Hydrogels and Scaffolds for Immunomodulation

Engineering vaccines and niches for immune modulation

(2014) Alberto Purwada et al.   Acta Biomaterialia

PEG–Maleimide Hydrogels for Protein and Cell Delivery in Regenerative Medicine

(2013) Andrés J. García   ANNALS OF BIOMEDICAL ENGINEERING

The Thiol-Michael Addition Click Reaction: A Powerful and Widely Used Tool in Materials Chemistry

(2013) Devatha P. Nair et al.   CHEMISTRY OF MATERIALS

Cancer vaccines: Material breach

(2013) Elie Dolgin   NATURE

Macroscale delivery systems for molecular and cellular payloads

(2013) Cathal J. Kearney et al.   NATURE MATERIALS

Engineering synthetic vaccines using cues from natural immunity

(2013) Darrell J. Irvine et al.   NATURE MATERIALS

Advances in targeting cell surface signalling molecules for immune modulation

(2013) Sheng Yao et al.   NATURE REVIEWS DRUG DISCOVERY

PLG Scaffold Delivered Antigen-Specific Regulatory T Cells Induce Systemic Tolerance in Autoimmune Diabetes

(2013) John G. Graham et al.   TISSUE ENGINEERING PART A

Peptide nanofiber hydrogel adjuvanted live virus vaccine enhances cross-protective immunity to porcine reproductive and respiratory syndrome virus

(2013) Xiangdong Li et al.   VACCINE

Pharmacologically Triggered Hydrogel for Scheduling Hepatitis B Vaccine Administration

(2013) Raphael J. Gübeli et al.   Scientific Reports

Engineering Nano- and Microparticles to Tune Immunity

(2012) James J. Moon et al.   ADVANCED MATERIALS

Smart Self-Assembled Hybrid Hydrogel Biomaterials

(2012) Jindřich Kopeček et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-assembling nanoparticles for intra-articular delivery of anti-inflammatory proteins

(2012) Rachel E. Whitmire et al.   BIOMATERIALS

Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope

(2012) Jai S. Rudra et al.   BIOMATERIALS

Novel thermal-sensitive hydrogel enhances both humoral and cell-mediated immune responses by intranasal vaccine delivery

(2012) Youbin Wu et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Recognizing and reversing the immunosuppressive tumor microenvironment of head and neck cancer

(2012) Charles C. L. Tong et al.   IMMUNOLOGIC RESEARCH

Combination delivery of TGF-β inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy

(2012) Jason Park et al.   NATURE MATERIALS

The problems and promises of research into human immunology and autoimmune disease

(2012) Bart O Roep et al.   NATURE MEDICINE

Optimization of current and future therapy for autoimmune diseases

(2012) Lawrence Steinman et al.   NATURE MEDICINE

Designing Cell-Compatible Hydrogels for Biomedical Applications

(2012) D. Seliktar   SCIENCE

Maleimide Cross-Linked Bioactive PEG Hydrogel Exhibits Improved Reaction Kinetics and Cross-Linking for Cell Encapsulation and In Situ Delivery

(2011) Edward A. Phelps et al.   ADVANCED MATERIALS

Thermal-sensitive hydrogel as adjuvant-free vaccine delivery system for H5N1 intranasal immunization

(2011) Youbin Wu et al.   BIOMATERIALS

Solid freeform fabrication of designer scaffolds of hyaluronic acid for nerve tissue engineering

(2011) Shalu Suri et al.   BIOMEDICAL MICRODEVICES

An injectable synthetic immune-priming center mediates efficient T-cell class switching and T-helper 1 response against B cell lymphoma

(2011) Ankur Singh et al.   JOURNAL OF CONTROLLED RELEASE

Advanced molecular design of biopolymers for transmucosal and intracellular delivery of chemotherapeutic agents and biological therapeutics

