Antiepileptic drugs and pregnancy outcomes

Use of Antiepileptic Medications in Pregnancy in Relation to Risks of Birth Defects

(2011) Martha M. Werler et al.   ANNALS OF EPIDEMIOLOGY

Antiepileptic drugs interact with folate and vitamin B12 serum levels

(2011) Michael Linnebank et al.   ANNALS OF NEUROLOGY

The Teratogenic Potencies of Valproic Acid Derivatives and Their Effects on Biological End-points are Related to Changes in Histone Deacetylase and Erk1/2 Activities

(2011) Kamil Gotfryd et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Foetal antiepileptic drug exposure and verbal versus non-verbal abilities at three years of age

(2011) Kimford J. Meador et al.   BRAIN

Effect of Valproate, Lamotrigine and Levetiracetam on Excitability and Firing Properties of CA1 Neurons in Rat Brain Slices

(2011) Marita Englund et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Teratogenicity of the newer antiepileptic drugs – the Australian experience

(2011) F.J.E. Vajda et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry

(2011) Torbjörn Tomson et al.   LANCET NEUROLOGY

Language skills of school-aged children prenatally exposed to antiepileptic drugs

(2011) C. Nadebaum et al.   NEUROLOGY

Child development following in utero exposure: Levetiracetam vs sodium valproate

(2011) R. Shallcross et al.   NEUROLOGY

Gabapentin promotes inhibition by enhancing hyperpolarization-activated cation currents and spontaneous firing in hippocampal CA1 interneurons

(2011) Bi-Wen Peng et al.   NEUROSCIENCE LETTERS

The Embryonic Stem Cell Test as Tool to Assess Structure-Dependent Teratogenicity: The Case of Valproic Acid

(2011) Christian Riebeling et al.   TOXICOLOGICAL SCIENCES

Multiple point action mechanism of valproic acid-teratogenicity alleviated by folic acid, vitamin C, And N-acetylcysteine in chicken embryo model

(2011) Chiu-Lan Hsieh et al.   TOXICOLOGY

Effect of pregnancy on topiramate pharmacokinetics in rabbits

(2011) Kamal M. Matar et al.   XENOBIOTICA

Intrauterine growth restriction and skeletal variations in mouse fetuses induced by vigabatrin administered at preimplantation stages of development

(2010) Rengasamy Padmanabhan et al.   CONGENITAL ANOMALIES

Update on Anticonvulsant Drugs

(2010) Derek J. Chong et al.   Current Neurology and Neuroscience Reports

Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid

(2010) Neta Pessah et al.   EPILEPSIA

Teratogenic effects of antiepileptic drugs

(2010) Denise S Hill et al.   Expert Review of Neurotherapeutics

Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid

(2010) Dan Kaufmann et al.   NEUROPHARMACOLOGY

Does folic acid use decrease the risk for spina bifida after in utero exposure to valproic acid?

(2010) Janneke Jentink et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Vigabatrin (VGB) administered during late gestation lowers maternal folate concentration and causes pregnancy loss, fetal growth restriction and skeletal hypoplasia in the mouse☆

(2010) R. Padmanabhan et al.   REPRODUCTIVE TOXICOLOGY

Is lamotrigine a significant human teratogen? Observations from the Australian Pregnancy Register

(2010) F.J.E. Vajda et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Cognitive abilities and behaviour of children exposed to antiepileptic drugs in utero

(2009) Rebecca L Bromley et al.   CURRENT OPINION IN NEUROLOGY

Managing antiepileptic drugs during pregnancy and lactation

(2009) Anne Sabers et al.   CURRENT OPINION IN NEUROLOGY

Teratogenic effects of carbamazepine on embryonic eye development in pregnant mice

(2009) Mohammad Afshar et al.   Cutaneous and Ocular Toxicology

Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes

(2009) Cynthia L. Harden et al.   EPILEPSIA

A prospective study of cognitive fluency and originality in children exposed in utero to carbamazepine, lamotrigine, or valproate monotherapy

(2009) Kelly M. McVearry et al.   EPILEPSY & BEHAVIOR

Antiepileptic drug use in women of childbearing age

(2009) Kimford J. Meador et al.   EPILEPSY & BEHAVIOR

Pharmacokinetics of topiramate during pregnancy

(2009) Inger Öhman et al.   EPILEPSY RESEARCH

Teratogenic Effects of Antiepileptic Medications

(2009) Torbjörn Tomson et al.   NEUROLOGIC CLINICS

INCREASED FREQUENCY OF ISOLATED CLEFT PALATE IN INFANTS EXPOSED TO LAMOTRIGINE DURING PREGNANCY

(2009) S. J. Hunt et al.   NEUROLOGY

Cognitive Function at 3 Years of Age after Fetal Exposure to Antiepileptic Drugs

(2009) Kimford J. Meador et al.   NEW ENGLAND JOURNAL OF MEDICINE

Valproic acid in pregnancy: How much are we endangering the embryo and fetus?

(2009) Asher Ornoy   REPRODUCTIVE TOXICOLOGY

Pregnancy with epilepsy: Obstetric and neonatal outcome of a controlled study

(2009) G. Mawer et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Determination of human teratogenicity by the astute clinician method: Review of illustrative agents and a proposal of guidelines

(2008) John C. Carey et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Pregnancy Outcome after In Utero Exposure to Valproate

(2008) Orna Diav-Citrin et al.   CNS DRUGS

Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: A potential for a second generation drug to valproic acid

(2008) Jakob Avi Shimshoni et al.   EPILEPSIA

In utero exposure to vigabatrin: No indication of visual field loss

(2008) Charlotte Lawthom et al.   EPILEPSIA

Motor and mental development of infants exposed to antiepileptic drugs in utero

(2008) Sanjeev V. Thomas et al.   EPILEPSY & BEHAVIOR

The behavioral consequences of exposure to antiepileptic drugs in utero

(2008) J. Vinten et al.   EPILEPSY & BEHAVIOR

Antiepileptic drugs and brain maturation: Fetal exposure to lamotrigine generates cortical malformations in rats

(2008) Jean-Bernard Manent et al.   EPILEPSY RESEARCH

Pregnancy outcomes in women with epilepsy: A systematic review and meta-analysis of published pregnancy registries and cohorts

(2008) Kimford Meador et al.   EPILEPSY RESEARCH

Spontaneous abortion and the prophylactic effect of folic acid supplementation in epileptic women undergoing antiepileptic therapy

(2008) S. Pittschieler et al.   JOURNAL OF NEUROLOGY

Folic acid use and major congenital malformations in offspring of women with epilepsy: a prospective study from the UK Epilepsy and Pregnancy Register

(2008) J I Morrow et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Topiramate in pregnancy: Preliminary experience from the UK Epilepsy and Pregnancy Register

(2008) S. Hunt et al.   NEUROLOGY

Pregnancy registries in epilepsy: A consensus statement on health outcomes

(2008) K. J. Meador et al.   NEUROLOGY

Increased frequency of isolated cleft palate in infants exposed to lamotrigine during pregnancy

(2008) L. B. Holmes et al.   NEUROLOGY

Cardiac Malformations Are Increased in Infants of Mothers with Epilepsy

(2008) S. V. Thomas et al.   PEDIATRIC CARDIOLOGY

The outcome of pregnancy following topiramate treatment: A study on 52 pregnancies

(2008) A ORNOY et al.   REPRODUCTIVE TOXICOLOGY