack of effective vaccine and the emergence of highly antibiotic-resistant strains of Mycobacterium tuberculosis. Silver nanoparticles show high bactericidal efficacy, but their relatively high toxicity calls for the design of nanocarriers for safe delivery. Mesoporous silica nanoparticles have been used as carriers for silver nanoparticles as antimycobacterial agents, demonstrating good capability against Mtb with different synthetic approaches.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Xinting Cheng, Xibo Pei, Wenjia Xie, Junyu Chen, Yuanyuan Li, Jian Wang, Huile Gao, Qianbing Wan
Summary: This study successfully synthesized silver nanoparticles with pH sensitive charge reversal and self-aggregation capacities, and applied them in animal models. The nanoparticles showed antibacterial effects, inhibited plaque biofilm formation, and improved inflammatory responses.
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)