Article
Chemistry, Multidisciplinary
Yu Mao, Zuoheng Zhang, Hongfeng Zhan, Jianfei Sun, Yan Li, Zhenhuang Su, Yonghua Chen, Xingyu Gao, Xiao Huang, Ning Gu
Summary: The mechanism of coprecipitation formation of iron oxides has been a long-standing challenge. In this study, a specially designed gas/liquid mixed phase fluidic reactor was used to investigate the formation process. The results suggest that the initial Fe3+ ions hydrolyze to form Fe(OH)(3), which then dehydrates to yield alpha-FeOOH. In the presence of Fe2+ ions, alpha-FeOOH finally transforms to Fe3O4.
CHEMICAL COMMUNICATIONS
(2022)
Article
Physics, Multidisciplinary
Yanshuang Chen, Zhenwei Yao, Shixiang Tang, Hua Tong, Taiki Yanagishima, Hajime Tanaka, Peng Tan
Summary: The study investigates the effect of spherical confinement and curvature-induced topological defects on the crystallization of charged colloids, concluding that crystallization in spherical confinement is due to a combination of thermodynamics and kinetic pathways.
Article
Chemistry, Physical
Bihan Zhang, Zhennan Wu, Yitao Cao, Qiaofeng Yao, Jianping Xie
Summary: Increasing surface charge effectively improves stability of hydrophilic gold nanoclusters in solution, with sulfonic thiolate ligands showing promising results. This strategy can enhance stability under various conditions, making it suitable for biomedical and catalytic applications.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Multidisciplinary
Jette K. Mathiesen, Jonathan Quinson, Sonja Blaseio, Emil T. S. Kjaer, Alexandra Dworzak, Susan R. Cooper, Jack K. Pedersen, Baiyu Wang, Francesco Bizzotto, Johanna Schroeder, Tiffany L. Kinnibrugh, Soren B. Simonsen, Luise Theil Kuhn, Jacob J. K. Kirkensgaard, Jan Rossmeisl, Mehtap Oezaslan, Matthias Arenz, Kirsten M. o. Jensen
Summary: In this study, a surfactant-free synthesis method was used to prepare colloidal iridium nanoparticles. The formation routes and structures of the nanoparticles were investigated using in situ X-ray total scattering experiments. It was found that the precursor salt used greatly influenced the formation process and resulting structure of the nanoparticles. This study provides valuable insights into the formation and growth of iridium nanoparticles.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Inorganic & Nuclear
Jing Sun, Xiongkai Tang, Jiaqi Tang, Yuhao Zhang, Zilin Li, Hui Chaolumen, Shuo Guo, Hui Shen
Summary: Little progress has been made in developing alternative bottom-up synthetic strategies for N-heterocyclic carbene (NHC)-stabilized gold nanoclusters, but this study presents a simple and straightforward approach using imidazolium salts instead of free carbenes or NHC-coordinated gold complexes as precursors. The researchers successfully synthesized an NHC-stabilized Au13Br4 cluster using a one-pot and one-step process involving chemical reduction. This work not only expands the Au13 library with a new NHC-ligated superatom, but also provides a facile and reasonable method to explore similar analogues.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Vikas Tiwari, Tarak Karmakar
Summary: Monolayer-protected atomically precise nanoclusters (MPCs) are important molecules with unique structural features and diverse applications. In this study, we used molecular dynamics and enhanced sampling simulations to understand the atomistic and dynamical details of the aggregation process of Au-25(pMBA)(18) MPCs in aqueous and methanol solutions. The results showed that MPCs interact via hydrogen bonds and π-stacks between aromatic ligands to form stable dimers, oligomers, and crystals. The study also revealed the role of ligand charged state and solvent in molecular aggregation. Our work provides unprecedented molecular-level dynamical details of the aggregation process and conformational dynamics of MPCs ligands in solution and crystalline phases.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Review
Chemistry, Multidisciplinary
Leyi Chen, Lei Wang, Quanli Shen, Yonggang Liu, Zhenghua Tang
Summary: Atomically precise metal nanoclusters have attracted significant research interest due to their quantum confinement effect and molecule-like properties. Ligand engineering, especially using alkynyl molecules, can lead to versatile interfacial bonding motifs and drastically different properties compared to thiolate ligands. This review discusses the unique advantages of alkynyl-protected metal nanoclusters, synthetic strategies, their applications in electrochemical CO2 reduction, and proposes challenges and future perspectives. The review aims to stimulate further research efforts in developing effective synthesis strategies and advancing the understanding of alkynyl-protected metal nanoclusters in catalysis.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Papri Chakraborty, Sami Malola, Marco Neumaier, Patrick Weis, Hannu Hakkinen, Manfred M. Kappes
Summary: The fragmentation dynamics of ligated coinage metal clusters provides insights into their structural and bonding properties. However, the challenges in methodology have limited the investigation of fragment structures. In this study, we used trapped ion mobility mass spectrometry to determine the geometric structures of the primary fragments of [Ag29L12](3-) and compared them to density functional theory calculations. We also observed a new dissociation channel in the further dissociation of [Ag19L6](-), indicating a competition between retaining electronic stability and increasing steric strain of ligands and staples. These findings have potential implications for studying the catalytic behavior of Ag clusters on supports through soft-landing deposition.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Tsubasa Omoda, Shinjiro Takano, Shinya Masuda, Tatsuya Tsukuda
Summary: By introducing up to 12 second generation poly(benzyl ether)dendron-thiols (D2SH) into the Au-13 core of [Au-23(ScC6H11)(16)](-), the optical absorbance and quantum yield of photoluminescence were significantly enhanced in specific energy regions.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Inorganic & Nuclear
Peipei Sun, Xiongkai Tang, Weijie Yang, Xiang Wang, Rui Zhou, Ning Chen, Shang-Fu Yuan
Summary: In this study, two novel N-heterocyclic thione-protected silver clusters were reported, which could form cluster-based molecular crystals with high thermal stability. This work lays a foundation for the synthesis of atomically precise and stable silver clusters using readily available N-heterocyclic thione ligands.
INORGANIC CHEMISTRY
(2022)
Article
Spectroscopy
Cheng Cheng, Juan Qiao, Hongyi Zhang, Zhenwen Zhao, Li Qi
Summary: Recently, the loading of polymer-ligand onto the surface of gold nanoparticles as nanozymes has attracted attention. A study reported a method to modulate the peroxidase-mimic catalytic capability of PNIPAM@AuNPs by changing temperature. The presence of glutathione inhibits the generation of oxidized TMB, and the method could be used for the analysis of serum glutathione.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Food Science & Technology
Shengnan Wei, Zhenyue Su, Xiangong Bu, Xuening Shi, Bo Pang, Liang Zhang, Juan Li, Chao Zhao
Summary: A colorimetric assay aptasensor for the detection of Salmonella typhimurium was developed using gold nanoparticles embedded spherical covalent organic framework with peroxidase-like activity and the affinity and specificity of S. typhimurium-aptamer. The aptasensor showed a low detection limit and good recovery rates, and can be combined with a smartphone-based image analysis system for point-of-care testing.
NPJ SCIENCE OF FOOD
(2022)
Article
Chemistry, Analytical
Wei-Feng Wang, Stanislas Nsanzamahoro, Ying Zhang, Cheng-Bo Wang, Yan-Ping Shi, Jun-Li Yang
Summary: In this study, a facile and sensitive sensing platform based on CQD-silver nanocomposites was developed for colorimetric detection of alkaline phosphatase. The method allows for visual and fast evaluation of ALP activity and can be used to screen ALP inhibitors.
ANALYTICAL METHODS
(2022)
Article
Multidisciplinary Sciences
Alexander E. S. Van Driessche, Nani Van Gerven, Rick R. M. Joosten, Wai Li Ling, Maria Bacia, Nico Sommerdijk, Mike Sleutel
Summary: The study utilized cryo-transmission electron microscopy to map the self-assembly route of protein crystals at high nucleation rates, revealing the importance of interactions between crystalline nuclei and the impact of oriented attachment on the protein crystallization process.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Hong Yi, Kimberly M. Osten, Tetyana Levchenko, Alex J. Veinot, Yoshitaka Aramaki, Takashi Ooi, Masakazu Nambo, Cathleen M. Crudden
Summary: A series of chiral Au-13 nanoclusters were successfully synthesized and characterized, exhibiting high luminescence and stability. This opens up opportunities for further investigation into the impact of chirality on the properties of these clusters.
