Killing of Escherichia coli by Crohnʼs Disease Monocyte-derived Macrophages and Its Enhancement by Hydroxychloroquine and Vitamin D

The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

(2014) Dirk Gevers et al.   Cell Host & Microbe

The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

(2014) Aleksandar D. Kostic et al.   GASTROENTEROLOGY

Coxiella burnetii Type IV Secretion-Dependent Recruitment of Macrophage Autophagosomes

(2014) C. G. Winchell et al.   INFECTION AND IMMUNITY

Longitudinal study of murine microbiota activity and interactions with the host during acute inflammation and recovery

(2014) Clarissa Schwab et al.   ISME Journal

Tropheryma whipplei and Whipple's disease

(2014) Florence Fenollar et al.   JOURNAL OF INFECTION

Impact of vitamin D on immune function: lessons learned from genome-wide analysis

(2014) Rene F. Chun et al.   Frontiers in Physiology

Antimicrobial therapies for Q fever

(2013) Gilbert J Kersh   Expert Review of Anti-Infective Therapy

Colonic mucosa-associated diffusely adherentafaC+ Escherichia coliexpressinglpfAandpksare increased in inflammatory bowel disease and colon cancer

(2013) Maelle Prorok-Hamon et al.   GUT

Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation

(2013) M Zaeem Cader et al.   GUT

Treatment of classic Whipple's disease: from in vitro results to clinical outcome

(2013) J.-C. Lagier et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response

(2012) Pierre Lapaquette et al.   CELLULAR MICROBIOLOGY

Defective tumor necrosis factor release from Crohnʼs disease macrophages in response to toll-like receptor activation: Relationship to phenotype and genome-wide association susceptibility loci

(2012) Gavin W. Sewell et al.   INFLAMMATORY BOWEL DISEASES

Multidrug Resistance Is Common in Escherichia coli Associated with Ileal Crohnʼs Disease

(2012) Belgin Dogan et al.   INFLAMMATORY BOWEL DISEASES

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Autophagy modulation as a potential therapeutic target for diverse diseases

(2012) David C. Rubinsztein et al.   NATURE REVIEWS DRUG DISCOVERY

Antibiotic Therapy in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis

(2011) Khurram J Khan et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Crohn disease–associated adherent-invasive E. coli bacteria target mouse and human Peyer’s patches via long polar fimbriae

(2011) Benoit Chassaing et al.   JOURNAL OF CLINICAL INVESTIGATION

Vitamin D Insufficiency

(2011) Clifford J. Rosen   NEW ENGLAND JOURNAL OF MEDICINE

Vitamin D and immune function: an overview

(2011) Martin Hewison   PROCEEDINGS OF THE NUTRITION SOCIETY

Vitamin D Is Required for IFN- -Mediated Antimicrobial Activity of Human Macrophages

(2011) M. Fabri et al.   Science Translational Medicine

Clinical trial: vitamin D3 treatment in Crohn’s disease - a randomized double-blind placebo-controlled study

(2010) S. P. Jørgensen et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Translocation of Crohn's disease Escherichia coli across M-cells: contrasting effects of soluble plant fibres and emulsifiers

(2010) C. L. Roberts et al.   GUT

SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages

(2010) Scott B Berger et al.   NATURE IMMUNOLOGY

Bacterial manipulation of innate immunity to promote infection

(2010) Lautaro Diacovich et al.   NATURE REVIEWS MICROBIOLOGY

Efficiency of hydroxychloroquine in the treatment of granulomatous complications in chronic granulomatous disease

(2009) Jean-Benoit Arlet et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

(2009) Andrew M. Smith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antimicrobial mechanisms of phagocytes and bacterial evasion strategies

(2009) Ronald S. Flannagan et al.   NATURE REVIEWS MICROBIOLOGY

Autophagy gene ATG16L1 influences susceptibility and disease location but not childhood-onset in Crohnʼs disease in Northern Europe

(2007) J. Van Limbergen et al.   INFLAMMATORY BOWEL DISEASES