标题
Hypoxia-sensitive pathways in inflammation-driven fibrosis
作者
关键词
-
出版物
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
Volume 307, Issue 12, Pages R1369-R1380
出版商
American Physiological Society
发表日期
2014-10-09
DOI
10.1152/ajpregu.00349.2014
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- miR-210 promotes IPF fibroblast proliferation in response to hypoxia
- (2014) Vidya Bodempudi et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Emerging therapeutic interventions for idiopathic pulmonary fibrosis
- (2014) Sushmita Chakraborty et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase
- (2014) X. Zheng et al. GENES & DEVELOPMENT
- Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation
- (2014) Eric L. Campbell et al. IMMUNITY
- Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling
- (2014) Xiwu Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury
- (2014) Pinelopi P. Kapitsinou et al. JOURNAL OF CLINICAL INVESTIGATION
- Regulation of Wound Healing and Fibrosis by Hypoxia and Hypoxia-Inducible Factor-1
- (2014) Robin J Ruthenborg et al. MOLECULES AND CELLS
- Pro-resolving lipid mediators are leads for resolution physiology
- (2014) Charles N. Serhan NATURE
- A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis
- (2014) Talmadge E. King et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis
- (2014) Luca Richeldi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Treatment of inflammatory bowel disease (IBD)
- (2014) Anand B. Pithadia et al. Pharmacological Reports
- The In Vivo Fibrotic Role of FIZZ1 in Pulmonary Fibrosis
- (2014) Tianju Liu et al. PLoS One
- Integrins and cadherins as therapeutic targets in fibrosis
- (2014) Sandeep K. Agarwal Frontiers in Pharmacology
- Cellular and molecular mechanisms in the hypoxic tissue: role of HIF-1 and ROS
- (2013) Andrea B. Zepeda et al. CELL BIOCHEMISTRY AND FUNCTION
- Hypoxia-inducible factor (HIF) network: insights from mathematical models
- (2013) Miguel AS Cavadas et al. Cell Communication and Signaling
- Targeting the HIF pathway in inflammation and immunity
- (2013) Carsten C Scholz et al. CURRENT OPINION IN PHARMACOLOGY
- A dynamic model of the hypoxia-inducible factor 1 (HIF-1 ) network
- (2013) L. K. Nguyen et al. JOURNAL OF CELL SCIENCE
- The Wound Healing Process: An Overview of the Cellular and Molecular Mechanisms
- (2013) T Velnar et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- Lipoxins Attenuate Renal Fibrosis by Inducing let-7c and Suppressing TGF R1
- (2013) E. P. Brennan et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Diabetic nephropathy: are there new and potentially promising therapies targeting oxygen biology?
- (2013) Toshio Miyata et al. KIDNEY INTERNATIONAL
- Hydroxylases as therapeutic targets in inflammatory bowel disease
- (2013) Eoin P Cummins et al. LABORATORY INVESTIGATION
- The complexity of NF-κB signaling in inflammation and cancer
- (2013) Bastian Hoesel et al. Molecular Cancer
- Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3
- (2013) Malcolm Whitman et al. NATURE MEDICINE
- Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3
- (2013) Hikaru Sugimoto et al. NATURE MEDICINE
- New Therapies for Diabetic Kidney Disease
- (2013) Jonathan Himmelfarb et al. NEW ENGLAND JOURNAL OF MEDICINE
- Regulation of IL-1 -induced NF- B by hydroxylases links key hypoxic and inflammatory signaling pathways
- (2013) C. C. Scholz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypoxia and Integrin-Mediated Epithelial Restitution during Mucosal Inflammation
- (2013) Bridie J. Goggins et al. Frontiers in Immunology
- Critical Role of Transforming Growth Factor Beta in Different Phases of Wound Healing
- (2013) Mohammadreza Pakyari et al. Advances in Wound Care
