Rare functional variants in genome-wide association identified candidate genes for nonsyndromic clefts in the African population

Replication of Genome Wide Association Identified Candidate Genes Confirm the Role of Common and Rare Variants inPAX7andVAX1in the Etiology of Nonsyndromic CL(P)

(2013) Azeez Butali et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Resequencing ofVAX1in patients with nonsyndromic cleft lip with or without cleft palate

(2012) Entessar Nasser et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome-wide association on chromosome 1p22

(2012) Elizabeth J. Leslie et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Evaluating rare coding variants as contributing causes to non-syndromic cleft lip and palate

(2012) EJ Leslie et al.   CLINICAL GENETICS

Further evidence of association of theABCA4gene with cleft lip/palate

(2012) Clarissa Fontoura et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

(2012) Kerstin U Ludwig et al.   NATURE GENETICS

Why personalized medicine will fail if we stay the course

(2012) Edward Ramos et al.   Personalized Medicine

Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes

(2012) J. A. Tennessen et al.   SCIENCE

Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants

(2012) A. Keinan et al.   SCIENCE

The 8q24 Gene Desert: An Oasis of Non-Coding Transcriptional Activity

(2012) Konrad Huppi et al.   Frontiers in Genetics

Analysis of genomewide association signals for nonsyndromic cleft lip/palate in a Kenya African cohort

(2011) R. Christopher Weatherley-White et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Genetic Studies in the Nigerian Population Implicate an MSX1 Mutation in Complex Oral Facial Clefting Disorders

(2011) A. Butali et al.   CLEFT PALATE-CRANIOFACIAL JOURNAL

Cleft lip and palate: understanding genetic and environmental influences

(2011) Michael J. Dixon et al.   NATURE REVIEWS GENETICS

Genetic risk factors for nonsyndromic cleft lip with or without cleft palate in a Mesoamerican population: Evidence for IRF6 and variants at 8q24 and 10q25

(2010) Augusto Rojas-Martinez et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces

(2010) Hanka Venselaar et al.   BMC BIOINFORMATICS

Susceptibility locus for non-syndromic cleft lip with or without cleft palate on chromosome 10q25 confers risk in Estonian patients

(2010) Tiit Nikopensius et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4

(2010) Terri H Beaty et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

A Genome-Wide Association Study Identifies a Locus for Nonsyndromic Cleft Lip with or without Cleft Palate on 8q24

(2009) Struan F.A. Grant et al.   JOURNAL OF PEDIATRICS

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate

(2009) Elisabeth Mangold et al.   NATURE GENETICS

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24

(2009) Stefanie Birnbaum et al.   NATURE GENETICS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Human Splicing Finder: an online bioinformatics tool to predict splicing signals

(2009) François-Olivier Desmet et al.   NUCLEIC ACIDS RESEARCH

The impact of orofacial clefts on quality of life and healthcare use and costs

(2009) GL Wehby et al.   ORAL DISEASES