标题
DEPTOR ubiquitination and destruction by SCFβ-TrCP
作者
关键词
-
出版物
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
Volume 303, Issue 2, Pages E163-E169
出版商
American Physiological Society
发表日期
2012-03-29
DOI
10.1152/ajpendo.00105.2012
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting the PI3K/Akt/mTOR Pathway – Beyond Rapalogs
- (2015) Oncotarget
- Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells
- (2012) Zheng Guo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- BMK1 Kinase Suppresses Epithelial-Mesenchymal Transition through the Akt/GSK3 Signaling Pathway
- (2012) R. Chen et al. CANCER RESEARCH
- mTOR complex 2 signaling and functions
- (2011) Won Jun Oh et al. CELL CYCLE
- The dynamic nature of autophagy in cancer
- (2011) A. C. Kimmelman GENES & DEVELOPMENT
- Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
- (2011) S. Alers et al. MOLECULAR AND CELLULAR BIOLOGY
- Interplay Between pVHL and mTORC1 Pathways in Clear-Cell Renal Cell Carcinoma
- (2011) B. Kucejova et al. MOLECULAR CANCER RESEARCH
- DEPTOR, an mTOR Inhibitor, Is a Physiological Substrate of SCFβTrCP E3 Ubiquitin Ligase and Regulates Survival and Autophagy
- (2011) Yongchao Zhao et al. MOLECULAR CELL
- mTOR Generates an Auto-Amplification Loop by Triggering the βTrCP- and CK1α-Dependent Degradation of DEPTOR
- (2011) Shanshan Duan et al. MOLECULAR CELL
- mTOR Drives Its Own Activation via SCFβTrCP-Dependent Degradation of the mTOR Inhibitor DEPTOR
- (2011) Daming Gao et al. MOLECULAR CELL
- Rapamycin passes the torch: a new generation of mTOR inhibitors
- (2011) Don Benjamin et al. NATURE REVIEWS DRUG DISCOVERY
- Control of mTORC1 signaling by the Opitz syndrome protein MID1
- (2011) E. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of mammalian target of rapamycin complex 1 (mTORC1) by hypoxia: causes and consequences
- (2011) Hakan Cam et al. Targeted Oncology
- Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase
- (2010) Hiroyuki Inuzuka et al. CANCER CELL
- mTORC1 signaling requires proteasomal function and the involvement of CUL4-DDB1 ubiquitin E3 ligase
- (2010) Papia Ghosh et al. CELL CYCLE
- Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway
- (2010) Kanako Kume et al. GENES TO CELLS
- Decreased Level of PDCD4 (Programmed Cell Death 4) Protein Activated Cell Proliferation in the Lung of A/J Mouse
- (2010) Soon-Kyung Hwang et al. Journal of Aerosol Medicine and Pulmonary Drug Delivery
- High expression levels of the mammalian target of rapamycin inhibitorDEPTORare predictive of response to thalidomide in myeloma
- (2010) Kevin D. Boyd et al. LEUKEMIA & LYMPHOMA
- Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase
- (2010) Mariam Aghajan et al. NATURE BIOTECHNOLOGY
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Role of CK1 in GSK3β-mediated phosphorylation and degradation of Snail
- (2010) Y Xu et al. ONCOGENE
- DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival
- (2009) Timothy R. Peterson et al. CELL
- Control of cell growth by the SCF and APC/C ubiquitin ligases
- (2009) Jeffrey R Skaar et al. CURRENT OPINION IN CELL BIOLOGY
- REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A–DDB1 ubiquitin ligase
- (2009) Samiksha Katiyar et al. EMBO REPORTS
- Glycolytic Flux Signals to mTOR through Glyceraldehyde-3-Phosphate Dehydrogenase-Mediated Regulation of Rheb
- (2009) M. N. Lee et al. MOLECULAR AND CELLULAR BIOLOGY
- Rapamycin induces transactivation of the EGFR and increases cell survival
- (2009) D Chaturvedi et al. ONCOGENE
- Ribosomal protein S6 kinase 1 interacts with and is ubiquitinated by ubiquitin ligase ROC1
- (2008) Ganna Panasyuk et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Pam (Protein associated with Myc) functions as an E3 Ubiquitin ligase and regulates TSC/mTOR signaling
- (2008) Sangyeul Han et al. CELLULAR SIGNALLING
- FBXW7 Targets mTOR for Degradation and Cooperates with PTEN in Tumor Suppression
- (2008) Jian-Hua Mao et al. SCIENCE
- The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
- (2008) Y. Sancak et al. SCIENCE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started