Age-associated impaired plasmacytoid dendritic cell functions lead to decreased CD4 and CD8 T cell immunity

An Important Role for Type III Interferon (IFN- /IL-28) in TLR-Induced Antiviral Activity

(2014) N. Ank et al.   JOURNAL OF IMMUNOLOGY

Aging Impairs IFN Regulatory Factor 7 Up-Regulation in Plasmacytoid Dendritic Cells during TLR9 Activation

(2014) H. W. Stout-Delgado et al.   JOURNAL OF IMMUNOLOGY

Influenza-Induced Production of Interferon-Alpha is Defective in Geriatric Individuals

(2010) David H. Canaday et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response

(2010) Alexander Panda et al.   JOURNAL OF IMMUNOLOGY

Lambda Interferon Renders Epithelial Cells of the Respiratory and Gastrointestinal Tracts Resistant to Viral Infections

(2010) M. Mordstein et al.   JOURNAL OF VIROLOGY

Expression of Type III Interferon (IFN) in the Vaginal Mucosa Is Mediated Primarily by Dendritic Cells and Displays Stronger Dependence on NF- B than Type I IFNs

(2010) M. B. Iversen et al.   JOURNAL OF VIROLOGY

Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells

(2009) M. R. Khaitov et al.   ALLERGY

The lack of protective immunity against RSV in the elderly

(2009) O. SCHILDGEN   EPIDEMIOLOGY AND INFECTION

Despite IFN-λ receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines

(2009) K Witte et al.   GENES AND IMMUNITY

Aging is associated with a numerical and functional decline in plasmacytoid dendritic cells, whereas myeloid dendritic cells are relatively unaltered in human peripheral blood

(2009) Yu Jing et al.   HUMAN IMMUNOLOGY

Interferon-λs: the modulators of antivirus, antitumor, and immune responses

(2009) Mingcai Li et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Limited expansion of virus-specific CD8 T cells in the aged environment

(2009) Jiu Jiang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Antiviral activity of type I interferons and interleukins 29 and 28a (type III interferons) against Apeu virus

(2008) G ALMEIDA et al.   ANTIVIRAL RESEARCH

PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon

(2008) H. Watarai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

(2008) Caroline Sommereyns et al.   PLoS Pathogens