Activation of the endoplasmic reticulum stress sensor IRE1α by the vaccine adjuvant AS03 contributes to its immunostimulatory properties
出版年份 2018 全文链接
标题
Activation of the endoplasmic reticulum stress sensor IRE1α by the vaccine adjuvant AS03 contributes to its immunostimulatory properties
作者
关键词
-
出版物
npj Vaccines
Volume 3, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-05-21
DOI
10.1038/s41541-018-0058-4
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cell-Based Systems Biology Analysis of Human AS03-Adjuvanted H5N1 Avian Influenza Vaccine Responses: A Phase I Randomized Controlled Trial
- (2017) Leigh M. Howard et al. PLoS One
- Impact of adjuvants on CD4 + T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial
- (2016) Geert Leroux-Roels et al. CLINICAL IMMUNOLOGY
- IL-18 and Subcapsular Lymph Node Macrophages are Essential for Enhanced B Cell Responses with TLR4 Agonist Adjuvants
- (2016) Anthony L. Desbien et al. JOURNAL OF IMMUNOLOGY
- Antigen-presenting cell-derived IL-6 restricts the expression of GATA3 and IL-4 by follicular helper T cells
- (2016) Mélanie Hercor et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The role of ER stress in lipid metabolism and lipotoxicity
- (2016) Jaeseok Han et al. JOURNAL OF LIPID RESEARCH
- Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events
- (2016) Olga Sobolev et al. NATURE IMMUNOLOGY
- Central Role of CD169+ Lymph Node Resident Macrophages in the Adjuvanticity of the QS-21 Component of AS01
- (2016) Sophie Detienne et al. Scientific Reports
- Phenylbutyric Acid: Simple Structure - Multiple Effects
- (2015) Magdalena Kusaczuk et al. CURRENT PHARMACEUTICAL DESIGN
- Non-clinical safety and biodistribution of AS03-adjuvanted inactivated pandemic influenza vaccines
- (2015) Lawrence Segal et al. JOURNAL OF APPLIED TOXICOLOGY
- Vaccine Adjuvant MF59 Promotes Retention of Unprocessed Antigen in Lymph Node Macrophage Compartments and Follicular Dendritic Cells
- (2015) Rocco Cantisani et al. JOURNAL OF IMMUNOLOGY
- Emerging functions of the unfolded protein response in immunity
- (2014) Sophie Janssens et al. NATURE IMMUNOLOGY
- Th1/Th2 Paradigm Extended: Macrophage Polarization as an Unappreciated Pathogen-Driven Escape Mechanism?
- (2014) Eric Muraille et al. Frontiers in Immunology
- Role of vitamin E as a lipid-soluble peroxyl radical scavenger: in vitro and in vivo evidence
- (2013) Etsuo Niki FREE RADICAL BIOLOGY AND MEDICINE
- The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination
- (2013) M. Vono et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect
- (2013) Samuele Calabro et al. VACCINE
- Development and evaluation of AS03, an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion
- (2012) Nathalie Garçon et al. Expert Review of Vaccines
- InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation
- (2012) Karin Breuer et al. NUCLEIC ACIDS RESEARCH
- Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells
- (2012) G. Clavarino et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Follicular Helper CD4 T Cells (TFH)
- (2011) Shane Crotty Annual Review of Immunology
- Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways
- (2011) Thanyarat Promlek et al. MOLECULAR BIOLOGY OF THE CELL
- Systems biology of vaccination for seasonal influenza in humans
- (2011) Helder I Nakaya et al. NATURE IMMUNOLOGY
- DNA released from dying host cells mediates aluminum adjuvant activity
- (2011) Thomas Marichal et al. NATURE MEDICINE
- IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation
- (2011) Danelle Eto et al. PLoS One
- Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88
- (2011) A. Seubert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59
- (2011) A. H. Ellebedy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Membrane lipidome of an epithelial cell line
- (2011) Julio L. Sampaio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Late Interleukin-6 Escalates T Follicular Helper Cell Responses and Controls a Chronic Viral Infection
- (2011) J. A. Harker et al. SCIENCE
- Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes
- (2011) Samuele Calabro et al. VACCINE
- Adjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity
- (2011) Sandra Morel et al. VACCINE
- A novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language
- (2011) Ronny Herzog et al. GENOME BIOLOGY
- Vaccine Adjuvants: Putting Innate Immunity to Work
- (2010) Robert L. Coffman et al. IMMUNITY
- TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
- (2010) Fabio Martinon et al. NATURE IMMUNOLOGY
- Squalene-based oil-in-water emulsion adjuvants perturb metabolism of neutral lipids and enhance lipid droplet formation
- (2009) Lucie Kalvodova BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+T cells
- (2009) Oliver Dienz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis
- (2009) Ebru Erbay et al. NATURE MEDICINE
- Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
- (2009) T. Iwawaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipid-Induced ER Stress: Synergistic Effects of Sterols and Saturated Fatty Acids
- (2009) Ludovic Pineau et al. TRAFFIC
- Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages
- (2008) Roza I. Nurieva et al. IMMUNITY
- Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
- (2008) Mirjam Kool et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Novel Transcriptional Activities of Vitamin E: Inhibition of Cholesterol Biosynthesis†
- (2007) Scott Valastyan et al. BIOCHEMISTRY
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