Conserved and divergent aspects of human T-cell development and migration in humanized mice

Tracking migration during human T cell development

(2014) Joanna Halkias et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Thymocyte-Dendritic Cell Interactions near Sources of CCR7 Ligands in the Thymic Cortex

(2014) E. Ladi et al.   JOURNAL OF IMMUNOLOGY

Fetal Regulatory T Cells and Peripheral Immune ToleranceIn Utero: Implications for Development and Disease

(2013) Trevor D. Burt   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Opposing chemokine gradients control human thymocyte migration in situ

(2013) Joanna Halkias et al.   JOURNAL OF CLINICAL INVESTIGATION

The thymic medulla is required for Foxp3+regulatory but not conventional CD4+thymocyte development

(2013) Jennifer E. Cowan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+regulatory T cell development via the CD27–CD70 pathway

(2013) Jonathan M. Coquet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Distinct Temporal Patterns of T Cell Receptor Signaling During Positive Versus Negative Selection in Situ

(2013) H. J. Melichar et al.   Science Signaling

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis

(2012) Joan Yuan et al.   SCIENCE

Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2R null humanized mice

(2011) E. Billerbeck et al.   BLOOD

Autonomous and extrinsic regulation of thymopoiesis inhuman immune system (HIS) mice

(2011) Nicholas D. Huntington et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

(2011) Yu Lei et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Requirements for Eomesodermin and Promyelocytic Leukemia Zinc Finger in the Development of Innate-Like CD8+ T Cells

(2011) S. M. Gordon et al.   JOURNAL OF IMMUNOLOGY

MHC Class II-Restricted Interaction between Thymocytes Plays an Essential Role in the Production of Innate CD8+ T Cells

(2011) H. S. Min et al.   JOURNAL OF IMMUNOLOGY

IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo

(2011) N. D. Huntington et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parameters for establishing humanized mouse models to study human immunity: Analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rγnull mutation

(2010) Michael A. Brehm et al.   CLINICAL IMMUNOLOGY

Human cytomegalovirus elicits fetal γδ T cell responses in utero

(2010) David Vermijlen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells

(2010) Michael A Weinreich et al.   NATURE IMMUNOLOGY

Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes

(2010) Georges A. Azar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r null humanized mice

(2010) L. D. Shultz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/γc−/−, Balb/c-Rag1−/−γc−/−, and C.B-17-scid/bg immunodeficient mice

(2009) Christin M. Lepus et al.   HUMAN IMMUNOLOGY

Generation of PLZF+CD4+T cells via MHC class II–dependent thymocyte–thymocyte interaction is a physiological process in humans

(2009) You Jeong Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

(2009) Till Strowig et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The impact of negative selection on thymocyte migration in the medulla

(2009) Marie Le Borgne et al.   NATURE IMMUNOLOGY

Dengue Virus Infection and Virus-Specific HLA-A2 Restricted Immune Responses in Humanized NOD-scid IL2rγnull Mice

(2009) Smita Jaiswal et al.   PLoS One

Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

(2009) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cells in the thymus contribute to T-regulatory cell induction

(2008) A. I. Proietto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human intrathymic development: a selective approach

(2008) J. Plum et al.   Seminars in Immunopathology