Article
Biochemistry & Molecular Biology
Kyle W. Anderson, Natalia Mast, Jeffrey W. Hudgens, Joseph B. Lin, Illarion V. Turko, Irina A. Pikuleva
JOURNAL OF BIOLOGICAL CHEMISTRY
(2016)
Article
Chemistry, Analytical
Kyle W. Anderson, Elyssia S. Gallagher, Jeffrey W. Hudgens
ANALYTICAL CHEMISTRY
(2018)
Article
Multidisciplinary Sciences
Sergiy Tyukhtenko, Girija Rajarshi, Ioannis Karageorgos, Nikolai Zvonok, Elyssia S. Gallagher, Hongwei Huang, Kiran Vemuri, Jeffrey W. Hudgens, Xiaoyu Ma, Mahmoud L. Nasr, Spiro Pavlopoulos, Alexandros Makriyannis
SCIENTIFIC REPORTS
(2018)
Article
Biochemistry & Molecular Biology
Richard Y-C Huang, Jeffrey W. Hudgens
Article
Biochemistry & Molecular Biology
Zhuo Li, Richard Y. -C. Huang, Daniel C. Yopp, Travis H. Hileman, Thomas J. Santangelo, Jerard Hurwitz, Jeffrey W. Hudgens, Zvi Kelman
NUCLEIC ACIDS RESEARCH
(2014)
Article
Multidisciplinary Sciences
Steven M. Swift, Jeffrey W. Hudgens, Ryan D. Heselpoth, Patrick M. Bales, Daniel C. Nelson
Article
Chemistry, Analytical
Jeffrey W. Hudgens, Elyssia S. Gallagher, Ioannis Karageorgos, Kyle W. Anderson, James J. Filliben, Richard Y. -C. Huang, Guodong Chen, George M. Bou-Assaf, Alfonso Espada, Michael J. Chalmers, Eduardo Harguindey, Hui-Min Zhang, Benjamin T. Walters, Jennifer Zhang, John Venable, Caitlin Steckler, Inhee Park, Ansgar Brock, Xiaojun Lu, Ratnesh Pandey, Arun Chandramohan, Ganesh Srinivasan Anand, Sasidhar N. Nirudodhi, Justin B. Sperry, Jason C. Rouse, James A. Carroll, Kasper D. Rand, Ulrike Leurs, David D. Weis, Mohammed A. Al-Naqshabandi, Tyler S. Hageman, Daniel Deredge, Patrick L. Wintrode, Malvina Papanastasiou, John D. Lambris, Sheng Li, Sarah Urata
ANALYTICAL CHEMISTRY
(2019)
Article
Instruments & Instrumentation
Jeffrey W. Hudgens, Elyssia S. Gallagher, Ioannis Karageorgos, Kyle W. Anderson, Richard Y-C Huang, Guodong Chen, George M. Bou-Assaf, Alfonso Espada, Michael J. Chalmers, Eduardo Harguindey, Hui-Min Zhang, Benjamin T. Walters, Jennifer Zhang, John Venable, Caitlin Steckler, Inhee Park, Ansgar Brock, Xiaojun Lu, Ratnesh Pandey, Arun Chandramohan, Ganesh Srinivasan Anand, Sasidhar N. Nirudodhi, Justin B. Sperry, Jason C. Rouse, James A. Carroll, Kasper D. Rand, Ulrike Leurs, David D. Weis, Mohammed A. Al-Naqshabandi, Tyler S. Hageman, Daniel Deredge, Patrick L. Wintrode, Malvina Papanastasiou, John D. Lambris, Sheng Li, Sarah Urata
JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY
(2019)
Article
Instruments & Instrumentation
Jeffrey W. Hudgens
JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY
(2020)
Article
Instruments & Instrumentation
Kyle W. Anderson, Kerry Scott, Ioannis L. Karageorgos, Elyssia S. Gallagher, Venkata S. Tayi, Michael Butler, Jeffrey W. Hudgens
JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Kyle W. Anderson, Christina Bergonzo, Kerry Scott, Ioannis L. Karageorgos, Elyssia S. Gallagher, Venkata S. Tayi, Michael Butler, Jeffrey W. Hudgens
Summary: Previous studies have proposed different models for stabilizing the Fc-Fc gamma RI immune complex. This study used multiple experimental methods to investigate the role of glycoprotein interactions between IgG1 glycans and the FG-loop of Fc gamma RIa in complex stabilization. The results showed that both intermolecular and intramolecular glycoprotein bonds contribute to the stability of the complex.
JOURNAL OF MOLECULAR BIOLOGY
(2022)
Article
Biochemical Research Methods
Kyle W. Anderson, Jeffrey W. Hudgens
Summary: To improve the reproducibility of HDX-MS in the quality control of biopharmaceuticals, researchers have developed a dual-enzyme HDX-MS instrument that conducts liquid chromatography separations at subzero temperature. This instrument reduces back-exchange and supports longer separations with improved resolution.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2022)
Article
Biochemical Research Methods
Kyle W. Anderson, Jeffrey W. Hudgens
Summary: Chromatographic separations at subzero temperature improve the precision of back-exchange-corrected HDX-MS determinations. A dual-enzyme HDX-MS analysis instrument with a RPLC trap column and a HILIC analytical column in a two-dimensional RPLC-HILIC configuration at subzero temperature was designed and performed. The HILIC column at -30°C showed reduced backpressure, enabling faster flow rates and the use of materials rated for lower maximum pressures.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
(2023)
Article
Multidisciplinary Sciences
Sergiy Tyukhtenko, Xiaoyu Ma, Girija Rajarshi, Ioannis Karageorgos, Kyle W. Anderson, Jeffrey W. Hudgens, Jason J. Guo, Mahmoud L. Nasr, Nikolai Zvonok, Kiran Vemuri, Gerhard Wagner, Alexandros Makriyannis
SCIENTIFIC REPORTS
(2020)
Article
Biochemistry & Molecular Biology
Sharlyn J. Mazur, Elyssia S. Gallagher, Subrata Debnath, Stewart R. Durell, Kyle W. Anderson, Lisa M. Miller Jenkins, Ettore Appella, Jeffrey W. Hudgens