Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

Neuromyelitis optica lesions may inform multiple sclerosis heterogeneity debate

(2012) Wolfgang Brück et al.   ANNALS OF NEUROLOGY

Small-molecule inhibitors of NMO-IgG binding to aquaporin-4 reduce astrocyte cytotoxicity in neuromyelitis optica

(2012) Lukmanee Tradtrantip et al.   FASEB JOURNAL

Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content, or supramolecular assembly

(2012) Andrea Rossi et al.   GLIA

Neuromyelitis optica: Aquaporin-4 based pathogenesis mechanisms and new therapies

(2012) Julien Ratelade et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Potassium Channel KIR4.1 as an Immune Target in Multiple Sclerosis

(2012) Rajneesh Srivastava et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-Aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica

(2011) Lukmanee Tradtrantip et al.   ANNALS OF NEUROLOGY

Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

(2011) Samira Saadoun et al.   ANNALS OF NEUROLOGY

F-actin depolymerization accelerates clasmatodendrosis via activation of lysosome-derived autophagic astroglial death

(2011) H.J. Ryu et al.   BRAIN RESEARCH BULLETIN

Pain in neuromyelitis optica and its effect on quality of life: A cross-sectional study

(2011) Y. Kanamori et al.   NEUROLOGY

Review: The architecture of inflammatory demyelinating lesions: implications for studies on pathogenesis

(2011) H. Lassmann   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes

(2011) S. R. Hinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aquaporin-4 astrocytopathy in Baló’s disease

(2010) Takeshi Matsuoka et al.   ACTA NEUROPATHOLOGICA

Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination

(2010) Rakhi Sharma et al.   ACTA NEUROPATHOLOGICA

Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury

(2010) Romain Marignier et al.   BRAIN

Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice

(2010) Samira Saadoun et al.   BRAIN

Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis

(2010) Romana Höftberger et al.   GLIA

P2X7 receptor differentially modulates astroglial apoptosis and clasmatodendrosis in the rat brain following status epilepticus

(2010) Ji-Eun Kim et al.   HIPPOCAMPUS

Neuromyelitis optica: a demyelinating disease characterized by acute destruction and regeneration of perivascular astrocytes

(2010) John DE Parratt et al.   Multiple Sclerosis Journal

Astrocytic damage is far more severe than demyelination in NMO: A clinical CSF biomarker study

(2010) R. Takano et al.   NEUROLOGY

Absence of cortical demyelination in neuromyelitis optica

(2010) B. F. G. Popescu et al.   NEUROLOGY

Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo

(2009) Monika Bradl et al.   ANNALS OF NEUROLOGY

Intrathecal pathogenic anti–aquaporin-4 antibodies in early neuromyelitis optica

(2009) Jeffrey L. Bennett et al.   ANNALS OF NEUROLOGY

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Astrocytic Demise in the Developing Rat and Human Brain after Hypoxic-Ischemic Damage

(2009) Antoinette Gelot et al.   DEVELOPMENTAL NEUROSCIENCE

Marked increase in cerebrospinal fluid glial fibrillar acidic protein in neuromyelitis optica: an astrocytic damage marker

(2009) T Misu et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Astrocytic necrosis is induced by anti-aquaporin-4 antibody-positive serum

(2009) Makoto Kinoshita et al.   NEUROREPORT

Neurological autoimmunity targeting aquaporin-4

(2009) S.R. Hinson et al.   NEUROSCIENCE

Antibody to aquaporin-4 in the long-term course of neuromyelitis optica

(2008) S. Jarius et al.   BRAIN

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

Aquaporin-4–binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2

(2008) Shannon R. Hinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE