Article
Biochemistry & Molecular Biology
Shu-Hua Chiang, Kia-Min Yang, Shiann-Cherng Sheu, Chih-Wei Chen
Summary: The study investigated the inhibition of DNA oxidative damage and LDL oxidation by royal jelly protein hydrolysates, finding that RJP-AF showed the most effective inhibition.
Article
Biochemistry & Molecular Biology
Anshika Gupta, James A. Imlay
Summary: Escherichia coli responds to hydrogen peroxide by inducing defenses that protect sensitive enzymes. While enzymes that repair oxidative lesions in vitro are not known to be induced by hydrogen peroxide, physiological levels of hydrogen peroxide pose a real threat to DNA and activate the base-excision-repair and SOS systems to enable propagation during prolonged stress.
MOLECULAR MICROBIOLOGY
(2022)
Review
Gastroenterology & Hepatology
Shiying Wu, Yongqiang Chen, Ziqi Chen, Fangtong Wei, Qingqing Zhou, Ping Li, Qing Gu
Summary: H. pylori colonization in the stomach induces inflammatory response and production of ROS and RNS, but the bacterium has developed strategies to counteract the harmful effects of ROS. However, the host's inability to eliminate H. pylori infection results in persistent ROS production, which may lead to chronic inflammation and gastric carcinogenesis.
Review
Biochemistry & Molecular Biology
Ignacio Gutierrez-del-Rio, Sara Lopez-Ibanez, Patricia Magadan-Corpas, Luis Fernandez-Calleja, Alvaro Perez-Valero, Mateo Tunon-Granda, Elisa M. Miguelez, Claudio J. Villar, Felipe Lombo
Summary: Synthetic antioxidant food additives like BHA, BHT and TBHQ are facing challenges due to negative consumer perception, prompting food manufacturers to seek safer natural alternatives. Terpenoids and polyphenols, widely distributed in fruits and vegetables, show broad antioxidant effects and have the potential to replace synthetic antioxidants in food preservation, particularly in preventing lipid oxidation in high fat-containing foods.
Article
Chemistry, Applied
Mingfeng Xu, Zhenghao Lian, Xiaoqiao Chen, Xing Yao, Cairu Lu, Xiaoying Niu, Maojun Xu, Qin Zhu
Summary: The study found that resveratrol can significantly inhibit the oxidation of lipids and proteins in emulsions, reducing protein carbonylation and protecting protein sulfhydrl content. At the same time, resveratrol can partially attenuate the decrease in protein solubility caused by oxidation.
Article
Biochemistry & Molecular Biology
Jan Stepniak, Aleksandra Rynkowska, Malgorzata Karbownik-Lewinska
Summary: Iron is essential for many organs but its overload can be toxic. Excessive iron absorption and deposition can lead to diseases like hemochromatosis. This study found that the thyroid is less sensitive to oxidative effects caused by Fenton reaction substrates and melatonin has the same protective effects in different tissues.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Engineering, Chemical
Prasad B. Patil, Sunita Raut-Jadhav, Niraj S. Topare, Aniruddha B. Pandit
Summary: The degradation of acetamiprid, a neonicotinoid pesticide, was enhanced by applying hydrodynamic cavitation (HC) with Fenton and photo-Fenton processes using orifice plate and circular venturi as a cavitating device. Optimization of operating parameters with the circular venturi resulted in the optimum pH of 3 and optimum acetamiprid concentration of 10 ppm. HC-based combined strategies using the circular venturi showed a higher rate of acetamiprid degradation than the orifice plate.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Alex Gibney, Raphael E. F. de Paiva, Vandana Singh, Robert Fox, Damien Thompson, Joseph Hennessy, Creina Slator, Christine J. McKenzie, Pegah Johansson, Vickie McKee, Fredrik Westerlund, Andrew Kellett
Summary: In this study, a Cu-catalysed azide-alkyne cycloaddition reaction produced a 1,2,3-triazole linker that was used to create Cu-binding artificial metallo-nucleases (AMNs). A bioactive C-3-symmetric ligand called TC-Thio was developed using biologically inert reaction partners. The ligand formed Cu-II and Cu-I complexes through Cu coordination, and showed potent DNA binding and cleaving abilities. Mechanistic studies revealed that DNA recognition occurred at the minor groove, leading to oxidative damage through a pathway dependent on superoxide and peroxide. Single molecule imaging demonstrated that the complex caused DNA damage recognized by base excision repair enzymes, comparable to the clinical drug temozolomide.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Food Science & Technology
Adrieni Santos de Oliveira, Bibiana Alves dos Santos, Carla Andressa Almeida Farias, Leticia Pereira Correa, Madison Willy Silva Cordeiro, Mariana Basso Pinton, Milene Teixeira Barcia, Roger Wagner, Alexandre Jose Cichoski, Juliano Smanioto Barin, Jose Manuel Lorenzo, Gema Nieto, Paulo Cezar Bastianello Campagnol
Summary: Hydrogelled emulsions (HEs) of linseed oil and pea protein (PP) were produced with raspberry extract obtained by a green extraction technique. The HEs were used to replace 50% of pork backfat in burgers. The reformulation showed benefits such as reduced fat content, improved PUFA ratio, increased cooking yield, and decreased oxidative defects.
Article
Environmental Sciences
Dylan J. Buglewicz, Cathy Su, Austin B. Banks, Jazmine Stenger-Smith, Suad Elmegerhi, Hirokazu Hirakawa, Akira Fujimori, Takamitsu A. Kato
Summary: Cu2+ and Co2+ metals can increase DNA damage in the presence of hydrogen peroxide. Cu2+ is more efficient than Co2+ at inducing both DNA single-strand and double-strand breaks. The effect of radiation and chemical treatments on Cu2+ and Co2+ varies, with positive correlation for single-strand break formation and negative correlation for double-strand break formation.
Article
Chemistry, Applied
Xin Zhao, Xiaoyu Cheng, Mingwu Zang, Le Wang, Xiang Li, Yijing Yue, Bowen Liu
Summary: The drying process has been found to affect the lipid profile of shrimp and is associated with protein and lipid oxidation.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Article
Chemistry, Applied
Philipp M. Meissner, Julia K. Keppler, Karin Schwarz
Summary: This study investigated lipid oxidation induced protein scission in oleogel using beta-lactoglobulin as gelator. Cleaved peptides were identified using high resolution mass spectrometry and the relevance to lipid hydroperoxide formation was evaluated. The results showed that the most important peptides were located at the protein surface in random coil segments and at the ends of the protein sequence. Cysteine and aliphatic amino acids were the most important amino acids for scission, predominantly through the alpha-amidation pathway. These findings were consistent with previous studies on amino acid depletion caused by lipid oxidation in systems containing bovine albumin or gamma-globulin.
Article
Chemistry, Applied
Antonia Dayane Jenyffer de Farias Marques, Jerffeson de Lima Tavares, Leila Moreira de Carvalho, Thaianaly Leite Abreu, Deyse Alves Pereira, Miriane Moreira Fernandes Santos, Marta Suely Madruga, Lorena Lucena de Medeiros, Taliana Kenia Alencar Bezerra
Summary: The addition of organic coffee husk extract to chicken burgers effectively inhibits lipid oxidation without significant impact on protein oxidation. This additive is considered a potential natural additive that helps reduce agro-industrial by-products generated by the coffee industry.
Article
Chemistry, Applied
Xiangfei Hu, Qiannan Jiang, Hui Wang, Jinlin Li, Zongcai Tu
Summary: This study evaluated the changes in quality attributes, oxidation index, glycosylated hazardous products, and aroma characteristics of grass carp fillets during air-frying, roast-frying, and pan-frying. The levels of carbonyl protein and lipid oxidation products increased significantly with frying (in the order of air-frying > pan-frying > roast-frying), but decreased after 6 minutes. Frying resulted in increased levels of N epsilon-carboxymethyl-lysines (CML) and 5-hydroxymethylfurfural (5-HMF), with pan-frying showing the highest increment. Volatile compounds gradually increased in air-frying, but decreased after 6 minutes in roast-frying and pan-frying.
