The Application of Metabonomics to Predict Drug-Induced Liver Injury

Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans

(2010) J H Winnike et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

An Integrative Approach for Identifying a Metabolic Phenotype Predictive of Individualized Pharmacokinetics of Tacrolimus

(2010) P B Phapale et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran

(2009) Ulf Andersson et al.   BIOMARKERS

Monitoring for Hepatotoxicity: What Is the Predictive Value of Liver “Function” Tests?

(2009) JR Senior   CLINICAL PHARMACOLOGY & THERAPEUTICS

Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation

(2009) Rick D. Fannin et al.   HEPATOLOGY

Individual Human Phenotypes in Metabolic Space and Time

(2009) Patrizia Bernini et al.   JOURNAL OF PROTEOME RESEARCH

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

(2009) T. A. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomarkers for the Diagnosis and Management of Drug-Induced Liver Injury

(2009) Paul Watkins   SEMINARS IN LIVER DISEASE

Using controlled clinical trials to learn more about acute drug-induced liver injury

(2008) Paul B. Watkins et al.   HEPATOLOGY

Human metabolic phenotype diversity and its association with diet and blood pressure

(2008) Elaine Holmes et al.   NATURE

HLA-B*5701 Screening for Hypersensitivity to Abacavir

(2008) Simon Mallal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evidence of different metabolic phenotypes in humans

(2008) M. Assfalg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA