Review
Cell Biology
Alissa Trzeciak, Ya-Ting Wang, Justin Shaun Arnold Perry
Summary: Clearance of apoptotic cells, known as efferocytosis, is essential for processes like embryonic development and immune cell development. This process poses intriguing cell metabolism problems where phagocytes like macrophages play a crucial role.
Review
Endocrinology & Metabolism
Beatriz Rodrigues Risuenho Peinado, Deborah Ribeiro Frazao, Leonardo Oliveira Bittencourt, Renata Duarte de Souza-Rodrigues, Maria Tereza Campos Vidigal, Douglas Teixeira da Silva, Luiz Renato Paranhos, Marcela Barauna Magno, Nathalia Carolina Fernandes Fagundes, Lucianne Cople Maia, Rafael Rodrigues Lima
Summary: Obesity is a growing public health problem and food consumption decisions, influenced by taste perceptions, play an important role. A systematic review found an association between obesity and taste alterations, indicating the need for further research to confirm this hypothesis using more sensitive methods.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Endocrinology & Metabolism
Rebecca L. Pearl, Thomas A. Wadden, John M. Jakicic
Summary: The relationship between weight stigma and physical activity is complex, with most studies finding that everyday weight discrimination and internalization are associated with reduced physical activity, and weight-based teasing in youth is also linked to reduced physical activity. The associations are inconsistent and often indirect, suggesting the need for further investigation in future research with larger samples and longitudinal assessments.
Review
Gastroenterology & Hepatology
Thergiory Irrazabal, Bhupesh K. Thakur, Kenneth Croitoru, Alberto Martin
Summary: Patients with inflammatory bowel disease have increased oxidative damage, potentially leading to colon cancer, while exogenous antioxidant molecules can reduce intestinal oxidation and prevent these cancers from developing.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Review
Endocrinology & Metabolism
Leonardo de Andrade Mesquita, Giovana Fagundes Piccoli, Gabriella Richter da Natividade, Bernardo Frison Spiazzi, Veronica Colpani, Fernando Gerchman
Summary: This study analyzed the association between lorcaserin and cancer risk, suggesting that current evidence does not confirm an increased risk of cancer with lorcaserin, but indicates a trend in this direction.
Review
Nutrition & Dietetics
Maninder Kaur Ahluwalia
Summary: Obesity is a chronic health problem that is associated with numerous comorbidities. Its global prevalence has tripled over the past five decades and poses a serious threat to society and future generations. Diet plays a key role in the development of obesity, and the timing of meals is increasingly recognized as essential for human metabolism.
Review
Oncology
Yi Lu, Yutao Wang, Hao Su, Hongjun Li
Summary: This meta-analysis investigated the role of PD-L1 in the survival outcomes of penile cancer patients. It revealed that higher PD-L1 expression on tumor cells was associated with shorter cancer-specific survival. However, no associations were found between PD-L1 expression and overall survival. Furthermore, PD-L1 expression was related to tumor stage, tumor grade, lymph node status, and HPV status.
FRONTIERS IN ONCOLOGY
(2022)
Review
Oncology
Ashley Kim, Karen C. Chung, Christopher Keir, Donald L. Patrick
Summary: This study evaluated the psychosocial impact of cancer screening and found that it is generally low overall and short-lived. Some individuals may experience anxiety and distress during the screening process, especially those with a higher risk of cancer.
Review
Medicine, General & Internal
Kim Devon Terga Le, Marcos Fabio DosSantos, Parisa Gazerani
Summary: Burning mouth syndrome (BMS) is a persistent intraoral burning sensation, commonly experienced by postmenopausal women. This systematic review found a higher prevalence of extraoral dryness in BMS patients, suggesting a potential central mechanism.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Behavioral Sciences
Zainab Alimoradi, Nilofar Rajabi Majd, Anders Brostrom, Hector W. H. Tsang, Parmveer Singh, Maurice M. Ohayon, Chung-Ying Lin, Amir H. Pakpour
Summary: This systematic review and meta-analysis found a significant association between alexithymia and sleep problems, especially among people with any medical condition.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Review
Medicine, General & Internal
Yue Chen, Xingyu Cheng, Chenyu Sun, Na Hyun Kim, Sujatha Kailas, Faisal Qureshi, Zeid Karadsheh, Yile Wu, Lei Hu, Zhen Zhou, Chandur Bhan, Keun Young Kim, Raveena Manem, Ce Cheng, Qin Zhou
Summary: A meta-analysis was conducted to reassess the effects of metformin on esophageal cancer, and the results showed that metformin use was associated with a reduced risk of esophageal cancer. More well-designed studies are still needed to further elaborate on these associations.
POSTGRADUATE MEDICAL JOURNAL
(2022)
Review
Biochemistry & Molecular Biology
Bi-jun Wang, Jun-yi Chen, Yu Guan, Da-chao Liu, Zi-chuan Cao, Jin Kong, Zheng-Sheng Wu, Wen-Yong Wu
Summary: The meta-analysis conducted in this study found no significant association between P2RX7 rs3751143 polymorphism and the risk of cancer across different models.
BIOSCIENCE REPORTS
(2021)
Review
Multidisciplinary Sciences
Waruna L. Peiris, Flavia M. Cicuttini, Sultana Monira Hussain, Mahnuma M. Estee, Lorena Romero, Tom A. Ranger, Jessica L. Fairley, Emily C. McLean, Donna M. Urquhart
Summary: This systematic review found evidence of a relationship between body fat and its central distribution with low back and knee pain, as well as a longitudinal relationship between adiposity and back, knee and foot pain. These results highlight the potential for developing novel treatments at these sites.
Review
Chemistry, Analytical
Omer Dilian, Ron Kimmel, Roy Tezmah-Shahar, Maayan Agmon
Summary: This review evaluated the potential of photogrammetry in quantifying age-related postural changes. After reviewing and analyzing the studies, significant changes were found in thoracic kyphosis, lumbar lordosis, and sagittal inclination with aging. However, the existing studies had methodological difficulties and further research with validated photogrammetrical methods and improved methodologies is needed.
Review
Food Science & Technology
Yue Li, Mingjun Sun
Summary: The meta-analysis found no association between cholesterol consumption and colorectal cancer in cohort studies when comparing high vs low intake categories and assessing dose-response relationship. However, significant associations were found in case-control studies. Additional prospective cohort studies are needed to confirm these findings.
JOURNAL OF FUNCTIONAL FOODS
(2021)