Article
Food Science & Technology
Oladipupo Odunayo Olatunde, Khursheed Ahmad Shiekh, Soottawat Benjakul
Summary: Cold plasma, as a novel non-thermal technology, shows great potential in seafood preservation. Although there are limitations, these can be overcome by combining CP with antioxidants from natural sources.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Biophysics
Z. Pinar Gumus, Emine Guler, Bilal Demir, F. Baris Barlas, Murat Yavuz, Dilara Colpankan, A. Murat Senisik, Serap Teksoz, Perihan Unak, Hakan Coskunol, Suna Timur
COLLOIDS AND SURFACES B-BIOINTERFACES
(2015)
Article
Materials Science, Biomaterials
Rabia Nur Un, F. Baris Barlas, Murat Yavuz, Didem Ag Seleci, Muharrem Seleci, Z. Pinar Gumus, Emine Guler, Bilal Demir, Mustafa Can, Hakan Coskunol, Suna Timur
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2015)
Article
Polymer Science
Emine Guler, Huseyin Akbulut, Guliz Bozokalfa, Bilal Demir, Gizem Oyman Eyrilmez, Murat Yavuz, Dilek Odaci Demirkol, Hakan Coskunol, Takeshi Endo, Shuhei Yamada, Suna Timur, Yusuf Yagci
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2015)
Article
Chemistry, Multidisciplinary
Didem Ag Seleci, Zinar Pinar Gumus, Murat Yavuz, Muharrem Seleci, Rebecca Bongartz, Frank Stahl, Hakan Coskunol, Suna Timur, Thomas Scheper
TURKISH JOURNAL OF CHEMISTRY
(2015)
Article
Materials Science, Biomaterials
Rabia Nur Un, F. Baris Barlas, Murat Yavuz, Didem Ag Seleci, Muharrem Seleci, Z. Pinar Gumus, Emine Guler, Bilal Demir, Mustafa Can, Hakan Coskunol, Suna Timur
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2015)
Article
Chemistry, Analytical
Mohomodou Maiga, Esra Evrim Yalcinkaya, Burak Sonmez, Debora Puglia, Murat Yavuz, Dilek Odaci Demirkol, Jose M. Kenny, Suna Timur
SENSORS AND ACTUATORS B-CHEMICAL
(2016)
Article
Chemistry, Multidisciplinary
Murat Yavuz, Oguz Cakir, Zubeyde Baysal
TURKISH JOURNAL OF CHEMISTRY
(2016)
Article
Pharmacology & Pharmacy
Aybike Gunes, Emine Guler, Rabia Nur Un, Bilal Demir, E. Baris Barlas, Murat Yavuz, Hakan Coskunol, Suna Timur
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2017)
Article
Biophysics
Emine Guler, F. Baris Barlas, Murat Yavuz, Bilal Demir, Z. Pinar Gumus, Yucel Baspinar, Hakan Coskunol, Suna Timur
COLLOIDS AND SURFACES B-BIOINTERFACES
(2014)
Article
Chemistry, Inorganic & Nuclear
Yesim Salman, Firat Baris Barlas, Murat Yavuz, Kerem Kaya, Suna Timur, Fatma Cetin Telli
INORGANICA CHIMICA ACTA
(2018)
Article
Chemistry, Analytical
Volkan Tekin, F. Zumrut Biber Muftuler, Ozge Kozgus Guldu, Ayfer Yurt Kilcar, E. Ilker Medine, Murat Yavuz, Perihan Unak, Suna Timur
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
(2015)
Article
Polymer Science
Huseyin Akbulut, Murat Yavuz, Emine Guler, Dilek Odaci Demirkol, Takeshi Endo, Shuhei Yamada, Suna Timur, Yusuf Yagci
Article
Food Science & Technology
Zubeyde Baysal, Yasemin Bulut, Murat Yavuz, Cetin Aytekin
Article
Chemistry, Multidisciplinary
B. Demir, F. B. Barlas, E. Guler, P. Z. Gumus, M. Can, M. Yavuz, H. Coskunol, S. Timur
Article
Chemistry, Multidisciplinary
Fatma Cetin Telli, Murat Yavuz, Serpil Denizalti, Yesim Salman
Summary: Carbohydrate-based imidazolium salts conjugated with gold and silver nanoparticles were prepared in this study. The biological evaluation of the synthesized glyconanoconjugates showed radiotherapeutic effects, especially in radiotherapy. The antimicrobial activity of IMSs and their nanoconjugates against test pathogens was also evaluated.
