Construction of Contiguous Tetrasubstituted Carbon Stereocenters by Intramolecular Crossed Benzoin Reactions Catalyzed by N-Heterocyclic Carbene (NHC) Organocatalyst

Recent Developments in Asymmetric Organocatalytic Domino Reactions

(2012) Hélène Pellissier   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective cyclopropanation of enals by oxidative N-heterocyclic carbene catalysis

(2012) Anup Biswas et al.   CHEMICAL COMMUNICATIONS

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

Extending NHC-Catalysis: Coupling Aldehydes with Unconventional Reaction Partners

(2011) Akkattu T. Biju et al.   ACCOUNTS OF CHEMICAL RESEARCH

Designing N-Heterocyclic Carbenes: Simultaneous Enhancement of Reactivity and Enantioselectivity in the Asymmetric Hydroacylation of Cyclopropenes

(2011) Fan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Synthesis of α-Amino Acid Derivatives by an NHC-Catalyzed Intermolecular Stetter Reaction

(2011) Thierry Jousseaume et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Asymmetric NHC-Catalyzed Hydroacylation of Unactivated Alkenes

(2011) Isabel Piel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions

(2011) Albert Moyano et al.   CHEMICAL REVIEWS

Dual Activation in N-Heterocyclic Carbene-organocatalysis

(2011) Keiichi Hirano et al.   CHEMISTRY LETTERS

N-Heterocyclic Carbene-Catalyzed (4 + 2) Cycloaddition/Decarboxylation of Silyl Dienol Ethers with α,β-Unsaturated Acid Fluorides

(2011) Sarah J. Ryan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis oftrans-γ-Lactams

(2011) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Intermolecular Stetter Reaction of Enals with Nitroalkenes: Enhancement of Catalytic Efficiency through Bifunctional Additives

(2011) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Dihydropyridinones via NHC-Catalyzed Aza-Claisen Reaction

(2011) Benedikt Wanner et al.   ORGANIC LETTERS

NHC-Catalyzed/Titanium(IV)−Mediated Highly Diastereo- and Enantioselective Dimerization of Enals

(2011) Daniel T. Cohen et al.   ORGANIC LETTERS

Highly Enantioselective Intermolecular Stetter Reactions of β-Aryl Acceptors: α-Ketoester Moiety as Handle for Activation and Synthetic Manipulations

(2011) Eduardo Sánchez-Larios et al.   ORGANIC LETTERS

Mechanistic Investigation of the Enantioselective Intramolecular Stetter Reaction: Proton Transfer Is the First Irreversible Step

(2011) Jennifer L. Moore et al.   ORGANIC LETTERS

Highly Stereoselective Synthesis of 1,2,3-Trisubstituted Indanes via Oxidative N-Heterocyclic Carbene-Catalyzed Cascades

(2011) Anup Biswas et al.   ORGANIC LETTERS

Efficient Synthesis of Benzofuranones: N-Heterocyclic Carbene (NHC)/Base-Catalyzed Hydroacylation–Stetter–Rearrangement Cascade

(2011) Mohan Padmanaban et al.   ORGANIC LETTERS

N-Heterocyclic carbene catalyzed intramolecular crossed aldehyde–ketone benzoin condensation in the chalcone of o-phthalaldehyde: a facile synthesis of naphthalenones

(2011) Shravankumar Kankala et al.   TETRAHEDRON LETTERS

NHC-catalysed, chemoselective crossed-acyloin reactions

(2011) Christopher A. Rose et al.   Chemical Science

Enantioselective Synthesis of Spirocyclic Oxindole-β-lactones via N-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes and Isatins

(2010) Xiao-Na Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Development of Highly Selective Organic Reactions Catalyzed by Designed Amine Organocatalysts

(2010) Taichi Kano et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

N-heterocyclic carbene catalysed asymmetric cross-benzoin reactions of heteroaromatic aldehydes with trifluoromethyl ketones

(2010) Dieter Enders et al.   CHEMICAL COMMUNICATIONS

Electrogenerated NHC as an organocatalyst in the Staudinger reaction

(2010) Marta Feroci et al.   CHEMICAL COMMUNICATIONS

Metal-catalyzed asymmetric conjugate addition reaction: formation of quaternary stereocenters

(2010) Christine Hawner et al.   CHEMICAL COMMUNICATIONS

N-Heterocyclic carbene-catalyzed tandem aza-benzoin/Michael reactions: on site reversal of the reactivity of N-Boc imines

(2010) Ke-Jia Wu et al.   CHEMICAL COMMUNICATIONS

Theoretical Investigations towards the Staudinger Reaction Catalyzed by N-Heterocyclic Carbene: Mechanism and Stereoselectivity

(2010) Ke Tang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of Indole-Fused Dihydropyranones via Catalytic Cycloaddition of Ketenes and 3-Alkylenyloxindoles

(2010) Hui Lv et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Chemoselective Direct Crossed Aliphatic−Aromatic Acyloin Condensations with Triazolium-Derived Carbene Catalysts

(2010) Sarah E. O’Toole et al.   JOURNAL OF ORGANIC CHEMISTRY

CooperativeN-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenolates

(2010) Benoit Cardinal-David et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene-Catalyzed Cascade Reaction Involving the Hydroacylation of Unactivated Alkynes

(2010) Akkattu T. Biju et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Enantioselective Claisen Rearrangement Catalyzed by N-Heterocyclic Carbenes

(2010) Juthanat Kaeobamrung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC Catalyzed Oxidations of Aldehydes to Esters: Chemoselective Acylation of Alcohols in Presence of Amines

(2010) Suman De Sarkar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NHC-catalysed annulation of enals to tethered dienones: efficient synthesis of bicyclic dienes

(2010) Vijay Nair et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic Enantioselective Total Syntheses of Bakkenolides I, J, and S: Application of a Carbene-Catalyzed Desymmetrization

(2010) Eric M. Phillips et al.   ORGANIC LETTERS

Sequential Organocatalytic Stetter and Michael-Aldol Condensation Reaction: Asymmetric Synthesis of Fully Substituted Cyclopentenes via a [1 + 2 + 2] Annulation Strategy

(2010) Bor-Cherng Hong et al.   ORGANIC LETTERS

NHC-Catalyzed Spiro Bis-Indane Formation via Domino Stetter−Aldol−Michael and Stetter−Aldol−Aldol Reactions

(2010) Eduardo Sánchez-Larios et al.   ORGANIC LETTERS

Chiral N-heterocyclic carbene-catalyzed generation of ester enolate equivalents from  , -unsaturated aldehydes for enantioselective Diels-Alder reactions

(2010) J. Kaeobamrung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multicatalytic, asymmetric Michael/Stetter reaction of salicylaldehydes and activated alkynes

(2010) C. M. Filloux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chiral Phosphoric Acids as Versatile Catalysts for Enantioselective Transformations

(2010) Masahiro Terada   SYNTHESIS-STUTTGART

Enantioselective Synthesis of DihydrocoumarinsviaN-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes ando-Quinone Methides

(2009) Hui Lv et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic amide formation with α′-hydroxyenones as acylating reagents

(2009) Pei-Chen Chiang et al.   CHEMICAL COMMUNICATIONS

Organocatalysis—after the gold rush

(2009) Søren Bertelsen et al.   CHEMICAL SOCIETY REVIEWS

Highly Enantioselective Benzoin Condensation Reactions Involving a Bifunctional Protic Pentafluorophenyl-Substituted Triazolium Precatalyst

(2009) Louise Baragwanath et al.   JOURNAL OF ORGANIC CHEMISTRY

Diastereoselective Synthesis of 4-Hydroxytetralones via a Cascade Stetter−Aldol Reaction Catalyzed byN-Heterocyclic Carbenes

(2009) Fang-Gang Sun et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Synthesis of Functionalized Cyclopentanones via a Multicatalytic Secondary Amine/N-Heterocyclic Carbene Catalyzed Cascade Sequence

(2009) Stephen P. Lathrop et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Intermolecular Stetter Reaction of Heterocyclic Aldehydes with Nitroalkenes: Backbone Fluorination Improves Selectivity

(2009) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of Bicyclic Tertiary Alcohols with Quaternary Stereocenters via Intramolecular Crossed Benzoin Reactions Catalyzed byN-Heterocyclic Carbenes

