Why personalized medicine will fail if we stay the course

The success of pharmacogenomics in moving genetic association studies from bench to bedside: study design and implementation of precision medicine in the post-GWAS era

(2012) Marylyn D. Ritchie   HUMAN GENETICS

Tailoring Information Provision and Consent Processes to Research Contexts: The Value of Rapid Assessments

(2012) Susan Bull et al.   Journal of Empirical Research on Human Research Ethics

Common variants at 11p13 are associated with susceptibility to tuberculosis

(2012) Thorsten Thye et al.   NATURE GENETICS

HLA Class II Locus and Susceptibility to Podoconiosis

(2012) Fasil Tekola Ayele et al.   NEW ENGLAND JOURNAL OF MEDICINE

Application of the FST statistics to explore pharmacogenomic diversity in the Brazilian population

(2012) Guilherme Suarez-Kurtz et al.   PHARMACOGENOMICS

Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes

(2012) J. A. Tennessen et al.   SCIENCE

An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People

(2012) M. R. Nelson et al.   SCIENCE

Health disparities in the genomic era: the case for diversifying ethnic representation

(2012) Charles N Rotimi   Genome Medicine

Personalized Medicine: Progress and Promise

(2011) Isaac S. Chan et al.   Annual Review of Genomics and Human Genetics

A genome-wide association study of serum uric acid in African Americans

(2011) Bashira A Charles et al.   BMC Medical Genomics

Ethical Issues in Developing Pharmacogenetic Research Partnerships With American Indigenous Communities

(2011) B B Boyer et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

UGT1A1 is a major locus influencing bilirubin levels in African Americans

(2011) Guanjie Chen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Charting a course for genomic medicine from base pairs to bedside

(2011) Eric D. Green et al.   NATURE

Acute Mesenteric Infarction Associated with Atrial Fibrillation

(2011) Jia-Ming Wang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Translating pharmacogenomics into personalized medicine and drug development

(2011) Wei Zhang et al.   Personalized Medicine

Whole-genome resequencing in pharmacogenomics: moving away from past disparities to globally representative applications

(2011) Britt I Drögemöller et al.   PHARMACOGENOMICS

Genomic Ancestry, Self-Reported “Color” and Quantitative Measures of Skin Pigmentation in Brazilian Admixed Siblings

(2011) Tailce K. M. Leite et al.   PLoS One

Mapping of disease-associated variants in admixed populations

(2011) Daniel Shriner et al.   GENOME BIOLOGY

FTO Genetic Variation and Association With Obesity in West Africans and African Americans

(2010) A. Adeyemo et al.   DIABETES

Replication of genome-wide association studies (GWAS) loci for fasting plasma glucose in African-Americans

(2010) E. Ramos et al.   DIABETOLOGIA

Bridging the Divide between Genomic Science and Indigenous Peoples

(2010) Bette Jacobs et al.   JOURNAL OF LAW MEDICINE & ETHICS

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2

(2010) Thorsten Thye et al.   NATURE GENETICS

Genome-wide association studies in diverse populations

(2010) Noah A. Rosenberg et al.   NATURE REVIEWS GENETICS

Ancestry and Disease in the Age of Genomic Medicine

(2010) Charles N. Rotimi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomic Medicine — An Updated Primer

(2010) W. Gregory Feero et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacogenomics and adverse drug reactions

(2010) Shashi Amur et al.   Personalized Medicine

Interethnic comparisons of important pharmacology genes using SNP databases: potential application to drug regulatory assessments

(2010) Jieming Chen et al.   PHARMACOGENOMICS

Tailoring the process of informed consent in genetic and genomic research

(2010) Charles N Rotimi et al.   Genome Medicine

Impact of social stigma on the process of obtaining informed consent for genetic research on podoconiosis: a qualitative study

(2009) Fasil Tekola et al.   BMC Medical Ethics

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Genome-wide and fine-resolution association analysis of malaria in West Africa

(2009) Muminatou Jallow et al.   NATURE GENETICS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Variants Associated with Complex Human Diseases Show Wide Variation across Multiple Populations

(2009) A. Adeyemo et al.   Public Health Genomics

Next generation disparities in human genomics: concerns and remedies

(2009) Anna C. Need et al.   TRENDS IN GENETICS

A Genome-Wide Association Study of Hypertension and Blood Pressure in African Americans

(2009) Adebowale Adeyemo et al.   PLoS Genetics

Ethnogenetic layering (EL): an alternative to the traditional race model in human variation and health disparity studies

(2008) F. L. C. Jackson   ANNALS OF HUMAN BIOLOGY

Individual Genomes Instead of Race for Personalized Medicine

(2008) PC Ng et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Currents in Contemporary Ethics for Asians Only? The Perils of Ancestry-Based Drug Prescribing

(2008) Perry W. Payne   JOURNAL OF LAW MEDICINE & ETHICS

Casting a wider net for diabetes susceptibility genes

(2008) Mark I McCarthy   NATURE GENETICS