Review article: drug-induced liver injury - its pathophysiology and evolving diagnostic tools

Plasma MicroRNA-122 as a Biomarker for Viral-, Alcohol-, and Chemical-Related Hepatic Diseases

(2010) Y. Zhang et al.   CLINICAL CHEMISTRY

The Application of Metabonomics to Predict Drug-Induced Liver Injury

(2010) T M O'Connell et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans

(2010) J H Winnike et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans

(2010) Guo-Kun Wang et al.   EUROPEAN HEART JOURNAL

Pharmacogenetics of drug-induced liver injury

(2010) Stefan Russmann et al.   HEPATOLOGY

Quantitative analyses and transcriptomic profiling of circulating messenger RNAs as biomarkers of rat liver injury

(2010) Barbara A. Wetmore et al.   HEPATOLOGY

Human leucocyte antigen class II genotype in susceptibility and resistance to co-amoxiclav-induced liver injury

(2010) Peter T. Donaldson et al.   JOURNAL OF HEPATOLOGY

Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells

(2010) Anke Van Summeren et al.   TOXICOLOGICAL SCIENCES

Aryl Hydrocarbon Receptor Nuclear Translocator in Hepatocytes Is Required for Aryl Hydrocarbon Receptor–Mediated Adaptive and Toxic Responses in Liver

(2010) Manabu Nukaya et al.   TOXICOLOGICAL SCIENCES

The discovery and development of proteomic safety biomarkers for the detection of drug-induced liver toxicity

(2010) David E. Amacher   TOXICOLOGY AND APPLIED PHARMACOLOGY

A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran

(2009) Ulf Andersson et al.   BIOMARKERS

Current Concepts of Mechanisms in Drug-Induced Hepatotoxicity

(2009) Stefan Russmann et al.   CURRENT MEDICINAL CHEMISTRY

Drug-Induced Liver Injury Network (DILIN) Prospective Study

(2009) Robert J. Fontana et al.   DRUG SAFETY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Circulating microRNAs, potential biomarkers for drug-induced liver injury

(2009) K. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

(2009) T. A. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Association Studies in Drug-Induced Liver Injury

(2009) Ann Daly et al.   SEMINARS IN LIVER DISEASE

Biochemical mechanisms in drug-induced liver injury: Certainties and doubts

(2009) Ignazio Grattagliano et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

(2008) Xi Chen et al.   CELL RESEARCH

Cellular and Molecular Mechanisms of Liver Injury

(2008) Harmeet Malhi et al.   GASTROENTEROLOGY

HLA-B*5701 Screening for Hypersensitivity to Abacavir

(2008) Simon Mallal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acquired Resistance to Acetaminophen Hepatotoxicity is Associated with Induction of Multidrug Resistance-Associated Protein 4 (Mrp4) in Proliferating Hepatocytes

(2008) Lauren M. Aleksunes et al.   TOXICOLOGICAL SCIENCES