Enantioselective Rhodium-Catalyzed Addition of Arylboronic Acids to Trifluoromethyl Ketones

Discovery of a new binding mode for a series of liver X receptor agonists

(2012) David J. Kopecky et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Rhodium(I)/Diene-Catalyzed Addition Reactions of Arylborons with Ketones

(2012) Yuan-Xi Liao et al.   ORGANIC LETTERS

Enantioselective Rh(I)-Catalyzed Cyclization of Arylboron Compounds onto Ketones

(2012) Darryl W. Low et al.   ORGANIC LETTERS

Rh(I)-catalyzed asymmetric addition of arylboronic acids to NH isatins

(2012) Jiangyang Gui et al.   TETRAHEDRON-ASYMMETRY

Asymmetric Autocatalysis Enables an Improved Synthesis of Efavirenz

(2011) Nicka Chinkov et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Alkynylation of Trifluoromethyl Ketones: Pronounced Metal Fluoride Effects and Implications of Zinc-to-Titanium Transmetallation

(2011) Guang-Wu Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Application of 2,6-Bis(trifluoromethyl)-4-pyridyl Phosphanes: The Most Electron-Poor Aryl Phosphanes with Moderate Bulkiness

(2011) Toshinobu Korenaga et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed, Highly Enantioselective 1,2-Addition of Aryl Boronic Acids to α-Ketoesters and α-Diketones Using Simple, Chiral Sulfur-Olefin Ligands

(2011) Ting-Shun Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A New Synthetic Approach to Efavirenz through Enantioselective Trifluoromethylation by Using the Ruppert-Prakash Reagent

(2011) Hiroyuki Kawai et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Potent and Orally Efficacious 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor HSD-016

(2011) Zhao-Kui Wan et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral Allene-Containing Phosphines in Asymmetric Catalysis

(2011) Feng Cai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ru/Me-BIPAM-Catalyzed Asymmetric Addition of Arylboronic Acids to Aliphatic Aldehydes and α-Ketoesters

(2011) Yasunori Yamamoto et al.   MOLECULES

Catalytic Asymmetric Addition of Arylboronic Acids to Isatins usingC2-Symmetric CationicN-Heterocyclic Carbenes (NHCs) Pd2+Diaqua Complexes as Catalysts

(2011) Zhen Liu et al.   ORGANIC LETTERS

N-(Heteroarenesulfonyl)prolinamides-Catalyzed Aldol Reaction between Acetone and Aryl Trihalomethyl Ketones

(2011) Noriyuki Hara et al.   ORGANIC LETTERS

A New Class of Urea-Substituted Cinchona Alkaloids Promote Highly Enantioselective Nitroaldol reactions of Trifluoromethylketones

(2011) Carole Palacio et al.   ORGANIC LETTERS

Rhodium-Catalyzed Asymmetric Arylation

(2011) Ping Tian et al.   ACS Catalysis

Transition metal-catalyzed addition reactions of arylboronic acids with alkyl 2-formylbenzoates: efficient access to chiral 3-substituted phthalides

(2010) Chun-Hui Xing et al.   CHEMICAL COMMUNICATIONS

Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

(2010) Jing Nie et al.   CHEMICAL REVIEWS

Copper Catalyzed Asymmetric Propargylation of Aldehydes

(2010) Daniel R. Fandrick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel Axially Chiral Phosphine Ligand with a Fluoro Alcohol Moiety for Rh-Catalyzed Asymmetric Arylation of Aromatic Aldehydes

(2010) Satoshi Morikawa et al.   ORGANIC LETTERS

Cinchona Alkaloid-Catalyzed Asymmetric Trifluoromethylation of Alkynyl Ketones with Trimethylsilyl Trifluoromethane

(2010) Hiroyuki Kawai et al.   ORGANIC LETTERS

A chiral Rh–phosphite complex displaying high activity in the enantioselective Rh-catalyzed addition of arylboronic acids to carbonyl compounds: when and why atropos is better than tropos

(2010) Varsha R. Jumde et al.   TETRAHEDRON-ASYMMETRY

Me-bipam for Enantioselective Ruthenium(II)-Catalyzed Arylation of Aldehydes with Arylboronic Acids

(2009) Yasunori Yamamoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The concise synthesis of chiral tfb ligands and their application to the rhodium-catalyzed asymmetric arylation of aldehydes

(2009) Takahiro Nishimura et al.   CHEMICAL COMMUNICATIONS

Enantioselective Synthesis of β-Trifluoromethyl-β-lactones via NHC-Catalyzed Ketene−Ketone Cycloaddition Reactions

(2009) Xiao-Na Wang et al.   ORGANIC LETTERS

Novel, Tunable, and Efficient Chiral Bisdihydrobenzooxaphosphole Ligands for Asymmetric Hydrogenation

(2009) Wenjun Tang et al.   ORGANIC LETTERS

The history of antiretrovirals: key discoveries over the past 25 years

(2009) Erik De Clercq   REVIEWS IN MEDICAL VIROLOGY

Recent advances in enantioselective trifluoromethylation reactions

(2009) Norio Shibata et al.   TETRAHEDRON-ASYMMETRY

Enantioselective Rhodium-Catalyzed Addition of Arylboronic Acids to α-Ketoesters

(2008) Hai-Feng Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective organocatalyzed Henry reaction with fluoromethyl ketones

(2008) Marco Bandini et al.   CHEMICAL COMMUNICATIONS

Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions

(2008) Jun-An Ma et al.   CHEMICAL REVIEWS

Discovery of Novel, Potent Benzamide Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model▽

(2008) Lisa D. Julian et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Novel Enantiopure BiphenylP,N-Ligands and Application in Palladium-Catalyzed Asymmetric Addition of Arylboronic Acids toN-Benzylisatin

(2008) Hongshan Lai et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Enantioselective Addition of Diethylzinc to Trifluoromethyl Ketones

(2008) Kimberly Yearick et al.   ORGANIC LETTERS

Palladium(II)-catalyzed intramolecular addition of arylboronic acids to ketones

(2008) Guixia Liu et al.   TETRAHEDRON

An enantioselective nucleophilic addition of α,β-unsaturated trifluoromethylketones catalyzed by l-proline derivatives

(2007) Dehui Zhang et al.   TETRAHEDRON