Cobalt(II)-Catalyzed Isocyanide Insertion Reaction with Amines under Ultrasonic Conditions: A Divergent Synthesis of Ureas, Thioureas and Azaheterocycles

An Efficient Route to 3-Amidylindolesviaa Palladium- Catalyzed Tandem Reaction of 2-Alkynylanilines with Isocyanides

(2013) Guanyinsheng Qiu et al.   ADVANCED SYNTHESIS & CATALYSIS

Three-Component Metal-Free Arylation of Isocyanides

(2013) Unnamatla M. V. Basavanag et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Migratory Insertion of Isocyanides: An Emerging Platform in Cross-Coupling Chemistry

(2013) Tjøstil Vlaar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dual 1,3-dipolar cycloaddition of carbon dioxide: two CO bonds of CO2 react in one reaction

(2013) Li-Li Zhao et al.   CHEMICAL COMMUNICATIONS

Recent advances in isocyanide insertion chemistry

(2013) Guanyinsheng Qiu et al.   CHEMICAL SOCIETY REVIEWS

Unravelling the labyrinth of palladium-catalysed reactions involving isocyanides

(2013) Stuart Lang   CHEMICAL SOCIETY REVIEWS

Cobalt-Catalyzed Oxidative Isocyanide Insertion to Amine-Based Bisnucleophiles: Diverse Synthesis of Substituted 2-Aminobenzimidazoles, 2-Aminobenzothiazoles, and 2-Aminobenzoxazoles

(2013) Tong-Hao Zhu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Sustainable routes to polyurethane precursors

(2013) Oliver Kreye et al.   GREEN CHEMISTRY

Isocyanide-Based Multicomponent Reactions: Catalyst-Free Stereoselective Construction of Polycyclic Spiroindolines

(2013) Xiang Wang et al.   ORGANIC LETTERS

Palladium-Catalyzed Carbonylation of Amines: Switchable Approaches to Carbamates and N,N′-Disubstituted Ureas

(2012) Zheng-Hui Guan et al.   ADVANCED SYNTHESIS & CATALYSIS

Sustainable Synthesis of Diverse Privileged Heterocycles by Palladium-Catalyzed Aerobic Oxidative Isocyanide Insertion

(2012) Tjøstil Vlaar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Preparation of quinazolino[3,2-a]quinazolines via a palladium-catalyzed three-component reaction of carbodiimide, isocyanide, and amine

(2012) Guanyinsheng Qiu et al.   CHEMICAL COMMUNICATIONS

A palladium-catalyzed three-component reaction for the preparation of quinazolin-4(3H)-imines

(2012) Guanyinsheng Qiu et al.   CHEMICAL COMMUNICATIONS

Highly Enantioselective Epoxidation Catalyzed by Cinchona Thioureas: Synthesis of Functionalized Terminal Epoxides Bearing a Quaternary Stereogenic Center

(2012) Alessio Russo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cobalt-Catalyzed Vinylation of Aromatic Halides Using β-Halostyrene: Experimental and DFT Studies

(2012) Aurélien Moncomble et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Cross-Coupling of Aryl Chlorides and Triflates with Sodium Cyanate: A Practical Synthesis of Unsymmetrical Ureas

(2012) Ekaterina V. Vinogradova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzed Ortho-Arylation of Aromatic Imines with Aryl Chlorides

(2012) Ke Gao et al.   ORGANIC LETTERS

Palladium-Catalyzed Trifluoromethylation of Aromatic C–H Bond Directed by an Acetamino Group

(2012) Li-Sheng Zhang et al.   ORGANIC LETTERS

TFA-catalyzed C–N bond activation of enamides with indoles: efficient synthesis of 3,3-bisindolylpropanoates and other bisindolylalkanes

(2012) Hai-Yan Xu et al.   TETRAHEDRON

An intramolecular nitro-Mannich route to functionalised tetrahydroquinolines

(2012) James C. Anderson et al.   TETRAHEDRON LETTERS

Efficient organocatalytic asymmetric synthesis of 2-amino-4H-chromene-3-carbonitrile derivatives

(2012) Yu Gao et al.   TETRAHEDRON-ASYMMETRY

Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349

(2012) Zhonghua Pei et al.   ACS Medicinal Chemistry Letters

Discovery and Structural Modification of 1-Phenyl-3-(1-phenylethyl)urea Derivatives as Inhibitors of Complement

(2012) Mei Zhang et al.   ACS Medicinal Chemistry Letters

Discovery of AC710, a Globally Selective Inhibitor of Platelet-Derived Growth Factor Receptor-Family Kinases

(2012) Gang Liu et al.   ACS Medicinal Chemistry Letters

Discovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models

(2012) Pam Albaugh et al.   ACS Medicinal Chemistry Letters

Efficient synthesis of optically active 4-nitro-cyclohexanones via bifunctional thiourea-base catalyzed double-Michael addition of nitromethane to dienones

(2011) Bin Wu et al.   CHEMICAL COMMUNICATIONS

Rhodium-Catalyzed Annulation of N-Benzoylsulfonamide with Isocyanide through CH Activation

(2011) Chen Zhu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of 4-Aminoquinazolines by Palladium-Catalyzed Intramolecular Imidoylation of N-(2-Bromoaryl)amidines

(2011) Gitte Van Baelen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Synthesis of 4-Aminophthalazin-1(2H)-ones by Isocyanide Insertion

(2011) Tjøstil Vlaar et al.   ORGANIC LETTERS

Enantioselective Enolate Protonation in Sulfa–Michael Addition to α-SubstitutedN-Acryloyloxazolidin-2-ones with Bifunctional Organocatalyst

(2011) Nirmal K. Rana et al.   ORGANIC LETTERS

Cobalt-Catalyzed Coupling of Alkyl Grignard Reagent with Benzamide and 2-Phenylpyridine Derivatives through Directed C–H Bond Activation under Air

(2011) Quan Chen et al.   ORGANIC LETTERS

Highly Enantioselective Synthesis of Polysubstituted TetrahydroquinolinesviaOrganocatalytic Michael/Aza-Henry Tandem Reactions

(2011) Zhen-Xin Jia et al.   ORGANIC LETTERS

Palladium-Catalyzed Intramolecular C(sp2)–H Amidination by Isonitrile Insertion Provides Direct Access to 4-Aminoquinazolines fromN-Arylamidines

(2011) Yong Wang et al.   ORGANIC LETTERS

Asymmetric synthesis of trifluoromethyl substituted dihydropyrans via organocatalytic cascade Michael–hemiketalization reaction

(2011) Jin-jia Wang et al.   TETRAHEDRON

Ultrasound irradiation promoted catalyst-free construction of formamidine framework using isocyanide as building blocks

(2011) Tong-Hao Zhu et al.   TETRAHEDRON LETTERS

Asymmetric Mannich reactions catalyzed by cinchona alkaloid thiourea: enantioselective one-pot synthesis of novel β-amino ester derivatives

(2011) Song Bai et al.   TETRAHEDRON-ASYMMETRY

An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS

(2011) Félix Calderón et al.   ACS Medicinal Chemistry Letters

Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility

(2011) Lanqi Jia et al.   ACS Medicinal Chemistry Letters

Direct Cross-Coupling of CH Bonds with Grignard Reagents through Cobalt Catalysis

(2010) Bin Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cobalt-Catalyzed Cross-Coupling Reactions

(2010) Gérard Cahiez et al.   CHEMICAL REVIEWS

Discovery of the Dual Orexin Receptor Antagonist [(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia

(2010) Christopher D. Cox et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of both Enantiomers of Hemiesters by Enantioselective Methanolysis of Meso Cyclic Anhydrides Catalyzed by α-Amino Acid-Derived Chiral Thioureas†

(2010) Rubén Manzano et al.   JOURNAL OF ORGANIC CHEMISTRY

Cobalt-catalyzed intramolecular C–N and C–O cross-coupling reactions: synthesis of benzimidazoles and benzoxazoles

(2010) Prasenjit Saha et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

DOSY NMR for monitoring self aggregation of bifunctional organocatalysts: increasing enantioselectivity with decreasing catalyst concentration

(2010) Hyeong Bin Jang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

NHC-Stabilized Gold(I) Complexes: Suitable Catalysts for 6-exo-dig Heterocyclization of 1-(o-Ethynylaryl)ureas

(2010) Ana Gimeno et al.   ORGANIC LETTERS

Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor

(2010) Douglas S. Johnson et al.   ACS Medicinal Chemistry Letters

Strategies for Innovation in Multicomponent Reaction Design

(2009) Bruce Ganem   ACCOUNTS OF CHEMICAL RESEARCH

Room-Temperature Palladium-Catalyzed CH Activation:ortho-Carbonylation of Aniline Derivatives

(2009) Chris E. Houlden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Natural Product Synthesis Using Multicomponent Reaction Strategies

(2009) Barry B. Touré et al.   CHEMICAL REVIEWS

(Thio)urea organocatalysis—What can be learnt from anion recognition?

(2009) Zhiguo Zhang et al.   CHEMICAL SOCIETY REVIEWS

A 1,8-Naphthyridone Derivative Targets the HIV-1 Tat-Mediated Transcription and Potently Inhibits the HIV-1 Replication

(2009) Serena Massari et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation

(2008) Jessica S. Fortin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Asymmetric catalysis with bifunctional cinchona alkaloid-based urea and thiourea organocatalysts

(2008) Stephen J. Connon   CHEMICAL COMMUNICATIONS

Cobalt-catalyzed cross-coupling reactions

(2008) Corinne Gosmini et al.   CHEMICAL COMMUNICATIONS

Synthesis of functionalised diarylmethanes via a cobalt-catalysed cross-coupling of arylzinc species with benzyl chlorides

(2008) Muriel Amatore et al.   CHEMICAL COMMUNICATIONS

Chiral amine-thioureas bearing multiple hydrogen bonding donors: highly efficient organocatalysts for asymmetric Michael addition of acetylacetone to nitroolefins

(2008) Chun-Jiang Wang et al.   CHEMICAL COMMUNICATIONS

Distinct Reactivity of Pd(OTs)2: The Intermolecular Pd(II)-Catalyzed 1,2-Carboamination of Dienes

(2008) Chris E. Houlden et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Heterobimetallic Cobalt/Rhodium Nanoparticle-Catalyzed Carbonylative Cycloaddition of 2-Alkynylanilines to Oxindoles

(2008) Ji Hoon Park et al.   ORGANIC LETTERS