Unique neuromyelitis optica pathology produced in naïve rats by intracerebral administration of NMO-IgG

Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica

(2013) Julien Ratelade et al.   ACTA NEUROPATHOLOGICA

Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

(2013) Tatsuro Misu et al.   ACTA NEUROPATHOLOGICA

Eosinophil pathogenicity mechanisms and therapeutics in neuromyelitis optica

(2013) Hua Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury

(2013) I. B. Wanner et al.   JOURNAL OF NEUROSCIENCE

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Neuromyelitis optica IgG and natural killer cells produce NMO lesions in mice without myelin loss

(2012) Julien Ratelade et al.   ACTA NEUROPATHOLOGICA

Enzymatic deglycosylation converts pathogenic neuromyelitis optica anti-aquaporin-4 immunoglobulin G into therapeutic antibody

(2012) Lukmanee Tradtrantip et al.   ANNALS OF NEUROLOGY

Complement-dependent Cytotoxicity in Neuromyelitis Optica Requires Aquaporin-4 Protein Assembly in Orthogonal Arrays

(2012) Puay-Wah Phuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Current concept of neuromyelitis optica (NMO) and NMO spectrum disorders

(2012) A. Jacob et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Region-specific expression of a water channel protein, aquaporin 4, on brain astrocytes

(2012) M. Aoyama et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Aquaporin 4 and neuromyelitis optica

(2012) Marios C Papadopoulos et al.   LANCET NEUROLOGY

Paucity of natural killer and cytotoxic T cells in human neuromyelitis optica lesions

(2012) Samira Saadoun et al.   NEUROREPORT

Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms

(2011) Hua Zhang et al.   ANNALS OF NEUROLOGY

Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica

(2011) Lukmanee Tradtrantip et al.   ANNALS OF NEUROLOGY

Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

(2011) Samira Saadoun et al.   ANNALS OF NEUROLOGY

Evidence against Cellular Internalizationin Vivoof NMO-IgG, Aquaporin-4, and Excitatory Amino Acid Transporter 2 in Neuromyelitis Optica

(2011) Julien Ratelade et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding Affinity and Specificity of Neuromyelitis Optica Autoantibodies to Aquaporin-4 M1/M23 Isoforms and Orthogonal Arrays

(2011) Jonathan M. Crane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T cell deficiency does not reduce lesions in mice produced by intracerebral injection of NMO-IgG and complement

(2011) Samira Saadoun et al.   JOURNAL OF NEUROIMMUNOLOGY

Autoimmunity in neuromyelitis optica and opticospinal multiple sclerosis: Astrocytopathy as a common denominator in demyelinating disorders

(2011) Jun-ichi Kira   JOURNAL OF THE NEUROLOGICAL SCIENCES

Intravenous Neuromyelitis Optica Autoantibody in Mice Targets Aquaporin-4 in Peripheral Organs and Area Postrema

(2011) Julien Ratelade et al.   PLoS One

Anti-aquaporin-4 antibody induces astrocytic cytotoxicity in the absence of CNS antigen-specific T cells

(2010) Makoto Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice

(2010) Samira Saadoun et al.   BRAIN

AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance

(2010) Sven Jarius et al.   Nature Reviews Neurology

Cobra venom factor: Structure, function, and humanization for therapeutic complement depletion

(2010) Carl-Wilhelm Vogel et al.   TOXICON

Intrathecal pathogenic anti–aquaporin-4 antibodies in early neuromyelitis optica

(2009) Jeffrey L. Bennett et al.   ANNALS OF NEUROLOGY

Neuromyelitis optica: Passive transfer to rats by human immunoglobulin

(2009) Makoto Kinoshita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reactive Astrocytes Form Scar-Like Perivascular Barriers to Leukocytes during Adaptive Immune Inflammation of the CNS

(2009) R. R. Voskuhl et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

The role of the anaphylatoxins in health and disease

(2009) Andreas Klos et al.   MOLECULAR IMMUNOLOGY

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism

(2009) Agnes Machnik et al.   NATURE MEDICINE

Complement activation in the peripheral nervous system following the spinal nerve ligation model of neuropathic pain☆

(2007) Margaret E. Levin et al.   PAIN