Antitumor activity of an anti-CD98 antibody

Discovery of Fully Human Anti-MET Monoclonal Antibodies with Antitumor Activity against Colon Cancer Tumor Models In Vivo

(2015) Edward Htun van der Horst et al.   NEOPLASIA

Monoclonal antibody binding-site diversity assessment with a cell-based clustering assay

(2014) Sindy Liao-Chan et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Rituximab causes a polarization of B cells that augments its therapeutic function in NK-cell-mediated antibody-dependent cellular cytotoxicity

(2013) D. Rudnicka et al.   BLOOD

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia

(2013) L. Willems et al.   BLOOD

Antibody Therapeutics in Cancer

(2013) M. X. Sliwkowski et al.   SCIENCE

CD98 at the crossroads of adaptive immunity and cancer

(2012) J. M. Cantor et al.   JOURNAL OF CELL SCIENCE

Development and validation of an antibody-dependent cell-mediated cytotoxicity-reporter gene assay

(2012) Bhavin S. Parekh et al.   mAbs

Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies

(2011) W. Alduaij et al.   BLOOD

An Fcγ Receptor-Dependent Mechanism Drives Antibody-Mediated Target-Receptor Signaling in Cancer Cells

(2011) Nicholas S. Wilson et al.   CANCER CELL

How were new medicines discovered?

(2011) David C. Swinney et al.   NATURE REVIEWS DRUG DISCOVERY

Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: A possible target for combination therapy with anti-proliferative aminopeptidase inhibitors

(2010) Xuetao Fan et al.   BIOCHEMICAL PHARMACOLOGY

Inhibition of L-Type Amino Acid Transporter Modulates the Expression of Cell Cycle Regulatory Factors in KB Oral Cancer Cells

(2010) Chun Sung Kim et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

l-Type amino acid transporter 1 inhibitors inhibit tumor cell growth

(2009) Koji Oda et al.   CANCER SCIENCE

Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy

(2009) Paul Nicklin et al.   CELL

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE