标题
Therapeutic targeting of bile acids
作者
关键词
-
出版物
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Volume 309, Issue 4, Pages G209-G215
出版商
American Physiological Society
发表日期
2015-07-04
DOI
10.1152/ajpgi.00121.2015
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Effect of colesevelam on faecal bile acids and bowel functions in diarrhoea-predominant irritable bowel syndrome
- (2015) M. Camilleri et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid
- (2015) Gideon M. Hirschfield et al. GASTROENTEROLOGY
- Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
- (2015) Brent A Neuschwander-Tetri et al. LANCET
- Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance
- (2015) Sungsoon Fang et al. NATURE MEDICINE
- The response of patients with bile acid diarrhoea to the farnesoid X receptor agonist obeticholic acid
- (2014) J. R. F. Walters et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Genetic variation in GPBAR1 predisposes to quantitative changes in colonic transit and bile acid excretion
- (2014) Michael Camilleri et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Bile acids and the gut microbiome
- (2014) Jason M. Ridlon et al. CURRENT OPINION IN GASTROENTEROLOGY
- MECHANISMS IN ENDOCRINOLOGY: Bile acid sequestrants in type 2 diabetes: potential effects on GLP1 secretion
- (2014) David P Sonne et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades
- (2014) Alan F. Hofmann et al. JOURNAL OF LIPID RESEARCH
- Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
- (2014) Charlie G. Buffie et al. NATURE
- FXR is a molecular target for the effects of vertical sleeve gastrectomy
- (2014) Karen K. Ryan et al. NATURE
- FXR: the key to benefits in bariatric surgery?
- (2014) Folkert Kuipers et al. NATURE MEDICINE
- Harnessing Microbiota to Kill a Pathogen: Fixing the microbiota to treat Clostridium difficile infections
- (2014) Ying Taur et al. NATURE MEDICINE
- Dual Activation of the Bile Acid Nuclear Receptor FXR and G-Protein-Coupled Receptor TGR5 Protects Mice against Atherosclerosis
- (2014) Shinobu Miyazaki-Anzai et al. PLoS One
- Therapeutic uses of animal biles in traditional Chinese medicine: An ethnopharmacological, biophysical chemical and medicinal review
- (2014) David Q-H Wang WORLD JOURNAL OF GASTROENTEROLOGY
- Molecular mechanisms of hepatic apoptosis
- (2014) K Wang Cell Death & Disease
- Advances in understanding of bile acid diarrhea
- (2014) Michael Camilleri Expert Review of Gastroenterology & Hepatology
- Review article: controversies in the management of primary biliary cirrhosis and primary sclerosing cholangitis
- (2013) T. H. Karlsen et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Chenodeoxycholic acid stimulates Cl− secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells
- (2013) Mei Ao et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids
- (2013) Justine H. Zhang et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Irritable bowel syndrome-diarrhea: characterization of genotype by exome sequencing, and phenotypes of bile acid synthesis and colonic transit
- (2013) Michael Camilleri et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist
- (2013) Sama I. Sayin et al. Cell Metabolism
- Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease
- (2013) Sunder Mudaliar et al. GASTROENTEROLOGY
- Ursodeoxycholic acid attenuates colonic epithelial secretory function
- (2013) Orlaith B. Kelly et al. JOURNAL OF PHYSIOLOGY-LONDON
- Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner
- (2013) Andriy Myronovych et al. Obesity
- Bile acids and gut peptide secretion after bariatric surgery: A 1-year prospective randomized pilot trial
- (2013) Robert E. Steinert et al. Obesity
- The Receptor TGR5 Mediates the Prokinetic Actions of Intestinal Bile Acids and Is Required for Normal Defecation in Mice
- (2012) Farzad Alemi et al. GASTROENTEROLOGY
- Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 −/− mice
- (2012) Suzanne Devkota et al. NATURE
- Bile acids in the colon, from healthy to cytotoxic molecules
- (2012) Juan I. Barrasa et al. TOXICOLOGY IN VITRO
- Ursodeoxycholic acid and bile-acid mimetics as therapeutic agents for cholestatic liver diseases: An overview of their mechanisms of action
- (2012) Raoul Poupon Clinics and Research in Hepatology and Gastroenterology
- Meta-analysis: ursodeoxycholic acid for primary sclerosing cholangitis
- (2011) C. K. Triantos et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Effects of A3309, an Ileal Bile Acid Transporter Inhibitor, on Colonic Transit and Symptoms in Females With Functional Constipation
- (2011) Banny S Wong et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- A Randomized Placebo-Controlled Phase IIb Trial of A3309, A Bile Acid Transporter Inhibitor, for Chronic Idiopathic Constipation
- (2011) William D Chey et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- A Klothoβ Variant Mediates Protein Stability and Associates With Colon Transit in Irritable Bowel Syndrome With Diarrhea
- (2011) Banny S. Wong et al. GASTROENTEROLOGY
- Chenodeoxycholate in Females With Irritable Bowel Syndrome-Constipation: A Pharmacodynamic and Pharmacogenetic Analysis
- (2010) Archana S. Rao et al. GASTROENTEROLOGY
- Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system
- (2010) D. P. Poole et al. NEUROGASTROENTEROLOGY AND MOTILITY
- A New Mechanism for Bile Acid Diarrhea: Defective Feedback Inhibition of Bile Acid Biosynthesis
- (2009) Julian R.F. Walters et al. Clinical Gastroenterology and Hepatology
- Effects of Chenodeoxycholate and a Bile Acid Sequestrant, Colesevelam, on Intestinal Transit and Bowel Function
- (2009) Suwebatu T. Odunsi–Shiyanbade et al. Clinical Gastroenterology and Hepatology
- Colesevelam lowers glucose and lipid levels in type 2 diabetes: the clinical evidence
- (2009) Vivian A. Fonseca et al. DIABETES OBESITY & METABOLISM
- Lowering Low-Density Lipoprotein Cholesterol: Statins, Ezetimibe, Bile Acid Sequestrants, and Combinations: Comparative Efficacy and Safety
- (2009) Runhua Hou et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- High-dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis
- (2009) Keith D. Lindor et al. HEPATOLOGY
- Physiological concentrations of bile acids down-regulate agonist induced secretion in colonic epithelial cells
- (2009) Niamh Keating et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Bile-acid-induced cell injury and protection
- (2009) Maria J Perez et al. WORLD JOURNAL OF GASTROENTEROLOGY
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