Despite IFN-λ receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines

An Important Role for Type III Interferon (IFN- /IL-28) in TLR-Induced Antiviral Activity

(2014) N. Ank et al.   JOURNAL OF IMMUNOLOGY

IFN-α and IFN-λ differ in their antiproliferative effects and duration of JAK/STAT signaling activity

(2010) Stephen G. Maher et al.   CANCER BIOLOGY & THERAPY

IFN- 1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells

(2009) J. Dai et al.   BLOOD

Interferon-λ Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family

(2009) Hans Henrik Gad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type III and I Interferons Increase HIV Uptake and Replication in Human Cells That Overexpress CD4, CCR5, and CXCR4

(2008) Caterina Serra et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Interferon-β treatment for relapsing multiple sclerosis

(2008) Bianca Weinstock-Guttman et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Human interferon-λ3 is a potent member of the type III interferon family

(2008) C Dellgren et al.   GENES AND IMMUNITY

Interferon-λ1 (interleukin-29) preferentially down-regulates interleukin-13 over other T helper type 2 cytokine responsesin vitro

(2008) Shekar Srinivas et al.   IMMUNOLOGY

The Stability of the Ternary Interferon-Receptor Complex Rather than the Affinity to the Individual Subunits Dictates Differential Biological Activities

(2008) Eyal Kalie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Next Generation of Immunotherapy for Melanoma

(2008) John M. Kirkwood et al.   JOURNAL OF CLINICAL ONCOLOGY

Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes

(2008) Kerstin Wolk et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

(2008) Markus Mordstein et al.   PLoS Pathogens

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

(2008) Caroline Sommereyns et al.   PLoS Pathogens