NF-κB and STAT1 control CXCL1 and CXCL2 gene transcription

The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis

(2013) Lindsey E. Padgett et al.   Annals of the New York Academy of Sciences

Plasma Levels of CXCL1 (GRO-α) and CXCL10 (IP-10) are Elevated in Type 2 Diabetic Patients: Evidence for the Involvement of Inflammation and Angiogenesis / Angiostasis in this Disease State

(2013) Seyyed Sajadi et al.   Clinical Laboratory

Administration of IL-1 Trap prolongs survival of transplanted pancreatic islets to type 1 diabetic NOD mice

(2013) Tobias Rydgren et al.   CYTOKINE

Reduction of Circulating Neutrophils Precedes and Accompanies Type 1 Diabetes

(2013) A. Valle et al.   DIABETES

Synergistic Expression of the CXCL10 Gene in Response to IL-1  and IFN-  Involves NF- B, Phosphorylation of STAT1 at Tyr701, and Acetylation of Histones H3 and H4

(2013) S. J. Burke et al.   JOURNAL OF IMMUNOLOGY

Regulation of iNOS Gene Transcription by IL-1β and IFN-γ Requires a Coactivator Exchange Mechanism

(2013) Susan J. Burke et al.   MOLECULAR ENDOCRINOLOGY

Mechanisms of disease: inflammasome activation and the development of type 2 diabetes

(2013) Ryan W. Grant et al.   Frontiers in Immunology

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation

(2012) Kosei Eguchi et al.   Cell Metabolism

Human Islets Express a Marked Proinflammatory Molecular Signature Prior to Transplantation

(2012) Mark J. Cowley et al.   CELL TRANSPLANTATION

The RNA polymerase II CTD coordinates transcription and RNA processing

(2012) J.-P. Hsin et al.   GENES & DEVELOPMENT

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

Common and specific signatures of gene expression and protein–protein interactions in autoimmune diseases

(2012) T Tuller et al.   GENES AND IMMUNITY

The role of neutrophils in autoimmune diseases

(2012) Tamás Németh et al.   IMMUNOLOGY LETTERS

Turning Receptors On and Off with Intracellular Pepducins: New Insights into G-protein-coupled Receptor Drug Development

(2012) Katie O'Callaghan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCR1/2 inhibition enhances pancreatic islet survival after transplantation

(2012) Antonio Citro et al.   JOURNAL OF CLINICAL INVESTIGATION

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes

(2012) Julien Diana et al.   NATURE MEDICINE

Regulation of the CCL2 Gene in Pancreatic β-Cells by IL-1β and Glucocorticoids: Role of MKP-1

(2012) Susan J. Burke et al.   PLoS One

The gene encoding cyclooxygenase-2 is regulated by IL-1β and prostaglandins in 832/13 rat insulinoma cells

(2011) Susan J. Burke et al.   CELLULAR IMMUNOLOGY

Expression and Regulation of Chemokines in Murine and Human Type 1 Diabetes

(2011) S. A. Sarkar et al.   DIABETES

Serum CXCL1 concentrations are elevated in type 1 diabetes mellitus, possibly reflecting activity of anti-islet autoimmune activity

(2011) Kazuma Takahashi et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Treatment with Anakinra Improves Disposition Index But Not Insulin Sensitivity in Nondiabetic Subjects with the Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study

(2011) Edwin J. P. van Asseldonk et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hierarchies of NF-κB target-gene regulation

(2011) Stephen T Smale   NATURE IMMUNOLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Pancreatic β-Cell Death in Response to Pro-Inflammatory Cytokines Is Distinct from Genuine Apoptosis

(2011) J. Jason Collier et al.   PLoS One

Neutrophils cascading their way to inflammation

(2011) Christian D. Sadik et al.   TRENDS IN IMMUNOLOGY

Chemokines and chemokine receptors: new insights into cancer-related inflammation

(2010) Gwendal Lazennec et al.   TRENDS IN MOLECULAR MEDICINE

The IKK Complex, a Central Regulator of NF- B Activation

(2009) A. Israel   Cold Spring Harbor Perspectives in Biology

Autoimmune mechanisms in type 1 diabetes

(2008) Mikael Knip et al.   AUTOIMMUNITY REVIEWS

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Chemotaxis, chemokine receptors and human disease

(2008) Tian Jin et al.   CYTOKINE

Increased Expression of CCL2 in Insulin-Producing Cells of Transgenic Mice Promotes Mobilization of Myeloid Cells From the Bone Marrow, Marked Insulitis, and Diabetes

(2008) A. P. Martin et al.   DIABETES

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Chemokines and Their Receptors: Drug Targets in Immunity and Inflammation

(2007) Antonella Viola et al.   Annual Review of Pharmacology and Toxicology