(2011) William B. Liechty et al.   JOURNAL OF CONTROLLED RELEASE

In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles

(2011) C. M. Jewell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis

(2010) Jan Bondeson et al.   ARTHRITIS AND RHEUMATISM

Anticytokine Therapy for Osteoarthritis

(2010) Charles J. Malemud   DRUGS & AGING

Transcutaneous vaccination using a hydrogel patch induces effective immune responses to tetanus and diphtheria toxoid in hairless rat

(2010) Kazuhiko Matsuo et al.   JOURNAL OF CONTROLLED RELEASE

Hydrogel-Delivered GM-CSF Overcomes Nonresponsiveness to Hepatitis B Vaccine through the Recruitment and Activation of Dendritic Cells

(2010) H.-Y. Chou et al.   JOURNAL OF IMMUNOLOGY

Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines

(2010) Tomonori Nochi et al.   NATURE MATERIALS

Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes

(2010) Ana Clara Monsalvo et al.   NATURE MEDICINE

Cell-Laden Hydrogel Constructs of Hyaluronic Acid, Collagen, and Laminin for Neural Tissue Engineering

(2010) Shalu Suri et al.   TISSUE ENGINEERING PART A

A Protective Vaccine Delivery System for In Vivo T Cell Stimulation Using Nanoengineered Polymer Hydrogel Capsules

(2009) Amy Sexton et al.   ACS Nano

A paradigm for peptide vaccine delivery using viral epitopes encapsulated in degradable polymer hydrogel capsules

(2009) Siow-Feng Chong et al.   BIOMATERIALS

Polymer Scaffolds for Biomaterials Applications

(2009) Molly S. Shoichet   MACROMOLECULES

Materials engineering for immunomodulation

(2009) Jeffrey A. Hubbell et al.   NATURE

Infection-mimicking materials to program dendritic cells in situ

(2009) Omar A. Ali et al.   NATURE MATERIALS

Regulatory T cells as therapeutic targets in rheumatoid arthritis

(2009) Jonathan H. Esensten et al.   Nature Reviews Rheumatology

IL-17 as a future therapeutic target for rheumatoid arthritis

(2009) Wim B. van den Berg et al.   Nature Reviews Rheumatology

In Situ Regulation of DC Subsets and T Cells Mediates Tumor Regression in Mice

(2009) O. A. Ali et al.   Science Translational Medicine

Notch Ligand Presenting Acellular 3D Microenvironments for ex vivo Human Hematopoietic Stem-Cell Culture made by Layer-By-Layer Assembly

(2009) Jungwoo Lee et al.   Small

Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factors

(2008) Yuki Hori et al.   Acta Biomaterialia

Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism

(2008) M B Goldring et al.   ANNALS OF THE RHEUMATIC DISEASES

Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy

(2008) Yuki Hori et al.   BIOMATERIALS

Bioadhesive hydrogel microenvironments to modulate epithelial morphogenesis

(2008) I.-Ming Chung et al.   BIOMATERIALS

Humoral immune responses in patients vaccinated with 1–146 HER2 protein complexed with cholesteryl pullulan nanogel

(2008) Shinichi Kageyama et al.   CANCER SCIENCE

Self-Assembling Nanofibers Inhibit Glial Scar Formation and Promote Axon Elongation after Spinal Cord Injury

(2008) V. M. Tysseling-Mattiace et al.   JOURNAL OF NEUROSCIENCE

PEG Hydrogels for the Controlled Release of Biomolecules in Regenerative Medicine

(2008) Chien-Chi Lin et al.   PHARMACEUTICAL RESEARCH

Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients

(2008) F. S. Hodi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inverse opal hydrogel-collagen composite scaffolds as a supportive microenvironment for immune cell migration

(2007) Agnieszka N. Stachowiak et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Lymphoid tissue engineering: Invoking lymphoid tissue neogenesis in immunotherapy and models of immunity

(2007) Darrell J. Irvine et al.   SEMINARS IN IMMUNOLOGY