HIV cure and eradication: how will we get from the laboratory to effective clinical trials?
出版年份 2011 全文链接
标题
HIV cure and eradication: how will we get from the laboratory to effective clinical trials?
作者
关键词
-
出版物
AIDS
Volume 25, Issue 7, Pages 885-897
出版商
Ovid Technologies (Wolters Kluwer Health)
发表日期
2011-03-17
DOI
10.1097/qad.0b013e3283467041
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Curing HIV: Pharmacologic Approaches to Target HIV-1 Latency
- (2011) Shailesh K. Choudhary et al. Annual Review of Pharmacology and Toxicology
- Elite Suppressors Harbor Low Levels of Integrated HIV DNA and High Levels of 2-LTR Circular HIV DNA Compared to HIV+ Patients On and Off HAART
- (2011) Erin H. Graf et al. PLoS Pathogens
- Episomal Viral cDNAs Identify a Reservoir That Fuels Viral Rebound after Treatment Interruption and That Contributes to Treatment Failure
- (2011) Mark Sharkey et al. PLoS Pathogens
- Risk of all-cause mortality associated with nonfatal AIDS and serious non-AIDS events among adults infected with HIV
- (2010) Jacqueline Neuhaus et al. AIDS
- Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy
- (2010) Steven A Yukl et al. AIDS
- Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection
- (2010) Laurent Hocqueloux et al. AIDS
- Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication
- (2010) Tae-Wook Chun et al. AIDS
- HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy
- (2010) Hiromi Imamichi et al. AIDS
- Short‐Course Raltegravir Intensification Does Not Reduce Persistent Low‐Level Viremia in Patients with HIV‐1 Suppression during Receipt of Combination Antiretroviral Therapy
- (2010) D. McMahon et al. CLINICAL INFECTIOUS DISEASES
- Infrequent Recovery of HIV from but Robust Exogenous Infection of Activated CD4+T Cells in HIV Elite Controllers
- (2010) B. Julg et al. CLINICAL INFECTIOUS DISEASES
- Reduced Replication Capacity of NL4-3 Recombinant Viruses Encoding Reverse Transcriptase–Integrase Sequences From HIV-1 Elite Controllers
- (2010) Zabrina L Brumme et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Despite being highly diverse, immunovirological status strongly correlates with clinical symptoms during primary HIV-1 infection: a cross-sectional study based on 674 patients enrolled in the ANRS CO 06 PRIMO cohort
- (2010) J. Ghosn et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Differences in HIV Burden and Immune Activation within the Gut of HIV‐Positive Patients Receiving Suppressive Antiretroviral Therapy
- (2010) Steven A. Yukl et al. JOURNAL OF INFECTIOUS DISEASES
- Both CD31+and CD31−Naive CD4+T Cells Are Persistent HIV Type 1–Infected Reservoirs in Individuals Receiving Antiretroviral Therapy
- (2010) Fiona Wightman et al. JOURNAL OF INFECTIOUS DISEASES
- Markers of Inflammation, Coagulation, and Renal Function Are Elevated in Adults with HIV Infection
- (2010) Jacqueline Neuhaus et al. JOURNAL OF INFECTIOUS DISEASES
- Leukocyte Immunoglobulin-Like Receptors Maintain Unique Antigen-Presenting Properties of Circulating Myeloid Dendritic Cells in HIV-1-Infected Elite Controllers
- (2010) J. Huang et al. JOURNAL OF VIROLOGY
- Immunodominant HIV-Specific CD8+ T-Cell Responses Are Common to Blood and Gastrointestinal Mucosa, and Gag-Specific Responses Dominate in Rectal Mucosa of HIV Controllers
- (2010) A. L. Ferre et al. JOURNAL OF VIROLOGY
- Interleukin-21-Producing HIV-1-Specific CD8 T Cells Are Preferentially Seen in Elite Controllers
- (2010) L. D. Williams et al. JOURNAL OF VIROLOGY
- Combinatorial Latency Reactivation for HIV-1 Subtypes and Variants
- (2010) J. C. Burnett et al. JOURNAL OF VIROLOGY
- Impaired Replication Capacity of Acute/Early Viruses in Persons Who Become HIV Controllers
- (2010) T. Miura et al. JOURNAL OF VIROLOGY
- Control of HIV-1 in Elite Suppressors despite Ongoing Replication and Evolution in Plasma Virus
- (2010) K. A. O'Connell et al. JOURNAL OF VIROLOGY
- Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo
- (2010) Nathalia Holt et al. NATURE BIOTECHNOLOGY
- HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs
- (2010) Christoph C Carter et al. NATURE MEDICINE
- HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects
- (2010) Maria J Buzón et al. NATURE MEDICINE
- Systemic Administration of Antiretrovirals Prior to Exposure Prevents Rectal and Intravenous HIV-1 Transmission in Humanized BLT Mice
- (2010) Paul W. Denton et al. PLoS One
- Viral Decay Kinetics in the Highly Active Antiretroviral Therapy-Treated Rhesus Macaque Model of AIDS
- (2010) Jesse D. Deere et al. PLoS One
- A Tonsillar PolyICLC/AT-2 SIV Therapeutic Vaccine Maintains Low Viremia Following Antiretroviral Therapy Cessation
- (2010) Panagiotis Vagenas et al. PLoS One
- Profound Depletion of HIV-1 Transcription in Patients Initiating Antiretroviral Therapy during Acute Infection
- (2010) Adrian Schmid et al. PLoS One
- Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion
- (2010) Olivier Bourry et al. Retrovirology
- HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals
- (2010) D. Trono et al. SCIENCE
- RNA-Based Gene Therapy for HIV with Lentiviral Vector-Modified CD34+ Cells in Patients Undergoing Transplantation for AIDS-Related Lymphoma
- (2010) D. L. DiGiusto et al. Science Translational Medicine
- Patients on HAART often have an excess of unintegrated HIV DNA: Implications for monitoring reservoirs
- (2010) Luis M. Agosto et al. VIROLOGY
- Cell line-dependent variability in HIV activation employing DNMT inhibitors
- (2010) Guerau Fernandez et al. Virology Journal
- Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control
- (2010) Adam R. Hersperger et al. PLoS Pathogens
- Prolonged valproic acid treatment does not reduce the size of latent HIV reservoir
- (2009) Nathalie Sagot-Lerolle et al. AIDS
- Greater viral rebound and reduced time to resume antiretroviral therapy after therapeutic immunization with the ALVAC-HIV vaccine (vCP1452)
- (2009) Brigitte Autran et al. AIDS
- Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors
- (2009) Nancie M Archin et al. AIDS
- The novel histone deacetylase inhibitors metacept-1 and metacept-3 potently increase HIV-1 transcription in latently infected cells
- (2009) Miranda Shehu-Xhilaga et al. AIDS
- Persistent HIV RNA shedding in semen despite effective antiretroviral therapy
- (2009) Prameet M Sheth et al. AIDS
- Expression of Latent HIV Induced by the Potent HDAC Inhibitor Suberoylanilide Hydroxamic Acid
- (2009) Nancie M. Archin et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection
- (2009) I. Sereti et al. BLOOD
- An HDAC inhibitor enhances the antitumor activity of a CMV promoter-driven DNA vaccine
- (2009) M-D Lai et al. CANCER GENE THERAPY
- Clinical Studies of Histone Deacetylase Inhibitors
- (2009) H. M. Prince et al. CLINICAL CANCER RESEARCH
- Corneal Stromal Bed Quality Obtained With Mechanical Microkeratome and Femtosecond Laser
- (2009) Sathish Srinivasan et al. CORNEA
- Reactivation of DNA viruses in association with histone deacetylase inhibitor therapy: a case series report
- (2009) D. Ritchie et al. HAEMATOLOGICA
- Suberoylanilide Hydroxamic Acid Reactivates HIV from Latently Infected Cells
- (2009) Xavier Contreras et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Heterogeneity in HIV Suppression by CD8 T Cells from HIV Controllers: Association with Gag-Specific CD8 T Cell Responses
- (2009) A. Saez-Cirion et al. JOURNAL OF IMMUNOLOGY
- Persistent Low‐Level Viremia in HIV‐1 Elite Controllers and Relationship to Immunologic Parameters
- (2009) Florencia Pereyra et al. JOURNAL OF INFECTIOUS DISEASES
- No Evidence for Decay of the Latent Reservoir in HIV‐1–Infected Patients Receiving Intensive Enfuvirtide‐Containing Antiretroviral Therapy
- (2009) Rajesh T. Gandhi et al. JOURNAL OF INFECTIOUS DISEASES
- Human Immunodeficiency Virus Integrates Directly into Naive Resting CD4+ T Cells but Enters Naive Cells Less Efficiently than Memory Cells
- (2009) J. Dai et al. JOURNAL OF VIROLOGY
- Viral Sanctuaries during Highly Active Antiretroviral Therapy in a Nonhuman Primate Model for AIDS
- (2009) T. W. North et al. JOURNAL OF VIROLOGY
- Analysis of Human Immunodeficiency Virus Type 1 Viremia and Provirus in Resting CD4+ T Cells Reveals a Novel Source of Residual Viremia in Patients on Antiretroviral Therapy
- (2009) T. P. Brennan et al. JOURNAL OF VIROLOGY
- HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
- (2009) Nicolas Chomont et al. NATURE MEDICINE
- Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs
- (2009) Mayte Coiras et al. NATURE REVIEWS MICROBIOLOGY
- Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation
- (2009) Gero Hütter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Synergistic Activation of HIV-1 Expression by Deacetylase Inhibitors and Prostratin: Implications for Treatment of Latent Infection
- (2009) Sophie Reuse et al. PLoS One
- Cellular Levels of HIV Unspliced RNA from Patients on Combination Antiretroviral Therapy with Undetectable Plasma Viremia Predict the Therapy Outcome
- (2009) Alexander O. Pasternak et al. PLoS One
- Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy
- (2009) J. B. Dinoso et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Challenge of Finding a Cure for HIV Infection
- (2009) D. D. Richman et al. SCIENCE
- Modeling Latently Infected Cell Activation: Viral and Latent Reservoir Persistence, and Viral Blips in HIV-infected Patients on Potent Therapy
- (2009) Libin Rong et al. PLoS Computational Biology
- CpG Methylation Controls Reactivation of HIV from Latency
- (2009) Jana Blazkova et al. PLoS Pathogens
- Novel humanized murine models for HIV research
- (2009) Paul W. Denton et al. Current HIV/AIDS Reports
- Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells
- (2008) Nancy M Archin et al. AIDS
- HIV-DNA in rectal cells is well correlated with HIV-DNA in blood in different groups of patients, including long-term non-progressors
- (2008) Véronique Avettand-Fenoel et al. AIDS
- Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control
- (2008) A. L. Ferre et al. BLOOD
- Histone Deacetylase Inhibitor Panobinostat Induces Clinical Responses with Associated Alterations in Gene Expression Profiles in Cutaneous T-Cell Lymphoma
- (2008) L. Ellis et al. CLINICAL CANCER RESEARCH
- Early Control of HIV-1 Infection in Long-Term Nonprogressors Followed Since Diagnosis in the ANRS SEROCO/HEMOCO Cohort
- (2008) Yoann Madec et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Persistence of HIV in Gut‐Associated Lymphoid Tissue despite Long‐Term Antiretroviral Therapy
- (2008) Tae‐Wook Chun et al. JOURNAL OF INFECTIOUS DISEASES
- Dynamics of Total, Linear Nonintegrated, and Integrated HIV‐1 DNA In Vivo and In Vitro
- (2008) Kersten K. Koelsch et al. JOURNAL OF INFECTIOUS DISEASES
- LTR real-time PCR for HIV-1 DNA quantitation in blood cells for early diagnosis in infants born to seropositive mothers treated in HAART area (ANRS CO 01)
- (2008) Avettand-Fènoël Véronique et al. JOURNAL OF MEDICAL VIROLOGY
- HLA-Associated Alterations in Replication Capacity of Chimeric NL4-3 Viruses Carrying gag-protease from Elite Controllers of Human Immunodeficiency Virus Type 1
- (2008) T. Miura et al. JOURNAL OF VIROLOGY
- Evidence for Persistent Low-Level Viremia in Individuals Who Control Human Immunodeficiency Virus in the Absence of Antiretroviral Therapy
- (2008) H. Hatano et al. JOURNAL OF VIROLOGY
- Distinct Genetic Loci Control Plasma HIV-RNA and Cellular HIV-DNA Levels in HIV-1 Infection: The ANRS Genome Wide Association 01 Study
- (2008) Cyril Dalmasso et al. PLoS One
- Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy
- (2008) S. Palmer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Relationship between T Cell Activation and CD4+T Cell Count in HIV‐Seropositive Individuals with Undetectable Plasma HIV RNA Levels in the Absence of Therapy
- (2007) Peter W. Hunt et al. JOURNAL OF INFECTIOUS DISEASES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now