(2009) Tadashi Ema et al.   ORGANIC LETTERS

Efficient Construction of Polycyclic Derivatives via a Highly Selective CuI-Catalyzed Domino Reductive-Aldol Cyclization

(2009) Julia Deschamp et al.   ORGANIC LETTERS

Novel Nucleophilic Heterocyclic Carbene Mediated Stereoselective Conjugate Addition of Enals to Nitrostyrenes via Homoenolate§

(2009) Vijay Nair et al.   ORGANIC LETTERS

Organocatalytic Formation of Quaternary Stereocenters

(2009) Marco Bella et al.   SYNTHESIS-STUTTGART

Stereoselective Synthesis of γ-ButyrolactonesviaOrganocatalytic Annulations of Enals and Keto Esters

(2008) Yi Li et al.   ADVANCED SYNTHESIS & CATALYSIS

[4+2] Cycloaddition of Ketenes withN-Benzoyldiazenes Catalyzed by N-Heterocyclic Carbenes

(2008) Xue-Liang Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric intermolecular Stetter reactions catalyzed by a novel triazolium derived N-heterocyclic carbene

(2008) Dieter Enders et al.   CHEMICAL COMMUNICATIONS

d-Camphor-derived triazolium salts for catalytic intramolecular crossed aldehyde–ketone benzoin reactions

(2008) Yi Li et al.   CHEMICAL COMMUNICATIONS

Cyclophane-Type Imidazolium Salts with Planar Chirality as a New Class of N-Heterocyclic Carbene Precursors

(2008) Yuki Matsuoka et al.   CHEMISTRY-A EUROPEAN JOURNAL

ChiralN-Heterocyclic Carbene-Catalyzed Formal [4+2] Cycloaddition of Ketenes with Enones: Highly Enantioselective Synthesis oftrans- andcis-δ-Lactones

(2008) Yan-Rong Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Scope of the Asymmetric Intramolecular Stetter Reaction Catalyzed by Chiral Nucleophilic Triazolinylidene Carbenes

(2008) Javier Read de Alaniz et al.   JOURNAL OF ORGANIC CHEMISTRY

Formal Cycloaddition of Disubstituted Ketenes with 2-Oxoaldehydes Catalyzed by Chiral N-Heterocyclic Carbenes

(2008) Lin He et al.   JOURNAL OF ORGANIC CHEMISTRY

Lessons from Nature: Biomimetic Organocatalytic Carbon−Carbon Bond Formations§

(2008) Dieter Enders et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Amination of Homoenolates Catalyzed byN-Heterocyclic Carbenes

(2008) Audrey Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Diastereo- and Enantioselective Additions of Homoenolates to Nitrones Catalyzed byN-Heterocyclic Carbenes

(2008) Eric M. Phillips et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral NHC-Catalyzed Oxodiene Diels−Alder Reactions with α-Chloroaldehyde Bisulfite Salts

(2008) Ming He et al.   ORGANIC LETTERS

Catalytic Asymmetric Stetter Reaction Onto Vinylphosphine Oxides and Vinylphosphonates

(2008) Steven C. Cullen et al.   ORGANIC LETTERS

Synthesis of anN-Mesityl Substituted Chiral Imidazolium Salt for NHC-Catalyzed Reactions

(2008) Justin R. Struble et al.   ORGANIC LETTERS

NHC-Catalyzed Reactions of Aryloxyacetaldehydes: A Domino Elimination/Conjugate Addition/Acylation Process for the Synthesis of Substituted Coumarins

(2008) Eric M. Phillips et al.   ORGANIC LETTERS

Development of Chiral Bicyclic Triazolium Salt Organic Catalysts: The Importance of theN-Aryl Substituent

(2007) Tomislav Rovis   CHEMISTRY LETTERS

Enantioselective, NHC-Catalyzed Bicyclo-β-Lactam Formation via Direct Annulations of Enals and UnsaturatedN-Sulfonyl Ketimines

(2007) Ming He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral N-Heterocyclic Carbene Catalyzed Staudinger Reaction of Ketenes with Imines:  Highly Enantioselective Synthesis ofN-Boc β-Lactams

(2007) Yan-Rong Zhang et al.   ORGANIC LETTERS