- Slowing progression of chronic kidney disease
- (2013) Paul E. Drawz et al. Kidney International Supplements
- Sequential expression of IGF-IB followed by active TGF-β1 induces synergistic pulmonary fibroproliferation in vivo
- (2012) Graciela Andonegui et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- TGF-β signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities
- (2012) Rohan Samarakoon et al. CELLULAR SIGNALLING
- The evolving pharmacotherapy of pulmonary fibrosis
- (2012) Harpreet K Lota et al. EXPERT OPINION ON PHARMACOTHERAPY
- Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation
- (2012) Hui Yao Lan International Journal of Biological Sciences
- Activation of Wnt11 by Transforming Growth Factor-β Drives Mesenchymal Gene Expression through Non-canonical Wnt Protein Signaling in Renal Epithelial Cells
- (2012) Peng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis
- (2012) Hikaru Sugimoto et al. NATURE MEDICINE
- Mechanisms of fibrosis: therapeutic translation for fibrotic disease
- (2012) Thomas A Wynn et al. NATURE MEDICINE
- TGF-β and NF-κB signal pathway cross-talk is mediated through TAK1 and SMAD7 in a subset of head and neck cancers
- (2012) C Freudlsperger et al. ONCOGENE
- Loss of Endogenous Bone Morphogenetic Protein-6 Aggravates Renal Fibrosis
- (2011) Amélie Dendooven et al. AMERICAN JOURNAL OF PATHOLOGY
- Themes in fibrosis and gastrointestinal inflammation
- (2011) Claudio Fiocchi et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Hypoxia-inducible factor-1α mediates TGF-β-induced PAI-1 production in alveolar macrophages in pulmonary fibrosis
- (2011) Manabu Ueno et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Daikenchuto, a Kampo Medicine, Regulates Intestinal Fibrosis Associated with Decreasing Expression of Heat Shock Protein 47 and Collagen Content in a Rat Colitis Model
- (2011) Ken Inoue et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- NFκB and HIF display synergistic behaviour during hypoxic inflammation
- (2011) Ulrike Bruning et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Lipoxin A4 and benzo-lipoxin A4 attenuate experimental renal fibrosis
- (2011) Emma Börgeson et al. FASEB JOURNAL
- Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis
- (2011) Qiyuan Zhou et al. FASEB JOURNAL
- TGF-β signaling in fibrosis
- (2011) Anna Biernacka et al. GROWTH FACTORS
- Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis
- (2011) Carlos Medina et al. JOURNAL OF PATHOLOGY
- Pirfenidone for Diabetic Nephropathy
- (2011) K. Sharma et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Inflammation meets cancer, with NF-κB as the matchmaker
- (2011) Yinon Ben-Neriah et al. NATURE IMMUNOLOGY
- Transient hypoxia-inducible factor activation in rat renal ablation and reduced fibrosis with L-mimosine
- (2011) XIAOFANG YU et al. NEPHROLOGY
- Analysis of intestinal fibrosis in chronic colitis in mice induced by dextran sulfate sodium
- (2011) Kenji Suzuki et al. PATHOLOGY INTERNATIONAL
- The Hydroxylase Inhibitor Dimethyloxallyl Glycine Attenuates Endotoxic Shock Via Alternative Activation of Macrophages and IL-10 Production by B1 Cells
- (2011) Emily Hams et al. SHOCK
- Platelets, inflammation and tissue regeneration
- (2011) Alan Nurden THROMBOSIS AND HAEMOSTASIS
- Oxygen in acute and chronic wound healing
- (2010) S. Schreml et al. BRITISH JOURNAL OF DERMATOLOGY
- Smad3 Signaling Critically Regulates Fibroblast Phenotype and Function in Healing Myocardial Infarction
- (2010) Marcin Dobaczewski et al. CIRCULATION RESEARCH
- Loss of Prolyl Hydroxylase-1 Protects Against Colitis Through Reduced Epithelial Cell Apoptosis and Increased Barrier Function
- (2010) Murtaza M. Tambuwala et al. GASTROENTEROLOGY
- Cellular and molecular basis for the regulation of inflammation by TGF-
- (2010) A. Yoshimura et al. JOURNAL OF BIOCHEMISTRY
- Factors Affecting Wound Healing
- (2010) S. Guo et al. JOURNAL OF DENTAL RESEARCH
- An Intact Canonical NF- B Pathway Is Required for Inflammatory Gene Expression in Response to Hypoxia
- (2010) S. F. Fitzpatrick et al. JOURNAL OF IMMUNOLOGY
- Hydroxylase Inhibition Abrogates TNF- -Induced Intestinal Epithelial Damage by Hypoxia-Inducible Factor-1-Dependent Repression of FADD
- (2010) P. Hindryckx et al. JOURNAL OF IMMUNOLOGY
- Macrophages: Master Regulators of Inflammation and Fibrosis
- (2010) Thomas Wynn et al. SEMINARS IN LIVER DISEASE
- Extracellular BMP-antagonist regulation in development and disease: tied up in knots
- (2010) David W. Walsh et al. TRENDS IN CELL BIOLOGY
- Reduced liver fibrosis in hypoxia-inducible factor-1α-deficient mice
- (2009) Jeon-OK Moon et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- The Role of NF-κB in Hypoxia-Induced Gene Expression
- (2009) Cormac T. Taylor et al. Annals of the New York Academy of Sciences
- Requirement of transforming growth factor β-activated kinase 1 for transforming growth factor β-induced α-smooth muscle actin expression and extracellular matrix contraction in fibroblasts
- (2009) Xu Shi-Wen et al. ARTHRITIS AND RHEUMATISM
- Lipoxins: resolutionary road
- (2009) Paola Maderna et al. BRITISH JOURNAL OF PHARMACOLOGY
- Noncanonical transforming growth factor β signaling in scleroderma fibrosis
- (2009) Maria Trojanowska CURRENT OPINION IN RHEUMATOLOGY
- Regulation of Angiogenesis by Oxygen and Metabolism
- (2009) Peter Fraisl et al. DEVELOPMENTAL CELL
- Biological Therapies for Inflammatory Bowel Diseases
- (2009) Paul Rutgeerts et al. GASTROENTEROLOGY
- Increased Short- and Long-Term Risk of Inflammatory Bowel Disease After Salmonella or Campylobacter Gastroenteritis
- (2009) Kim O. Gradel et al. GASTROENTEROLOGY
- Transforming growth factor signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures
- (2009) A Di Sabatino et al. GUT
- ATLa, an Aspirin-Triggered Lipoxin A4 Synthetic Analog, Prevents the Inflammatory and Fibrotic Effects of Bleomycin-Induced Pulmonary Fibrosis
- (2009) V. Martins et al. JOURNAL OF IMMUNOLOGY
- Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney
- (2009) Y. R. Song et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Hypoxia. Regulation of NFκB signalling during inflammation: the role of hydroxylases
- (2009) Kathryn M Oliver et al. ARTHRITIS RESEARCH & THERAPY
- Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets
- (2008) Johanna Myllyharju ANNALS OF MEDICINE
- Turn me on: regulating HIF transcriptional activity
- (2008) K Lisy et al. CELL DEATH AND DIFFERENTIATION
- TGF-β coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival
- (2008) Anne Gingery et al. EXPERIMENTAL CELL RESEARCH
- Current Directions in IBD Therapy: What Goals Are Feasible With Biological Modifiers?
- (2008) William J. Sandborn GASTROENTEROLOGY
- Inhibition of the renin–angiotensin system and chronic kidney disease
- (2008) Kostas C. Siamopoulos et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- Wound repair and regeneration
- (2008) Geoffrey C. Gurtner et al. NATURE
- Mitochondria and cellular oxygen sensing in the HIF pathway
- (2007) Cormac T. Taylor BIOCHEMICAL JOURNAL
- The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis
- (2007) Eoin P. Cummins et al. GASTROENTEROLOGY
- Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition
- (2007) Andreas Robinson et al. GASTROENTEROLOGY
- Progressive pulmonary fibrosis is mediated by TGF-β isoform 1 but not TGF-β3
- (2007) Kjetil Ask et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More