Metformin promotes irisin release from murine skeletal muscle independently of AMP-activated protein kinase activation

The essential role of transient receptor potential vanilloid 1 in simvastatin-induced activation of endothelial nitric oxide synthase and angiogenesis

(2014) K.-H. Su et al.   Acta Physiologica

Irisin - ‘New Kid on the Block in energy regulation’?

(2014) K. A. Mäkelä et al.   Acta Physiologica

Impaired structural and functional regeneration of skeletal muscles fromβ2-adrenoceptor knockout mice

(2014) M. T. Silva et al.   Acta Physiologica

The identification of irisin in human cerebrospinal fluid: influence of adiposity, metabolic markers, and gestational diabetes

(2014) Milan K. Piya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans

(2014) Paul Lee et al.   Cell Metabolism

Activation of a7 Nicotinic Acetylcholine Receptor Protects Against Oxidant Stress Damage Through Reducing Vascular Peroxidase-1 in a JNK Signaling-Dependent Manner in Endothelial Cells

(2014) Dong-Jie Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Characterization of the metabolic effects of irisin on skeletal musclein vitro

(2014) R. A. Vaughan et al.   DIABETES OBESITY & METABOLISM

Maternal serum and fetal cord blood irisin levels in gestational diabetes mellitus

(2014) Mehmet Aytac Yuksel et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Serum irisin concentration in women with gestational diabetes

(2014) Mariusz Kuzmicki et al.   GYNECOLOGICAL ENDOCRINOLOGY

Irisin stimulates muscle growth-related genes and regulates adipocyte differentiation and metabolism in humans

(2014) J Y Huh et al.   INTERNATIONAL JOURNAL OF OBESITY

Circulating Irisin in Healthy, Young Individuals: Day-Night Rhythm, Effects of Food Intake and Exercise, and Associations With Gender, Physical Activity, Diet, and Body Composition

(2014) Athanasios D. Anastasilakis et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Browning of white fat: does irisin play a role in humans?

(2014) Manuela Elsen et al.   JOURNAL OF ENDOCRINOLOGY

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

(2014) Anila K. Madiraju et al.   NATURE

Blockade of mitochondrial calcium uniporter prevents cardiac mitochondrial dysfunction caused by iron overload

(2013) J. Sripetchwandee et al.   Acta Physiologica

Good publication practice in physiology 2013: revised author guidelines for Acta Physiologica

(2013) P. B. Persson   Acta Physiologica

Caloric restriction ameliorates kidney ischaemia/reperfusion injury through PGC-1α-eNOS pathway and enhanced autophagy

(2013) J. Lempiäinen et al.   Acta Physiologica

Src homology 2-containing protein tyrosine phosphatase-2 acts as a negative regulator for MUC5AC transcription via the inhibition of the ERK1/2 MAPK signalling pathway in the airway

(2013) K. S. Song et al.   Acta Physiologica

Effects of two weeks of metformin treatment on whole-body glycocalyx barrier properties in db/db mice

(2013) Bart JM Eskens et al.   Cardiovascular Diabetology

AICAR inhibits PPARγ during monocyte differentiation to attenuate inflammatory responses to atherogenic lipids

(2013) Dmitry Namgaladze et al.   CARDIOVASCULAR RESEARCH

Functional remodelling of arterial endothelium during early postnatal development in rats

(2013) Dina Gaynullina et al.   CARDIOVASCULAR RESEARCH

Metformin revisited: A critical review of the benefit–risk balance in at-risk patients with type 2 diabetes

(2013) A.J. Scheen et al.   DIABETES & METABOLISM

Serum irisin levels in new-onset type 2 diabetes

(2013) Yeon-Kyung Choi et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

An increase in theAkkermansiaspp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice

(2013) Na-Ri Shin et al.   GUT

Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin Resistance

(2013) José María Moreno-Navarrete et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Lower circulating irisin is associated with type 2 diabetes mellitus

(2013) Jian-Jun Liu et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Are skeletal muscleFNDC5gene expression and irisin release regulated by exercise and related to health?

(2013) Satu Pekkala et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effects of obesity, diabetes and exercise onFndc5gene expression and irisin release in human skeletal muscle and adipose tissue:in vivoandin vitrostudies

(2013) Timea Kurdiova et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs

(2013) John N. Fain et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

FNDC5/Irisin Is Not Only a Myokine but Also an Adipokine

(2013) Arturo Roca-Rivada et al.   PLoS One

Evidence against a Beneficial Effect of Irisin in Humans

(2013) Silja Raschke et al.   PLoS One

Irisin, Two Years Later

(2013) Marta G. Novelle et al.   International Journal of Endocrinology

Early ischaemic preconditioning requires Akt- and PKA-mediated activation of eNOS via serine1176 phosphorylation

(2012) Changjun Yang et al.   CARDIOVASCULAR RESEARCH

Metformin Inhibits Growth Hormone-Mediated Hepatic PDK4 Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner

(2012) Y. D. Kim et al.   DIABETES

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise

(2012) Joo Young Huh et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Role of PKC and CaV1.2 in Detrusor Overactivity in a Model of Obesity Associated with Insulin Resistance in Mice

(2012) Luiz O. Leiria et al.   PLoS One

Cellular and molecular mechanisms of metformin: an overview

(2011) Benoit Viollet et al.   CLINICAL SCIENCE

Reduced Cell Proliferation and Neuroblast Differentiation in the Dentate Gyrus of High Fat Diet-Fed Mice are Ameliorated by Metformin and Glimepiride Treatment

(2011) Dae Young Yoo et al.   NEUROCHEMICAL RESEARCH

Metformin Reduces Body Weight Gain and Improves Glucose Intolerance in High-Fat Diet-Fed C57BL/6J Mice

(2010) Yukari Matsui et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-α in mice

(2010) A. Maida et al.   DIABETOLOGIA

Dysfunction of the Cholinergic Anti-Inflammatory Pathway Mediates Organ Damage in Hypertension

(2010) Dong-Jie Li et al.   HYPERTENSION

Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase

(2010) Kunihiro Hosono et al.   MOLECULAR CARCINOGENESIS

The economic burden of obesity worldwide: a systematic review of the direct costs of obesity

(2010) D. Withrow et al.   Obesity Reviews

Overexpressed α7 nicotinic acetylcholine receptor inhibited proinflammatory cytokine release in NIH3T3 cells

(2009) Dong-Jie Li et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING